最終更新: 2026-01-19

上部消化管グループ

2026年(2件)

• Hatta W, Ogata Y, Ogasawara K, Hatayama Y, Saito M, Kanno T, Koike T, Masamune ARecent Advances in Endoscopic Submucosal Dissection for Gastric Cancer: Focusing on Expanded Indications and Technological Innovations.J Gastric Cancer ( 2026) 26(1): 76-91PMID : 41517849
• Kanno T, Hatayama Y, Suzuki S, Hatta W, Uno K, Koike T, Masamune AHigh-fidelity endoscopic submucosal dissection simulator reproducing full-procedure training, bleeding, and perforation.Endoscopy ( 2026) 58(S 01): E23-E25PMID : 41506285

2025年(12件)

• Tanno N, Hatta W, Ogata Y, Kayada K, Kawabe M, Hatayama Y, Saito M, Imatani A, Koike T, Nakamura T, Nakaya N, Masamune APrognostic Effect of Impaired Skeletal Muscle Assessed with Computed Tomography Images in Patients with Endoscopic Resection for Esophageal Squamous Cell Carcinoma.Digestion ( 2025) 1-12PMID : 40971345
• Asano N, Koike T, Saito M, Hatayama Y, Ogata Y, Jin X, Kanno T, Hatta W, Uno K, Imatani A, Masamune AEtiology and pathophysiology of Barrett's esophagus/neoplasia.Digestion ( 2025) 1-14PMID : 40952946
• Kusano K, Uno K, Tamahara T, Asano N, Sudo K, Tanabe M, Ogasawara K, Kanno T, Koike T, Shimizu R, Masamune AMetabolic syndrome develops cardia cancer via nuclear factor-E2-related factor 2-programmed death-ligand 1 signaling.Cell Mol Gastroenterol Hepatol ( 2025) 101629PMID : 40935246
• Abe H, Hatta W, Tarasawa K, Hatayama Y, Ogata Y, Saito M, Jin X, Koike T, Imatani A, Hamada S, Fujimori K, Fushimi K, Masamune AEffect of oral proton pump inhibitor administration on reducing the delayed bleeding risk in five upper gastrointestinal endoscopic treatments.Am J Gastroenterol ( 2025) PMID : 40844513
• Kajiura H, Uno K, Kume K, Koike T, Saito M, Shimoyama Y, Ninomiya M, Oguro S, Takase K, Masamune AUsefulness of double-balloon endoscopy-assisted injection sclerotherapy for hemorrhagic varices in the jejunum reconstructed for liver transplantation in a pediatric case.Clin J Gastroenterol ( 2025) 18(4): 619-625PMID : 40423842
• Shuto Y, Saito M, Koike T, Koizumi K, Kaise Y, Yachi K, Hatayama Y, Ogata Y, Jin X, Kanno T, Hatta W, Uno K, Asano N, Imatani A, Masamune AAssociations between excessive supragastric belching and esophageal reflux factors in patients with PPI-refractory GERD in Japan.J Gastroenterol ( 2025) 60(9): 1070-1078PMID : 40353903
• Sudo K, Uno K, Tamahara T, Asano N, Kusano K, Tanabe M, Ogasawara K, Kanno T, Koike T, Shimizu R, Masamune ACo-stimulation with high-fat diet and acidic bile salts may promote Warburg effect in gastric carcinogenesis around the squamo-columnar junction in Gan mice.Am J Physiol Gastrointest Liver Physiol ( 2025) PMID : 40246521
• Ogata Y, Hatta W, Kanno T, Hatayama Y, Saito M, Jin X, Koike T, Imatani A, Yuan Y, Masamune APrevalence and risk factors for lymph node metastasis in duodenal neuroendocrine tumors: a systematic review and meta-analysis.J Gastroenterol ( 2025) 60(6): 673-682PMID : 40178634
• Ogata Y, Hatta W, Kanno T, Saito M, Jin X, Asano N, Koike T, Imatani A, Yuan Y, Masamune AType 2 and type 3 gastric neuroendocrine tumors have high risk of lymph node metastasis: Systematic review and meta-analysis.Dig Endosc ( 2025) 37(8): 834-843PMID : 40170116
• Hatta W, Abe H, Tarasawa K, Hatta W, Tanno N, Hatayama Y, Ogata Y, Saito M, Jin X, Koike T, Imatani A, Hamada S, Fujimori K, Fushimi K, Masamune AWhich of Vonoprazan Alone or Intravenous Proton Pump Inhibitor Followed by Vonoprazan Is Optimal for Reducing Delayed Bleeding in Gastric Endoscopic Submucosal Dissection?Digestion ( 2025) 106(5): 406-415PMID : 40132569
• Mizumoto N, Abe Y, Sasaki Y, Yagi M, Onozato Y, Takahashi Y, Ara N, Nomura E, Kawamura M, Takahashi S, Asonuma S, Shoji M, Kondo Y, Iwai W, Kikuchi R, Saito M, Hatta W, Koike T, Matsuhashi T, Iijima K, Masamune A, Ueno YPrevalence and Distribution of Gastric Endoscopy Findings in Non-eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Influence of Atrophic Gastritis.Intern Med ( 2025) 64(8): 1161-1170PMID : 39261065
• Yachi K, Hatta W, Koike T, Kayada K, Tanno N, Ogata Y, Saito M, Jin X, Uno K, Asano N, Imatani A, Watanabe H, Fujishima F, Masamune AGastric Leiomyosarcoma Completely Resected by Endoscopic Submucosal Dissection after a Precise Preoperative Diagnosis.Intern Med ( 2025) 64(5): 705-709PMID : 39085073

2024年(14件)

• Sawada A, Hoshikawa Y, Hosaka H, Saito M, Tsuru H, Kato S, Ihara E, Koike T, Uraoka T, Kasugai K, Iwakiri K, Sifrim D, Pandolfino JE, Taft TH, Fujiwara YValidation of the Japanese version of the Esophageal Hypervigilance and Anxiety Scale for esophageal symptoms.J Gastroenterol ( 2024) PMID : 39652101
• Ono Y, Hatta W, Tarasawa K, Ogata Y, Abe H, Sato I, Hatayama Y, Saito M, Jin X, Uno K, Koike T, Imatani A, Hamada S, Fujimori K, Fushimi K, Masamune AOptimal direct oral anticoagulant for upper gastrointestinal endoscopic submucosal dissection.J Gastroenterol ( 2024) PMID : 39601804
• Kaise Y, Uno K, Ogata Y, Saito M, Jin X, Hatta W, Koike T, Ota H, Takase K, Masamune AA case of esophagogastric submucosal hematoma with hemorrhagic shock.Clin J Gastroenterol ( 2024) PMID : 39570503
• Tanabe M, Saito M, Uno K, Koike T, Sato C, Hatta W, Asano N, Fujishima F, Kamei T, Masamune AA Case of Superficial Esophageal Neuroendocrine Carcinoma with Marked Morphological Changes in a Short Period.Intern Med ( 2024) PMID : 39496452
• Ishizawa K, Tamahara T, Suzuki S, Hatayama Y, Li B, Abe M, Aoki Y, Arita R, Saito N, Ohsawa M, Kaneko S, Ono R, Takayama S, Shimada M, Kumada K, Koike T, Masamune A, Onodera K, Ishii T, Shimizu R, Kanno TSequential Sampling of the Gastrointestinal Tract to Characterize the Entire Digestive Microbiome in Japanese Subjects.Microorganisms ( 2024) 12(7):PMID : 39065094
• Hatta W, Koike T, Asano N, Hatayama Y, Ogata Y, Saito M, Jin X, Uno K, Imatani A, Masamune AThe Impact of Tobacco Smoking and Alcohol Consumption on the Development of Gastric Cancers.Int J Mol Sci ( 2024) 25(14):PMID : 39063094
• Suzuki S, Saito M, Uno K, Asano N, Koike T, Akamatsu D, Mizuma M, Kamei T, Unno M, Masamune AThe usefulness of gel immersion endoscopy in identifying herald bleeding from an infectious aortoenteric fistula: a case report.Clin J Gastroenterol ( 2024) 17(5): 871-875PMID : 39039400
• Tanaka I, Hatta W, Koike T, Takahashi S, Shimada T, Hikichi T, Toya Y, Onozato Y, Hamada K, Fukushi D, Watanabe K, Kayaba S, Ito H, Tatsuta T, Oikawa T, Takahashi Y, Kondo Y, Yoshimura T, Shiroki T, Nagino K, Hanabata N, Funakubo A, Ohira T, Nakamura J, Nakamura T, Nakaya N, Iijima K, Matsumoto T, Fukuda S, Masamune A, Hirasawa DRisk factors and pattern of metastatic recurrence after endoscopic resection with additional treatment for esophageal cancer.Dis Esophagus ( 2024) PMID : 38869095
• Ogata Y, Hatta W, Masamune AEndoscopic muscularis dissection with over-the-scope clip: Novel resection technique for duodenal neuroendocrine tumors.Dig Endosc ( 2024) PMID : 38804154
• Hayashi Y, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Kurakami H, Fujishiro M, Masamune A, Takehara TEndoscopic features of synchronous multiple early gastric cancers: Findings from a nationwide cohort.Digestion ( 2024) PMID : 38697038
• Asonuma S, Hatta W, Koike T, Okata H, Uno K, Iwai W, Saito M, Yonechi M, Fukushi D, Kayaba S, Kikuchi R, Ito H, Fushiya J, Maejima R, Abe Y, Kawamura M, Honda J, Kondo Y, Dairaku N, Toda S, Watanabe K, Takahashi K, Echigo H, Abe Y, Endo H, Okata T, Hoshi T, Kinoshita K, Kisoi M, Nakamura T, Nakaya N, Iijima K, Masamune ARisk stratification of synchronous gastric cancers including alcohol-related genetic polymorphisms.J Gastroenterol Hepatol ( 2024) PMID : 38628101
• Ogata Y, Hatta W, Koike T, Takahashi S, Matsuhashi T, Iwai W, Asonuma S, Okata H, Ohyauchi M, Ito H, Abe Y, Sasaki Y, Kawamura M, Saito M, Uno K, Fujishima F, Nakamura T, Nakaya N, Iijima K, Masamune AIs blue light imaging without magnification satisfactory as screening for esophageal squamous cell carcinoma? Post-hoc analysis of multicenter randomized controlled trial.Dig Endosc ( 2024) PMID : 38494659
• Hatayama Y, Kanno T, Takikawa T, Matsumoto R, Arata Y, Suzuki S, Ogata Y, Saito M, Jin X, Miura S, Hatta W, Hamada S, Uno K, Kume K, Kikuta K, Asano N, Imatani A, Koike T, Masamune AA novel dry simulator model for learning comprehensive endoscopic retrograde cholangiopancreatography/endoscopic sphincterotomy procedures while minimizing adverse bleeding events (with Video).Digestion ( 2024) PMID : 38198778
• Hatta W, Gotoda T, Ogata Y, Koike T, Masamune AW-eCura score versus eCura system: comparison in the external cohort is required.Gut ( 2024) 73(11): e24PMID : 38160044

2023年(14件)

• Oriuchi M, Lee S, Uno K, Sudo K, Kusano K, Asano N, Hamada S, Hatta W, Koike T, Imatani A, Masamune APorphyromonas gingivalis Lipopolysaccharide Damages Mucosal Barrier to Promote Gastritis-Associated Carcinogenesis.Dig Dis Sci ( 2023) PMID : 37943385
• Abe H, Tarasawa K, Hatta W, Koike T, Sato I, Ono Y, Ogata Y, Saito M, Jin X, Kanno T, Uno K, Asano N, Imatani A, Fujimori K, Fushimi K, Masamune ASimilar Effect of Vonoprazan and Oral Proton Pump Inhibitors for Preventing Rebleeding in Cases of Upper Gastrointestinal Bleeding.Intern Med ( 2023) PMID : 37558479
• Asano N, Imatani A, Takeuchi A, Saito M, Jin XY, Hatta W, Uno K, Koike T, Masamune ARole of T-box transcription factor 3 in gastric cancers.World J Gastrointest Pathophysiol ( 2023) 14(2): 12-20PMID : 37035275
• Abe H, Saito M, Uno K, Koike T, Ichikawa S, Saito M, Kanno T, Hatta W, Asano N, Masamune AA case of refractory bleeding from duodenal angioectasia with acquired hemophilia A.Clin J Gastroenterol ( 2023) PMID : 37022595
• Kanno T, Arata Y, Hatayama Y, Koike T, Masamune ANovel simulator of endoscopic hemostasis with actual endoscope and devices.VideoGIE ( 2023) 8(2): 56-59PMID : 36820256
• Ogata Y, Hatta W, Koike T, Takahashi S, Matsuhashi T, Oikawa T, Iwai W, Asonuma S, Okata H, Ohyauchi M, Ito H, Abe Y, Sasaki Y, Kawamura M, Saito M, Uno K, Fujishima F, Nakamura T, Nakaya N, Iijima K, Masamune ABlue light imaging and linked color imaging as a screening mode for esophageal squamous cell carcinoma in high-risk patients: A multicenter randomized trial.Dig Endosc ( 2023) PMID : 36802097
• Hatta W, Koike T, Asonuma S, Okata H, Uno K, Oikawa T, Iwai W, Yonechi M, Fukushi D, Kayaba S, Kikuchi R, Ohyauchi M, Fushiya J, Maejima R, Abe Y, Kawamura M, Honda J, Kondo Y, Dairaku N, Norita K, Watanabe K, Takahashi K, Echigo H, Abe Y, Endo H, Okata T, Hoshi T, Nakamura T, Nakaya N, Iijima K, Masamune ASmoking history and severe atrophic gastritis assessed by pepsinogen are risk factors for the prevalence of synchronous gastric cancers in patients with gastric endoscopic submucosal dissection: a multicenter prospective cohort study.J Gastroenterol ( 2023) 58(5): 433-443PMID : 36786863
• Hatta W, Gotoda T, Koike T, Masamune AWhich of endoscopic submucosal dissection or surgery should be selected in patients who have early gastric cancer with a risk factor for noncurative resection?Dig Endosc ( 2023) PMID : 36756747
• Sugawara H, Kanno T, Saito M, Jin X, Hatta W, Uno K, Asano N, Imatani A, Fujishima F, Koike T, Masamune ADiscrepancy between Abdominal Symptoms and Endoscopic Findings in Patients with Gastro-duodenal Eosinophilia: A Case Series.Intern Med ( 2023) PMID : 36754406
• Miura Y, Tsuji Y, Yoshio T, Hatta W, Yabuuchi Y, Hoteya S, Kikuchi D, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Masamune A, Fujishiro MAssociation between perioperative management of antiplatelet agents and risk of post-endoscopic submucosal dissection bleeding in early gastric cancer: an analysis of a nationwide multicenter study.Gastrointest Endosc ( 2023) PMID : 36639059
• Hatta W, Toya Y, Shimada T, Hamada K, Watanabe K, Nakamura J, Fukushi D, Koike T, Shinkai H, Ito H, Matsuhashi T, Fujimori S, Iwai W, Hanabata N, Shiroki T, Sasaki Y, Fujishima Y, Tsuji T, Yorozu H, Yoshimura T, Horikawa Y, Takahashi Y, Takahashi H, Kondo Y, Fujiwara T, Mizugai H, Gonai T, Tatsuta T, Onochi K, Kudara N, Abe K, Ogata Y, Ohira T, Horikawa Y, Ishihata R, Hikichi T, Satoh K, Iijima K, Fukuda S, Matsumoto T, Masamune ATreatment strategy after noncurative endoscopic resection for early gastric cancers in patients aged ≥ 85 years: a multicenter retrospective study in a highly aged area of Japan.J Gastroenterol ( 2023) 58(4): 346-357PMID : 36633664
• Takahashi S, Hatta W, Watanabe K, Koike T, Shimada T, Hikichi T, Toya Y, Tanaka I, Onozato Y, Hamada K, Fukushi D, Watanabe K, Kayaba S, Ito H, Mikami T, Oikawa T, Takahashi Y, Kondo Y, Yoshimura T, Shiroki T, Nagino K, Hanabata N, Funakubo A, Hirasawa D, Ohira T, Nakamura J, Nakamura T, Nakaya N, Matsumoto T, Fukuda S, Masamune A, Iijima KPrognostic Benefit of Additional Treatment After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma.Dig Dis Sci ( 2023) 68(5): 2050-2060PMID : 36445654
• Nasseri-Moghaddam S, Mousavian AH, Kasaeian A, Kanno T, Yuan Y, Ford AC, Moayyedi PWhat is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis.Clin Gastroenterol Hepatol ( 2023) 21(7): 1739-1749.e2PMID : 35738355
• Toya Y, Shimada T, Hamada K, Watanabe K, Nakamura J, Fukushi D, Hatta W, Shinkai H, Ito H, Matsuhashi T, Fujimori S, Iwai W, Hanabata N, Shiroki T, Sasaki Y, Fujishima Y, Tsuji T, Yorozu H, Yoshimura T, Horikawa Y, Takahashi Y, Takahashi H, Kondo Y, Fujiwara T, Mizugai H, Gonai T, Tatsuta T, Onochi K, Kudara N, Abe K, Ohira T, Horikawa Y, Ishihata R, Hikichi T, Satoh K, Takahashi F, Masamune A, Iijima K, Fukuda S, Matsumoto TPrediction model of 3-year survival after endoscopic submucosal dissection for early gastric cancer in elderly patients aged ≥ 85 years: EGC-2 model.J Cancer Res Clin Oncol ( 2023) 149(4): 1521-1530PMID : 35546359

2022年(24件)

• Okata T, Asanuma K, Nakagawa K, Hatta W, Koike T, Imatani A, Masamune AThe Impact of Duodenal Mucosal Vulnerability in the Development of Epigastric Pain Syndrome in Functional Dyspepsia.Int J Mol Sci ( 2022) 23(22):PMID : 36430426
• Asano N, Takeuchi A, Imatani A, Saito M, Jin X, Hatta W, Uno K, Koike T, Masamune AWnt Signaling and Aging of the Gastrointestinal Tract.Int J Mol Sci ( 2022) 23(20):PMID : 36293064
• Uno K, Koike T, Hatta W, Saito M, Tanabe M, Masamune ADevelopment of Advanced Imaging and Molecular Imaging for Barrett's Neoplasia.Diagnostics (Basel) ( 2022) 12(10):PMID : 36292126
• Odagiri H, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Kikuchi D, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Hoteya SBleeding following Endoscopic Submucosal Dissection for Early Gastric Cancer in Surgically Altered Stomach.Digestion ( 2022) 103(6): 428-437PMID : 36195054
• Toda S, Hatta W, Asanuma K, Asano N, Ono Y, Abe H, Ogata Y, Saito M, Kanno T, Jin X, Uno K, Koike T, Imatani A, Hamada S, Nakamura T, Nakaya N, Masamune ADecreased Expression of NRF2 Target Genes after Alcohol Exposure in the Background Esophageal Mucosa of Patients with Esophageal Squamous Cell Carcinoma.Tohoku J Exp Med ( 2022) 258(3): 195-206PMID : 36070895
• Hatta W, Koike T, Uno K, Asano N, Masamune AManagement of Superficial Esophageal Squamous Cell Carcinoma and Early Gastric Cancer following Non-Curative Endoscopic Resection.Cancers (Basel) ( 2022) 14(15):PMID : 35954421
• Koike T, Saito M, Ohara Y, Hatta W, Masamune ACurrent status of surveillance for Barrett's esophagus in Japan and the West.DEN open ( 2022) 2(1): e94PMID : 35898591
• Sugaya R, Kanno T, Yasaka H, Masu M, Otomo M, Koike TFeasibility of Support by Family Practitioners in Reducing Colorectal Cancer-Related Death among Outpatients Who Have Not Undergone Colorectal Cancer Screening.Diagnostics (Basel) ( 2022) 12(8):PMID : 35892492
• Kusano K, Uno K, Koike T, Miura S, Kume K, Nakahori M, Fujishima F, Ohtsuka H, Unno M, Masamune AA case of refractory esophageal stricture due to occult gastrinoma of the duodenum.Clin J Gastroenterol ( 2022) 15(5): 859-863PMID : 35788898
• Shimada T, Hatta W, Takahashi S, Koike T, Ohira T, Hikichi T, Toya Y, Tanaka I, Onozato Y, Hamada K, Fukushi D, Watanabe K, Kayaba S, Ito H, Mikami T, Oikawa T, Takahashi Y, Kondo Y, Yoshimura T, Shiroki T, Nagino K, Hanabata N, Funakubo A, Nakamura J, Matsumoto T, Iijima K, Fukuda S, Masamune A, Ito KCombined assessment of clinical and pathological prognostic factors for deciding treatment strategies for esophageal squamous cell carcinoma invading into the muscularis mucosa or submucosa after endoscopic submucosal dissection.Dig Endosc ( 2022) 34(7): 1382-1391PMID : 35702926
• Koizumi E, Goto O, Takizawa K, Mitsunaga Y, Hoteya S, Hatta W, Masamune A, Osawa S, Takeuchi H, Suzuki S, Omori J, Ikeda G, Habu T, Ishikawa Y, Kirita K, Noda H, Higuchi K, Onda T, Akimoto T, Akimoto N, Kaise M, Iwakiri KBilateral Risk Assessments of Surgery and Nonsurgery Contribute to Providing Optimal Management in Early Gastric Cancers after Noncurative Endoscopic Submucosal Dissection: A Multicenter Retrospective Study of 485 Patients.Digestion ( 2022) 103(4): 296-307PMID : 35512657
• Hatta W, Koike T, Abe H, Ogata Y, Saito M, Jin X, Kanno T, Uno K, Asano N, Imatani A, Masamune ARecent approach for preventing complications in upper gastrointestinal endoscopic submucosal dissection.DEN open ( 2022) 2(1): e60PMID : 35310735
• Endo H, Koike T, Obara N, Hatta W, Masamune ACommercially available novel device to prevent the diffusion of droplets from subjects undergoing esophagogastroduodenoscopy: A pilot study with its prototype.DEN open ( 2022) 2(1): e36PMID : 35310698
• Hayashi Y, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Miyake A, Fujishiro M, Masamune A, Takehara TThe degree of mucosal atrophy is associated with post-endoscopic submucosal dissection bleeding in early gastric cancer.J Gastroenterol Hepatol ( 2022) 37(5): 870-877PMID : 35132695
• Abe Y, Hatta W, Asonuma S, Koike T, Abe H, Ogata Y, Saito M, Jin X, Kanno T, Uno K, Asano N, Imatani A, Fujishima F, Sasano H, Masamune AParietal Cell Dysfunction: A Rare Cause of Gastric Neuroendocrine Neoplasm with Achlorhydria and Extreme Hypergastrinemia.Intern Med ( 2022) 61(16): 2441-2448PMID : 35110476
• Kanno T, Yuan Y, Tse F, Howden CW, Moayyedi P, Leontiadis GIProton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding.Cochrane Database Syst Rev ( 2022) 1 CD005415PMID : 34995368
• Watanabe K, Koizumi S, Shirane K, Tsuda H, Watanabe H, Tsuji T, Onochi K, Yamai K, Kusano C, Dohmen T, Horikawa Y, Ajimine T, Saito M, Koike T, Masamune A, Shimodaira Y, Matsuhashi T, Iijima KVisceral obesity is associated with an increased risk of developing esophago-gastric junctional adenocarcinoma in Japan: a population-based case-control study in Akita Prefecture.Esophagus ( 2022) 19(3): 477-485PMID : 34993674
• Fujiya T, Asanuma K, Koike T, Okata T, Saito M, Asano N, Imatani A, Masamune ANitric oxide could promote development of Barrett's esophagus by <i>S</i>-nitrosylation-induced inhibition of Rho-ROCK signaling in esophageal fibroblasts.Am J Physiol Gastrointest Liver Physiol ( 2022) 322(1): G107-G116PMID : 34786954
• Ogata Y, Hatta W, Ohara Y, Koike T, Abe H, Saito M, Jin X, Kanno T, Uno K, Asano N, Imatani A, Yamamura A, Tanaka N, Kamei T, Unno M, Nakamura T, Nakaya N, Masamune APredictors of early and late mortality after the treatment for early gastric cancers.Dig Endosc ( 2022) 34(4): 816-825PMID : 34662456
• Hatta W, Gotoda T, Koike T, Uno K, Asano N, Imatani A, Masamune AIs Additional Gastrectomy Required for Elderly Patients after Endoscopic Submucosal Dissection with Endoscopic Curability C-2 for Early Gastric Cancer?Digestion ( 2022) 103(1): 83-91PMID : 34638125
• Matsuhashi T, Fukuda S, Abe Y, Mikami T, Tatsuta T, Hikichi T, Nakamura J, Onozato Y, Hatta W, Masamune A, Ohyauchi M, Ito H, Hanabata N, Araki Y, Yanagita T, Imamura H, Tsuji T, Sugawara K, Horikawa Y, Ohara S, Kondo Y, Dohmen T, Iijima KNature and treatment outcomes of bleeding post-bulbar duodenal ulcers.Dig Endosc ( 2022) 34(5): 984-993PMID : 34609030
• Nagami Y, Hatta W, Tsuji Y, Yoshio T, Kakushima N, Hoteya S, Tsuji S, Fukunaga S, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Yoshida H, Fujishiro M, Masamune A, Fujiwara YAntithrombotics increase bleeding after endoscopic submucosal dissection for gastric cancer: Nationwide propensity score analysis.Dig Endosc ( 2022) 34(5): 974-983PMID : 34564863
• Yabuuchi Y, Hatta W, Tsuji Y, Yoshio T, Kakushima N, Hoteya S, Doyama H, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Ono HInfluence of hospital volume on bleeding after endoscopic submucosal dissection for early gastric cancer in Japan: a multicenter propensity score-matched analysis.Surg Endosc ( 2022) 36(6): 4004-4013PMID : 34494147
• Matsuhashi T, Fukuda S, Mikami T, Tatsuta T, Hikichi T, Nakamura J, Abe Y, Onozato Y, Hatta W, Masamune A, Ohyauchi M, Ito H, Hanabata N, Araki Y, Yanagita T, Imamura H, Tsuji T, Sugawara K, Horikawa Y, Ohara S, Kondo Y, Dohmen T, Iijima KEffects of anti-thrombotic drugs on all-cause mortality after upper gastrointestinal bleeding in Japan: A multicenter study with 2205 cases.Dig Endosc ( 2022) 34(1): 113-122PMID : 33615547

2021年(11件)

• Hatta W, Koike T, Ogata Y, Kondo Y, Ara N, Uno K, Asano N, Imatani A, Masamune AComparison of Magnifying Endoscopy with Blue Light Imaging and Narrow Band Imaging for Determining the Invasion Depth of Superficial Esophageal Squamous Cell Carcinoma by the Japanese Esophageal Society's Intrapapillary Capillary Loop Classification.Diagnostics (Basel) ( 2021) 11(11):PMID : 34829288
• Saito M, Koike T, Ohara Y, Nakagawa K, Kanno T, Jin X, Hatta W, Uno K, Asano N, Imatani A, Masamune ALinked-color Imaging May Help Improve the Visibility of Superficial Barrett's Esophageal Adenocarcinoma by Increasing the Color Difference.Intern Med ( 2021) 60(21): 3351-3358PMID : 34719622
• Sugimoto M, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Doyama H, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Murata M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Kawai TRisk Factors for Bleeding After Endoscopic Submucosal Dissection for Gastric Cancer in Elderly Patients Older Than 80 Years in Japan.Clin Transl Gastroenterol ( 2021) 12(9): e00404PMID : 34644281
• Matsuhashi T, Hatta W, Hikichi T, Fukuda S, Mikami T, Tatsuta T, Nakamura J, Abe Y, Onozato Y, Ogata Y, Masamune A, Ohyauchi M, Ito H, Hanabata N, Araki Y, Yanagita T, Imamura H, Tsuji T, Sugawara K, Horikawa Y, Ohara S, Kondo Y, Dohmen T, Kakuta Y, Nakamura T, Iijima KA simple prediction score for in-hospital mortality in patients with nonvariceal upper gastrointestinal bleeding.J Gastroenterol ( 2021) 56(8): 758-768PMID : 34143312
• Shiroma S, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Fujisaki JTiming of bleeding and thromboembolism associated with endoscopic submucosal dissection for gastric cancer in Japan.J Gastroenterol Hepatol ( 2021) 36(10): 2769-2777PMID : 33960518
• Hatta W, Koike T, Takahashi S, Shimada T, Hikichi T, Toya Y, Tanaka I, Onozato Y, Hamada K, Fukushi D, Watanabe K, Kayaba S, Ito H, Mikami T, Oikawa T, Takahashi Y, Kondo Y, Yoshimura T, Shiroki T, Nagino K, Hanabata N, Funakubo A, Hirasawa D, Ohira T, Nakamura J, Matsumoto T, Nakamura T, Nakaya N, Iijima K, Fukuda S, Masamune ARisk of metastatic recurrence after endoscopic resection for esophageal squamous cell carcinoma invading into the muscularis mucosa or submucosa: a multicenter retrospective study.J Gastroenterol ( 2021) PMID : 33881632
• Abe H, Hatta W, Ogata Y, Koike T, Saito M, Jin X, Nakagawa K, Kanno T, Uno K, Asano N, Imatani A, Nakamura T, Nakaya N, Tarasawa K, Fujimori K, Fushimi K, Masamune APrevention of delayed bleeding with vonoprazan in upper gastrointestinal endoscopic treatment.J Gastroenterol ( 2021) PMID : 33876324
• Abe H, Uno K, Tanaka N, Mizuma M, Hatta W, Asano N, Koike T, Imatani A, Unno M, Masamune AA rare case of penetration related to ischemic duodenitis after ventricular assist device implantation for dilated cardiomyopathy.Clin J Gastroenterol ( 2021) 14(4): 1186-1190PMID : 33763820
• Hashimoto M, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Hoteya S, Doyama H, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Fujishiro M, Masamune A, Ohira HRebleeding in patients with delayed bleeding after endoscopic submucosal dissection for early gastric cancer.Dig Endosc ( 2021) 33(7): 1120-1130PMID : 33539035
• Ogata Y, Hatta W, Koike T, Saito M, Jin X, Nakagawa K, Kanno T, Uno K, Asano N, Imatani A, Nakamura T, Nakaya N, Masamune APredictors of Early and Late Mortality after Endoscopic Resection for Esophageal Squamous Cell Carcinoma.Tohoku J Exp Med ( 2021) 253(1): 29-39PMID : 33441512
• Hatta W, Tsuji Y, Yoshio T, Kakushima N, Hoteya S, Doyama H, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Koike T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribasyashi S, Kiyotoki S, Mabe K, Nakamura T, Nakaya N, Fujishiro M, Masamune APrediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score.Gut ( 2021) 70(3): 476-484PMID : 32499390

2020年(18件)

• Fujiya T, Hatta W, Koike T, Ogata Y, Saito M, Jin X, Nakagawa K, Kanno T, Asanuma K, Uno K, Asano N, Imatani A, Fujishima F, Katoh N, Yoshinaga T, Masamune AA Rare Case of Localized Esophageal Amyloidosis.Intern Med ( 2020) PMID : 33281165
• Norita K, Koike T, Saito M, Shinkai H H, Ami R, Abe Y, Dairaku N, Inomata Y, Kayaba S, Ishiyama F, Oikawa T, Ohyauchi M, Ito H, Asonuma S, Hoshi T, Kato K, Ohara S, Shimodaira Y, Watanabe K, Shimosegawa T, Masamune A, Iijima KLong-term endoscopic surveillance for Barrett's esophagus in Japan: A multicenter prospective cohort study.Dig Endosc ( 2020) PMID : 33277694
• Takahashi Y, Hatta W, Koike T, Ogata Y, Fujiya T, Saito M, Jin X, Nakagawa K, Kanno T, Asanuma K, Uno K, Asano N, Imatani A, Fujishima F, Katoh N, Yoshinaga T, Masamune ALocalized Gastric Amyloidosis that Displayed Morphological Changes over 10 Years of Observation.Intern Med ( 2020) PMID : 32999220
• Saito M, Koike T, Abe Y, Nakagawa K, Kanno T, Jin X, Hatta W, Uno K, Asano N, Imatani A, Fujishima F, Masamune AA Case of the Development of Foveolar-type Gastric Adenocarcinoma during Maintenance Therapy of Vonoprazan for Reflux Esophagitis.Intern Med ( 2020) PMID : 32863366
• Endo H, Obara N, Watanabe T, Sanada S, Koike T, Masamune AUsing Polyethylene Glycol 3350 Plus Electrolytes in Constipated Hemodialysis Patients: A Case Series.Intern Med ( 2020) PMID : 32863362
• Sawada A, Itami H, Nakagawa K, Hirano S, Kitamura H, Nakata R, Takashima S, Abe Y, Saito M, Yazaki E, Kawamura O, Tanaka F, Takeuchi T, Koike T, Masamune A, Fujiwara Y, Higuchi K, Sifrim DSupragastric belching in Japan: lower prevalence and relevance for management of gastroesophageal reflux disease compared to United Kingdom.J Gastroenterol ( 2020) PMID : 32839926
• Norita K, Asanuma K, Koike T, Okata T, Fujiya T, Abe Y, Nakagawa K, Hatta W, Uno K, Nakamura T, Nakaya N, Asano N, Imatani A, Shimosegawa T, Masamune AImpaired Mucosal Integrity in Proximal Esophagus Is Involved in Development of Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease.Digestion ( 2020) 1-11PMID : 32784296
• Saito M, Asanuma K, Hatta W, Koike T, Hata T, Fujishima F, Furukawa T, Unno M, Masamune ADuodenal Obstruction Caused by the Long-term Recurrence of Appendiceal Goblet Cell Carcinoid.Intern Med ( 2020) PMID : 32759580
• Kikuchi H, Fukuda S, Koike T, Shimodaira Y, Watanabe K, Saito M, Nakagawa K, Hatta W, Masamune A, Iijima KAssociation of residual gastric acid secretion with persistent symptoms in gastroesophageal reflux disease patients receiving standard-dose proton pump inhibitor therapy.Esophagus ( 2020) PMID : 32737802
• Oriuchi M, Uno K, Fujishima F, Takeuchi A, Lee S, Hatta W, Asano N, Koike T, Imatani A, Masamune AA rare case of gastric squamous-cell carcinoma metastasized from the cervix.Clin J Gastroenterol ( 2020) PMID : 32712841
• Endo H, Koike T, Masamune ANovel device for preventing diffusion of aerosol droplets from subjects undergoing esophagogastroduodenoscopy during COVID-19 pandemic.Dig Endosc ( 2020) PMID : 32696996
• Akiyama J, Sumida J, Nakagawa K, Masamune A, Issariyakulkarn N, Patcharatrakul T, Shetler K, Kuribayashi S, Uraoka T, Triadafilopoulos GNew developments in esophageal function testing and esophageal manifestations of connective tissue disorders.Ann N Y Acad Sci ( 2020) PMID : 32627210
• Koike T, Masamune A[Relationship between lifestyle and esophageal disease].Nihon Shokakibyo Gakkai Zasshi ( 2020) 117(5): 365-374PMID : 32389908
• Lee S, Uno K, Fujishima F, Hatta W, Koike T, Aoki T, Tanaka N, Musha H, Kikuchi R, Masamune AGastric Duplication Cyst With Occult GIST Component.ACG Case Rep J ( 2020) 7(2): e00260PMID : 32309505
• Hatta W, Gotoda T, Kanno T, Yuan Y, Koike T, Moayyedi P, Masamune APrevalence and risk factors for lymph node metastasis after noncurative endoscopic resection for early gastric cancer: a systematic review and meta-analysis.J Gastroenterol ( 2020) PMID : 32277297
• Hatta W, Gotoda T, Masamune ANon-Curative Resection: Should Clinicians Consider Providing Additional Surgery for All Patients?Clin Endosc ( 2020) PMID : 32138464
• Abe Y, Koike T, Saito M, Okata T, Nakagawa K, Hatta W, Asanuma K, Uno K, Asano N, Imatani A, Masamune AThe Ameliorating Effect of Switching to Vonoprazan: A Novel Potassium-Competitive Acid Blocker in Patients with Proton Pump Inhibitor Refractory Non-Erosive Reflux Disease.Digestion ( 2020) 1-9PMID : 32062650
• Takahashi K, Asano N, Imatani A, Kondo Y, Saito M, Takeuchi A, Jin X, Saito M, Hatta W, Asanuma K, Uno K, Koike T, Masamune ASox2 induces tumorigenesis and angiogenesis of early stage esophagealsquamous cell carcinoma through secretion of Suprabasin.Carcinogenesis ( 2020) PMID : 32055838

2019年(15件)

• Hatta W, Gotoda T, Koike T, Masamune AThe management following endoscopic resection in elderly patients with early-stage upper gastrointestinal neoplasia.Dig Endosc ( 2019) PMID : 31802529
• Okata T, Uno K, Fujishima F, Saito M, Jin X, Hatta W, Asanuma K, Asano N, Koike T, Imatani A, Masamune ADifficult Preoperative Diagnosis of Lymphoepithelioma-Like Carcinoma of the Esophagus.ACG Case Rep J ( 2019) 6(8): e00163PMID : 31737702
• Nakagawa K, Koike T, Masamune A[The utility of high-resolution manometry for functional esophageal disorders].Nihon Shokakibyo Gakkai Zasshi ( 2019) 116(10): 780-787PMID : 31597876
• Hatta W, Gotoda T, Koike T, Masamune AA Recent Argument for the Use of Endoscopic Submucosal Dissection for Early Gastric Cancers.Gut Liver ( 2019) PMID : 31554392
• Hatta W, Gotoda T, Koike T, Masamune AHistory and future perspectives in Japanese guidelines for endoscopic resection of early gastric cancer.Dig Endosc ( 2019) PMID : 31529716
• Nakagawa K, Hara K, Fikree A, Siddiqi S, Woodland P, Masamune A, Aziz Q, Sifrim D, Yazaki EPatients with dyspepsia have impaired mucosal integrity both in the duodenum and jejunum: in vivo assessment of small bowel mucosal integrity using baseline impedance.J Gastroenterol ( 2019) PMID : 31468184
• Saito M, Koike T, Nakagawa K, Abe Y, Norita K, Kikuchi H, Kanno T, Hatta W, Ara N, Uno K, Asanuma K, Asano N, Imatani A, Shimosegawa T, Masamune AStrong Intra-Esophageal Reflux May Contribute to the Development of Barrett's Adenocarcinoma and Affect the Localization.Digestion ( 2019) 1-9PMID : 31412336
• Tsuchiya S, Matsumoto Y, Doman T, Fujiya T, Sugisawa J, Suda A, Sato K, Ikeda S, Shindo T, Kikuchi Y, Hao K, Takahashi J, Hatta W, Koike T, Masamune A, Saiki Y, Horiuchi H, Shimokawa HDisappearance of Angiodysplasia Following Transcatheter Aortic Valve Implantation in a Patient with Heyde's Syndrome: A Case Report and Review of the Literature.J Atheroscler Thromb ( 2019) PMID : 31378751
• Abe Y, Koike T, Saito M, Okata T, Norita K, Kikuchi H, Nakagawa K, Hatta W, Asanuma K, Uno K, Asano N, Imatani A, Shimosegawa T, Masamune AInfluence of the pH Value of Refluxate and Proximal Extent on Heartburn Perception in Patients with Proton Pump Inhibitor-Refractory Non-Erosive Reflux Disease.Digestion ( 2019) 1-7PMID : 31357199
• Hatta W, Gotoda T, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Nakamura T, Nakaya N, Shimosegawa T, Masamune AIs Additional Surgery Always Sufficient for Preventing Recurrence After Endoscopic Submucosal Dissection with Curability C-2 for Early Gastric Cancer?Ann Surg Oncol ( 2019) PMID : 31342376
• Takeuchi A, Hatta W, Koike T, Saito M, Jin X, Asanuma K, Uno K, Asano N, Imatani A, Fujishima F, Masamune AA Primary Barrett's Adenocarcinoma with a Squamous Cell Carcinoma Component.Intern Med ( 2019) PMID : 31118396
• Endo H, Koike T, Hatta W, Asanuma K, Uno K, Asano N, Imatani A, Watanabe M, Kato K, Masamune AEndoscopic Findings of Esophageal Adenosquamous Carcinoma Diagnosed by Endoscopic Mucosal Resection.Case Rep Gastroenterol ( 2019) 13(1): 144-152PMID : 31097930
• Esaki M, Hatta W, Shimosegawa T, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Gotoda TAge Affects Clinical Management after Noncurative Endoscopic Submucosal Dissection for Early Gastric Cancer.Dig Dis ( 2019) 1-11PMID : 31096243
• Hatta W, Koike T, Okata H, Hanzawa T, Saito M, Kondo Y, Ara N, Asanuma K, Uno K, Asano N, Imatani A, Iijima K, Nakamura T, Nakaya N, Masamune AContinuously liquid-sucking catheter attachment for the endoscope reduces the volume of liquid reflux to the mouth in esophageal endoscopic submucosal dissection.Dig Endosc ( 2019) PMID : 30861606
• Dohi O, Hatta W, Gotoda T, Naito Y, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Shimosegawa TLong-term outcomes after non-curative endoscopic submucosal dissection for early gastric cancer according to hospital volumes in Japan: a multicenter propensity-matched analysis.Surg Endosc ( 2019) PMID : 30805782

2018年(9件)

• Takizawa K, Hatta W, Gotoda T, Kawata N, Nakagawa M, Takahashi A, Esaki M, Mitoro A, Yamada S, Tanaka K, Matsuda M, Takada J, Oka S, Ito H, Ohnita K, Shimoda R, Hoteya S, Oyama T, Shimosegawa TRecurrence Patterns and Outcomes of Salvage Surgery in Cases of Non-Curative Endoscopic Submucosal Dissection without Additional Radical Surgery for Early Gastric Cancer.Digestion ( 2018) 99(1): 52-58PMID : 30554228
• Yamada S, Hatta W, Shimosegawa T, Takizawa K, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Nakaya N, Gotoda TDifferent risk factors between early and late cancer recurrences in patients without additional surgery after noncurative endoscopic submucosal dissection for early gastric cancer.Gastrointest Endosc ( 2018) PMID : 30465769
• Kanno T, Moayyedi PImipramine for functional dyspepsia: a 60-year journey.Lancet Gastroenterol Hepatol ( 2018) 3(12): 815-817PMID : 30361079
• Kondo Y, Hatta W, Koike T, Takahashi Y, Saito M, Kanno T, Asanuma K, Asano N, Imatani A, Masamune AThe Use of Higher Dose Steroids Increases the Risk of Rebleeding After Endoscopic Hemostasis for Peptic Ulcer Bleeding.Dig Dis Sci ( 2018) PMID : 30022453
• Miyahara K, Hatta W, Nakagawa M, Oyama T, Kawata N, Takahashi A, Yoshifuku Y, Hoteya S, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Shimosegawa TThe Role of an Undifferentiated Component in Submucosal Invasion and Submucosal Invasion Depth After Endoscopic Submucosal Dissection for Early Gastric Cancer.Digestion ( 2018) 98(3): 161-168PMID : 29870985
• Murata T, Asanuma K, Ara N, Iijima K, Hatta W, Hamada S, Asano N, Koike T, Imatani A, Masamune A, Shimosegawa TLeptin Aggravates Reflux Esophagitis by Increasing Tissue Levels of Macrophage Migration Inhibitory Factor in Rats.Tohoku J Exp Med ( 2018) 245(1): 45-53PMID : 29760351
• Takahashi Y, Uno K, Iijima K, Abe Y, Koike T, Asano N, Asanuma K, Shimosegawa TAcidic bile salts induces mucosal barrier dysfunction through <i>let-7a</i> reduction during gastric carcinogenesis after <i>Helicobacter pylori</i> eradication.Oncotarget ( 2018) 9(26): 18069-18083PMID : 29719591
• Minaga K, Watanabe T, Kamata K, Asano N, Kudo MNucleotide-binding oligomerization domain 1 and <i>Helicobacter pylori</i> infection: A review.World J Gastroenterol ( 2018) 24(16): 1725-1733PMID : 29713127
• Okata H, Hatta W, Iijima K, Asanuma K, Tsuruya A, Asano N, Koike T, Hamada S, Nakayama T, Masamune A, Shimosegawa TDetection of Acetaldehyde in the Esophageal Tissue among Healthy Male Subjects after Ethanol Drinking and Subsequent L-Cysteine Intake.Tohoku J Exp Med ( 2018) 244(4): 317-325PMID : 29681559

2017年(12件)

• Torihata Y, Asanuma K, Iijima K, Mikami T, Hamada S, Asano N, Koike T, Imatani A, Masamune A, Shimosegawa TEstrogen-Dependent Nrf2 Expression Protects Against Reflux-Induced Esophagitis.Dig Dis Sci ( 2017) PMID : 29282639
• Hanzawa T, Matsunaga T, Koike T, Kanno A, Masamune A, Iijima K, Shimosegawa T, Haga YA new manometry device for evaluating the sphincter of Oddi using a fiber-optic pressure sensor.Minim Invasive Ther Allied Technol ( 2017) 1-7PMID : 29233059
• Watanabe T, Asano N, Kudo M, Strober WNucleotide-binding oligomerization domain 1 and gastrointestinal disorders.Proc Jpn Acad Ser B Phys Biol Sci ( 2017) 93(8): 578-599PMID : 29021509
• Hatta W, Gotoda T, Oyama T, Kawata N, Takahashi A, Yoshifuku Y, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Yamanouchi K, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Hayashi Y, Nakamura T, Nakaya N, Shimosegawa TIs the eCura system useful for selecting patients who require radical surgery after noncurative endoscopic submucosal dissection for early gastric cancer? A comparative study.Gastric Cancer ( 2017) PMID : 28983696
• Suzuki S, Gotoda T, Hatta W, Oyama T, Kawata N, Takahashi A, Yoshifuku Y, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Yamanouchi K, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Hayashi Y, Shimosegawa TSurvival Benefit of Additional Surgery After Non-curative Endoscopic Submucosal Dissection for Early Gastric Cancer: A Propensity Score Matching Analysis.Ann Surg Oncol ( 2017) PMID : 28795364
• Uno K, Koike T, Takahashi S, Komazawa D, Shimosegawa TManagement of aorto-esophageal fistula secondary after thoracic endovascular aortic repair: a review of literature.Clin J Gastroenterol ( 2017) PMID : 28766283
• Takahashi K, Hatta W, Koike T, Kanno T, Ara N, Asanuma K, Asano N, Imatani A, Fujishima F, Sasano H, Shimosegawa TThe slow progressive nature of duodenal neuroendocrine tumor: a case report of long-term observation over 14 years.Clin J Gastroenterol ( 2017) PMID : 28664383
• Ito H, Gotoda T, Oyama T, Kawata N, Takahashi A, Yoshifuku Y, Hoteya S, Nakagawa M, Hatta W, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Hayashi Y, Nakaya N, Nakamura T, Shimosegawa TLong-term oncological outcomes of submucosal manipulation during non-curative endoscopic submucosal dissection for submucosal invasive gastric cancer: a multicenter retrospective study in Japan.Surg Endosc ( 2017) PMID : 28639037
• Uno K, Koike T, Kusaka G, Takahashi Y, Ara N, Shimosegawa TRisk of metachronous recurrence after endoscopic submucosal dissection of esophageal squamous cell carcinoma.Dis Esophagus ( 2017) 30(6): 1-8PMID : 28475742
• Hatta W, Gotoda T, Oyama T, Kawata N, Takahashi A, Yoshifuku Y, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Yamanouchi K, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Hayashi Y, Nakaya N, Nakamura T, Shimosegawa TA Scoring System to Stratify Curability after Endoscopic Submucosal Dissection for Early Gastric Cancer: Am J Gastroenterol ( 2017) PMID : 28397873
• Hatta W, Koike T, Iijima K, Asanuma K, Asano N, Musha H, Inomata Y, Sano T, Endo H, Ikehata A, Horii T, Ohyauchi M, Yokosawa S, Kasajima A, Fujishima F, Sasano H, Nakaya N, Nakamura T, Shimosegawa TThe Risk Factors for Metastasis in Non-Ampullary Duodenal Neuroendocrine Tumors Measuring 20 mm or Less in Diameter.Digestion ( 2017) 95(3): 201-209PMID : 28315861
• Shiroki T, Yokoyama M, Tanuma N, Maejima R, Tamai K, Yamaguchi K, Oikawa T, Noguchi T, Miura K, Fujiya T, Shima H, Sato I, Murata-Kamiya N, Hatakeyama M, Iijima K, Shimosegawa T, Satoh KThe enhanced expression of PKM2 is involved in the gastric cancer development via regulating cancer specific metabolism.Cancer Sci ( 2017) PMID : 28235245

2016年(17件)

• Uno K, Iijima K, Abe Y, Koike T, Takahashi Y, Ara N, Shimosegawa TUsefulness of Endoscopic Imaging to Visualize Regional Alterations in Acid Secretion of Noncancerous Gastric Mucosa after <i>Helicobacter pylori</i> Eradication.J Gastric Cancer ( 2016) 16(3): 152-160PMID : 27752392
• Maejima R, Tamai K, Shiroki T, Yokoyama M, Shibuya R, Nakamura M, Yamaguchi K, Abue M, Oikawa T, Noguchi T, Miura K, Fujiya T, Sato I, Iijima K, Shimosegawa T, Tanaka N, Satoh KEnhanced expression of semaphorin 3E is involved in the gastric cancer development.Int J Oncol ( 2016) PMID : 27572291
• Ami R, Hatta W, Iijima K, Koike T, Ohkata H, Kondo Y, Ara N, Asanuma K, Asano N, Imatani A, Shimosegawa TFactors Associated With Metachronous Gastric Cancer Development After Endoscopic Submucosal Dissection for Early Gastric Cancer.J Clin Gastroenterol ( 2016) PMID : 27505404
• Konishi H, Asano N, Imatani A, Kimura O, Kondo Y, Jin X, Kanno T, Hatta W, Ara N, Asanuma K, Koike T, Shimosegawa TNotch1 directly induced CD133 expression in human diffuse type gastric cancers.Oncotarget ( 2016) PMID : 27489358
• Iijima K, Koike T, Abe Y, Ohara S, Shimosegawa TA Chronological Increase in Gastric Acid Secretion from 1995 to 2014 in Young Japanese Healthy Volunteers under the Age of 40 Years Old.Tohoku J Exp Med ( 2016) 239(3): 237-41PMID : 27440759
• Hatta W, Gotoda T, Oyama T, Kawata N, Takahashi A, Yoshifuku Y, Hoteya S, Nakamura K, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Hayashi Y, Nakamura T, Shimosegawa TIs radical surgery necessary in all patients who do not meet the curative criteria for endoscopic submucosal dissection in early gastric cancer? A multi-center retrospective study in Japan.J Gastroenterol ( 2016) PMID : 27098174
• Thanan R, Ma N, Hiraku Y, Iijima K, Koike T, Shimosegawa T, Murata M, Kawanishi SDNA Damage in CD133-Positive Cells in Barrett's Esophagus and Esophageal Adenocarcinoma.Mediators Inflamm ( 2016) PMID : 27069317
• Uno K, Iijima K, Shimosegawa TGastric cancer development after the successful eradication of Helicobacter pylori.World J Gastrointest Oncol ( 2016) 8(3): 271-81PMID : 26989462
• Kusaka G, Uno K, Iijima K, Shimosegawa TRole of nitric oxide in the pathogenesis of Barrett's-associated carcinogenesis.World J Gastrointest Pathophysiol ( 2016) 7(1): 131-7PMID : 26909236
• Kanno T, Iijima K, Abe Y, Yagi M, Asonuma S, Ohyauchi M, Ito H, Koike T, Shimosegawa THelicobacter pylori-negative and nonsteroidal anti-inflammatory drugs-negative idiopathic peptic ulcers show refractoriness and high recurrence incidence; multicenter follow-up study of peptic ulcers in Japan.Dig Endosc ( 2016) PMID : 26866510
• Asanuma K, Iijima K, Shimosegawa TGender difference in gastro-esophageal reflux diseases.World J Gastroenterol ( 2016) 22(5): 1800-1810PMID : 26855539
• Iijima K, Kanno T, Abe Y, Yagi M, Asonuma S, Ohyauchi M, Ito H, Koike T, Shimosegawa TPreferential location of idiopathic peptic ulcers.Scand J Gastroenterol ( 2016) 1-6PMID : 26854021
• Asano N, Imatani A, Watanabe T, Fushiya J, Kondo Y, Jin X, Ara N, Uno K, Iijima K, Koike T, Strober W, Shimosegawa TCdx2 expression and intestinal metaplasia induced by H. pylori infection of gastric cells is regulated by NOD1-mediated innate immune responses.Cancer Res ( 2016) PMID : 26759244
• Honda J, Iijima K, Asanuma K, Ara N, Shiroki T, Kondo Y, Hatta W, Uno K, Asano N, Koike T, Shimosegawa TEstrogen Enhances Esophageal Barrier Function by Potentiating Occludin Expression.Dig Dis Sci ( 2016) 61(4): 1028-38PMID : 26660903
• Maejima R, Uno K, Iijima K, Fujishima F, Noguchi T, Ara N, Asano N, Koike T, Imatani A, Shimosegawa TA Japanese case of lymphocytic esophagitis.Dig Endosc ( 2016) 28(4): 476-480PMID : 26589889
• Hatta W, Uno K, Koike T, Ara N, Asano N, Iijima K, Imatani A, Fujishima F, Shimosegawa TFeasibility of optical coherence tomography for the evaluation of Barrett's mucosa buried underneath esophageal squamous epithelium.Dig Endosc ( 2016) 28(4): 427-433PMID : 26583560
• Asanuma K, Huo X, Agoston A, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Wang DH, Iijima K, Shimosegawa T, Odze RD, Spechler SJ, Souza RFIn oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression.Gut ( 2016) 65(9): 1416-26PMID : 25986942

2015年(15件)

• Nakagawa K, Koike T, Iijima K, Saito M, Kikuchi H, Hatta W, Ara N, Uno K, Asano N, Shimosegawa TCharacteristics of symptomatic reflux episodes in Japanese proton pump inhibitor-refractory non-erosive reflux disease patients.World J Gastroenterol ( 2015) 21(47): 13352-9PMID : 26715820
• Iijima K, Shimosegawa TRisk Factors for Upper GI Damage in Low-Dose Aspirin Users and the Interaction Between H. pylori Infection and Low-Dose Aspirin Use.Curr Pharm Des ( 2015) 21(35): 5056-65PMID : 26369687
• Uno K, Koike T, Shimosegawa TRecent development of optical coherence tomography for preoperative diagnosis of esophageal malignancies.World J Gastrointest Endosc ( 2015) 7(9): 872-80PMID : 26240688
• Asano N, Iijima K, Koike T, Imatani A, Shimosegawa THelicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphomas: A review.World J Gastroenterol ( 2015) 21(26): 8014-20PMID : 26185372
• Iijima K, Shimosegawa TGeographic differences in low-dose aspirin-associated gastroduodenal mucosal injury.World J Gastroenterol ( 2015) 21(25): 7709-17PMID : 26167071
• Uno K, Iijima K, Koike T, Shimosegawa TUseful strategies to prevent severe stricture after endoscopic submucosal dissection for superficial esophageal neoplasm.World J Gastroenterol ( 2015) 21(23): 7120-33PMID : 26109798
• Iijima K, Koike T, Shimosegawa TReflux esophagitis triggered after Helicobacter pylori eradication: a noteworthy demerit of eradication therapy among the Japanese?Front Microbiol ( 2015) 6 566PMID : 26106373
• Maejima R, Iijima K, Kaihovaara P, Hatta W, Koike T, Imatani A, Shimosegawa T, Salaspuro MEffects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration.PLoS One ( 2015) 10(4): e0120397PMID : 25831092
• Maejima R, Koike T, Nakagawa K, Iijima K, Shimosegawa TEsomeprazole inhibits the pentagastrin-stimulated secretion of gastric acid in healthy Japanese volunteers.Tohoku J Exp Med ( 2015) 235(3): 249-53PMID : 25786769
• Hatta W, Iijima K, Koike T, Kondo Y, Ara N, Asanuma K, Uno K, Asano N, Imatani A, Shimosegawa TEndoscopic findings for predicting gastric acid secretion status.Dig Endosc ( 2015) 27(5): 582-9PMID : 25556402
• Kanno T, Iijima K, Abe Y, Yagi M, Asonuma S, Ohyauchi M, Ito H, Koike T, Shimosegawa TA multicenter prospective study on the prevalence of Helicobacter pylori-negative and nonsteroidal anti-inflammatory drugs-negative idiopathic peptic ulcers in Japan.J Gastroenterol Hepatol ( 2015) 30(5): 842-8PMID : 25532720
• Iijima K, Koike T, Abe Y, Ohara S, Nakaya N, Shimosegawa TTime series analysis of gastric acid secretion over a 20-year period in normal Japanese men.J Gastroenterol ( 2015) 50(8): 853-61PMID : 25528645
• Ara N, Iijima K, Maejima R, Kondo Y, Kusaka G, Hatta W, Uno K, Asano N, Koike T, Imatani A, Shimosegawa TProspective analysis of risk for bleeding after endoscopic biopsy without cessation of antithrombotics in Japan.Dig Endosc ( 2015) 27(4): 458-64PMID : 25425518
• Maejima R, Iijima K, Koike T, Ara N, Uno K, Hatta W, Ogawa T, Watanabe K, Katori Y, Shimosegawa TEndoscopic balloon dilatation for pharyngo-upper esophageal stricture after treatment of head and neck cancer.Dig Endosc ( 2015) 27(3): 310-6PMID : 25115575
• Kanno T, Iijima K, Koike T, Abe Y, Shimada N, Hoshi T, Sano N, Ohyauchi M, Ito H, Atsumi T, Konishi H, Asonuma S, Shimosegawa TAccommodation in a refugee shelter as a risk factor for peptic ulcer bleeding after the Great East Japan Earthquake: a case-control study of 329 patients.J Gastroenterol ( 2015) 50(1): 31-40PMID : 24531834

2014年(11件)

• Shinkai H, Iijima K, Koike T, Abe Y, Dairaku N, Inomata Y, Kayaba S, Ishiyama F, Oikawa T, Ohyauchi M, Ito H, Asonuma S, Hoshi T, Kato K, Ohara S, Shimosegawa TAssociation between the body mass index and the risk of Barrett's esophagus in Japan.Digestion ( 2014) 90(1): 1-9PMID : 25074386
• Strober W, Asano N, Fuss I, Kitani A, Watanabe TCellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohn's disease.Immunol Rev ( 2014) 260(1): 249-60PMID : 24942694
• Iijima K, Shimosegawa TInvolvement of luminal nitric oxide in the pathogenesis of the gastroesophageal reflux disease spectrum.J Gastroenterol Hepatol ( 2014) 29(5): 898-905PMID : 24863184
• Uno K, Kato K, Shimosegawa TNovel role of toll-like receptors in Helicobacter pylori - induced gastric malignancy.World J Gastroenterol ( 2014) 20(18): 5244-51PMID : 24833854
• Iijima K, Koike T, Abe Y, Shimosegawa TCutoff serum pepsinogen values for predicting gastric acid secretion status.Tohoku J Exp Med ( 2014) 232(4): 293-300PMID : 24717778
• Watanabe T, Asano N, Meng G, Yamashita K, Arai Y, Sakurai T, Kudo M, Fuss IJ, Kitani A, Shimosegawa T, Chiba T, Strober WNOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6.Mucosal Immunol ( 2014) 7(6): 1312-25PMID : 24670424
• Shinkai H, Iijima K, Koike T, Nakagawa K, Maejima R, Endo H, Ara N, Asano N, Imatani A, Ohara S, Shimosegawa TCalcium carbonate breath test for non-invasive estimation of gastric acid secretion.Tohoku J Exp Med ( 2014) 232(4): 255-61PMID : 24670370
• Iijima K, Kanno T, Koike T, Shimosegawa THelicobacter pylori-negative, non-steroidal anti-inflammatory drug: negative idiopathic ulcers in Asia.World J Gastroenterol ( 2014) 20(3): 706-13PMID : 24574744
• Nakagawa K, Koike T, Iijima K, Shinkai H, Hatta W, Endo H, Ara N, Uno K, Asano N, Imatani A, Shimosegawa TComparison of the long-term outcomes of endoscopic resection for superficial squamous cell carcinoma and adenocarcinoma of the esophagus in Japan.Am J Gastroenterol ( 2014) 109(3): 348-56PMID : 24394751
• Ara N, Iijima K, Honda J, Iwabuchi T, Hatta W, Endo H, Koike T, Kimura O, Kondo Y, Yuki T, Shimosegawa TEndoscopically proven case of rapid esophagogastric variceal progression and rupture as a result of portal hypertension with liver sarcoidosis.Dig Endosc ( 2014) 26(6): 745-8PMID : 24354353
• Abe Y, Iijima K, Ohara S, Koike T, Kikuchi R, Kato K, Shibuya D, Inomata Y, Oikawa K, Ueno YLocalized esophageal eosinophilia: Is it an early manifestation of eosinophilic esophagitis or a subtype of gastroesophageal reflux disease?Dig Endosc ( 2014) 26(3): 337-43PMID : 23895772

2013年(11件)

• Endo H, Shiroki T, Nakagawa T, Yokoyama M, Tamai K, Yamanami H, Fujiya T, Sato I, Yamaguchi K, Tanaka N, Iijima K, Shimosegawa T, Sugamura K, Satoh KEnhanced expression of long non-coding RNA HOTAIR is associated with the development of gastric cancer.PLoS One ( 2013) 8(10): e77070PMID : 24130837
• Iwabuchi T, Iijima K, Ara N, Koike T, Shinkai H, Ichikawa T, Kamata Y, Ishihara K, Shimosegawa TIncreased gastric mucus secretion alleviates non-steroidal anti-inflammatory drug-induced abdominal pain.Tohoku J Exp Med ( 2013) 231(1): 29-36PMID : 24005244
• Iijima K, Iwabuchi T, Ara N, Koike T, Shinkai H, Kamata Y, Ichikawa T, Ishihara K, Shimosegawa TReactive increase in gastric mucus secretion is an adaptive defense mechanism against low-dose aspirin-induced gastropathy.Dig Dis Sci ( 2013) 58(8): 2266-74PMID : 23649375
• Koike T, Endo H, Nakagawa K, Iijima K, Shimosegawa TBarrett's esophageal cancer in which magnifying narrow-band imaging was useful for diagnosing extension under the squamous epithelium.Dig Endosc ( 2013) 25 Suppl 2 181-3PMID : 23617674
• Koike T, Nakagawa K, Iijima K, Shimosegawa TEndoscopic resection (endoscopic submucosal dissection/endoscopic mucosal resection) for superficial Barrett's esophageal cancer.Dig Endosc ( 2013) 25 Suppl 1 20-8PMID : 23480400
• Jin X, Koike T, Chiba T, Kondo Y, Ara N, Uno K, Asano N, Iijima K, Imatani A, Watanabe M, Shirane A, Shimosegawa TCollagenous gastritis.Dig Endosc ( 2013) 25(5): 547-9PMID : 23363075
• Kanno T, Iijima K, Abe Y, Koike T, Shimada N, Hoshi T, Sano N, Ohyauchi M, Ito H, Atsumi T, Konishi H, Asonuma S, Shimosegawa THemorrhagic ulcers after Great East Japan Earthquake and Tsunami: features of post-disaster hemorrhagic ulcers.Digestion ( 2013) 87(1): 40-6PMID : 23343968
• Ara N, Uno K, Iijima K, Koike T, Asano N, Shimosegawa TSerious laryngeal edema during endoscopic resection for squamous cell carcinoma of the esophagus.Endoscopy ( 2013) 45(4): 313-5PMID : 23296362
• Kanno T, Iijima K, Abe Y, Koike T, Shimada N, Hoshi T, Sano N, Ohyauchi M, Ito H, Atsumi T, Konishi H, Asonuma S, Shimosegawa TPeptic ulcers after the Great East Japan earthquake and tsunami: possible existence of psychosocial stress ulcers in humans.J Gastroenterol ( 2013) 48(4): 483-90PMID : 23053423
• Iwai W, Abe Y, Iijima K, Koike T, Uno K, Asano N, Imatani A, Shimosegawa TGastric hypochlorhydria is associated with an exacerbation of dyspeptic symptoms in female patients.J Gastroenterol ( 2013) 48(2): 214-21PMID : 22829345
• Masaka T, Iijima K, Endo H, Asanuma K, Ara N, Ishiyama F, Asano N, Koike T, Imatani A, Shimosegawa TGender differences in oesophageal mucosal injury in a reflux oesophagitis model of rats.Gut ( 2013) 62(1): 6-14PMID : 22287598

2012年(12件)

• Asano N, Iijima K, Terai S, Jin X, Ara N, Chiba T, Fushiya J, Koike T, Imatani A, Shimosegawa TEradication therapy is effective for Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma.Tohoku J Exp Med ( 2012) 228(3): 223-7PMID : 23076291
• Uno K, Iijima K, Koike T, Abe Y, Asano N, Ara N, Shimosegawa TA pilot study of scheduled endoscopic balloon dilation with oral agent tranilast to improve the efficacy of stricture dilation after endoscopic submucosal dissection of the esophagus.J Clin Gastroenterol ( 2012) 46(9): e76-82PMID : 22955264
• Oikawa T, Asano N, Imatani A, Ohyauchi M, Fushiya J, Kondo Y, Abe Y, Koike T, Iijima K, Shimosegawa TGene polymorphisms of NOD1 and interleukin-8 influence the susceptibility to erosive esophagitis in Helicobacter pylori infected Japanese population.Hum Immunol ( 2012) 73(11): 1184-9PMID : 22902391
• Hatta W, Uno K, Koike T, Iijima K, Asano N, Imatani A, Shimosegawa TA prospective comparative study of optical coherence tomography and EUS for tumor staging of superficial esophageal squamous cell carcinoma.Gastrointest Endosc ( 2012) 76(3): 548-55PMID : 22898413
• Uno K, Iijima K, Koike T, Abe Y, Asano N, Yokosawa S, Imatani A, Shimosegawa TEndoscopic submucosal dissection combined with endoscopic injection sclerotherapy for early gastric cancer on gastric fundal varices.Surg Laparosc Endosc Percutan Tech ( 2012) 22(4): e226-9PMID : 22874708
• Kusaka G, Uno K, Iijima K, Endo H, Asano N, Koike T, Imatani A, Shimosegawa TThe role of nitric oxide in the induction of caudal-type homeobox 2 through epidermal growth factor receptor in the development of Barrett's esophagus.Scand J Gastroenterol ( 2012) 47(10): 1148-58PMID : 22834965
• Chiba T, Iijima K, Koike T, Uno K, Asano N, Shimosegawa TA case of severe esophageal intramural pseudodiverticulosis whose symptoms were ameliorated by oral administration of anti-fungal medicine.Case Rep Gastroenterol ( 2012) 6(1): 103-10PMID : 22619654
• Iijima K, Ara N, Abe Y, Koike T, Iwabuchi T, Shinkai H, Uno K, Endo H, Asano N, Shimosegawa TBiphasic effects of H. pylori infection on low-dose aspirin-induced gastropathy depending on the gastric acid secretion level.J Gastroenterol ( 2012) 47(12): 1290-7PMID : 22549566
• Thanan R, Ma N, Iijima K, Abe Y, Koike T, Shimosegawa T, Pinlaor S, Hiraku Y, Oikawa S, Murata M, Kawanishi SProton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression.Biochem Biophys Res Commun ( 2012) 421(2): 280-5PMID : 22503981
• Iijima K, Abe Y, Koike T, Uno K, Endo H, Hatta W, Asano N, Asanuma K, Imatani A, Shimosegawa TGastric cancers emerging after H. pylori eradication arise exclusively from non-acid-secreting areas.Tohoku J Exp Med ( 2012) 226(1): 45-53PMID : 22186036
• Iijima K, Ara N, Abe Y, Koike T, Iwai W, Iwabuchi T, Ichikawa T, Kamata Y, Ishihara K, Shimosegawa TAssociation of gastric acid and mucus secretion level with low-dose aspirin-induced gastropathy.J Gastroenterol ( 2012) 47(2): 150-8PMID : 22038552
• Nakamura S, Sugiyama T, Matsumoto T, Iijima K, Ono S, Tajika M, Tari A, Kitadai Y, Matsumoto H, Nagaya T, Kamoshida T, Watanabe N, Chiba T, Origasa H, Asaka MLong-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori: a multicentre cohort follow-up study of 420 patients in Japan.Gut ( 2012) 61(4): 507-13PMID : 21890816

2011年(11件)

• Uno K, Iijima K, Hatta W, Koike T, Abe Y, Asano N, Kusaka G, Shimosegawa TDirect measurement of gastroesophageal reflux episodes in patients with squamous cell carcinoma by 24-h pH-impedance monitoring.Am J Gastroenterol ( 2011) 106(11): 1923-9PMID : 21931379
• Abe Y, Koike T, Iijima K, Imatani A, Ishida K, Yuki T, Miyata G, Shimosegawa TEsophageal Adenocarcinoma Developing after Eradication of Helicobacter pylori.Case Rep Gastroenterol ( 2011) 5(2): 355-60PMID : 21769287
• Uno K, Kato K, Kusaka G, Asano N, Iijima K, Shimosegawa TThe balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas.Mol Carcinog ( 2011) 50(10): 781-90PMID : 21751261
• Asano N, Iijima K, Terai S, Uno K, Endo H, Koike T, Iwai W, Iwabuchi T, Hatta W, Abe Y, Imatani A, Shimosegawa TSignet Ring Cell Gastric Cancer Occurring after Radiation Therapy for Helicobacter pylori-Uninfected Mucosa-Associated Lymphoid Tissue Lymphoma.Case Rep Gastroenterol ( 2011) 5(2): 325-9PMID : 21712948
• Yamamoto J, Fujishima F, Ichinohasama R, Imatani A, Asano N, Harigae HA case of benign natural killer cell proliferative disorder of the stomach (gastric manifestation of natural killer cell lymphomatoid gastroenteropathy) mimicking extranodal natural killer/T-cell lymphoma.Leuk Lymphoma ( 2011) 52(9): 1803-5PMID : 21649544
• Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober WActivation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection.Gut Microbes ( 2011) 2(1): 61-5PMID : 21637021
• Horii T, Koike T, Abe Y, Kikuchi R, Unakami H, Iijima K, Imatani A, Ohara S, Shimosegawa TTwo distinct types of cancer of different origin may be mixed in gastroesophageal junction adenocarcinomas in Japan: evidence from direct evaluation of gastric acid secretion.Scand J Gastroenterol ( 2011) 46(6): 710-9PMID : 21446884
• Iijima K, Ara N, Abe Y, Koike T, Iwai W, Uno K, Asano N, Imatani A, Ohara S, Shimosegawa TGastric acid secretion level modulates the association between Helicobacter pylori infection and low-dose aspirin-induced gastropathy.J Gastroenterol ( 2011) 46(5): 612-9PMID : 21359520
• Kikuchi R, Abe Y, Iijima K, Koike T, Ara N, Uno K, Asanuma K, Asano N, Imatani A, Shimosegawa TLow serum levels of pepsinogen and gastrin 17 are predictive of extensive gastric atrophy with high-risk of early gastric cancer.Tohoku J Exp Med ( 2011) 223(1): 35-44PMID : 21222340
• Kawamura M, Abe S, Oikawa K, Terai S, Saito M, Shibuya D, Kato K, Inomata Y, Ohara S, Shimosegawa TMagnifying endoscopic findings of the surface structure of non-cancerous mucosa surrounding differentiated and undifferentiated gastric carcinoma.Dig Endosc ( 2011) 23(1): 37-42PMID : 21198915
• Abe Y, Iijima K, Ohara S, Koike T, Ara N, Uno K, Asano N, Imatani A, Kato K, Shibuya D, Shimosegawa TA Japanese case series of 12 patients with esophageal eosinophilia.J Gastroenterol ( 2011) 46(1): 25-30PMID : 20686904

2010年(7件)

• Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober WNOD1-Mediated Mucosal Host Defense against Helicobacter pylori.Int J Inflam ( 2010) 2010 476482PMID : 21152124
• Kobayashi S, Abe Y, Tashiro M, Koike T, Iijima K, Imatani A, Ohara S, Watanabe S, Fukudo S, Shimosegawa TBrain activity following esophageal acid infusion using positron emission tomography.World J Gastroenterol ( 2010) 16(43): 5481-9PMID : 21086568
• Oikawa T, Iijima K, Koike T, Uno K, Horii T, Iwai W, Abe Y, Asano N, Imatani A, Shimosegawa TDeficient aldehyde dehydrogenase 2 is associated with increased risk for esophageal squamous cell carcinoma in the presence of gastric hypochlorhydria.Scand J Gastroenterol ( 2010) 45(11): 1338-44PMID : 20521872
• Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober WNOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.J Clin Invest ( 2010) 120(5): 1645-62PMID : 20389019
• Hatta W, Uno K, Koike T, Yokosawa S, Iijima K, Imatani A, Shimosegawa TOptical coherence tomography for the staging of tumor infiltration in superficial esophageal squamous cell carcinoma.Gastrointest Endosc ( 2010) 71(6): 899-906PMID : 20304395
• Endo H, Iijima K, Asanuma K, Ara N, Ito H, Asano N, Uno K, Koike T, Imatani A, Shimosegawa TExogenous luminal nitric oxide exposure accelerates columnar transformation of rat esophagus.Int J Cancer ( 2010) 127(9): 2009-19PMID : 20131319
• Iijima K, Koike T, Abe Y, Yamagishi H, Ara N, Asanuma K, Uno K, Imatani A, Nakaya N, Ohara S, Shimosegawa TGastric hyposecretion in esophageal squamous-cell carcinomas.Dig Dis Sci ( 2010) 55(5): 1349-55PMID : 19513836

2009年(11件)

• Koike T, Ohara S, Shimosegawa TRole of gastric acid secretion in the pathogenesis of Barrett's esophageal cancer in a Japanese population.Clin J Gastroenterol ( 2009) 2(3): 143-8PMID : 26192284
• Yokosawa S, Koike T, Kitagawa Y, Hatta W, Uno K, Abe Y, Iijima K, Imatani A, Ohara S, Shimosegawa TIdentification of the layered morphology of the esophageal wall by optical coherence tomography.World J Gastroenterol ( 2009) 15(35): 4402-9PMID : 19764091
• Yamagishi H, Koike T, Ohara S, Abe Y, Iijima K, Imatani A, Kato K, Shibuya D, Aida S, Shimosegawa TClinical characteristics of gastroesophageal reflux disease in Japan.Hepatogastroenterology ( 2009) 56(93): 1032-4PMID : 19760935
• Asonuma S, Imatani A, Asano N, Oikawa T, Konishi H, Iijima K, Koike T, Ohara S, Shimosegawa THelicobacter pylori induces gastric mucosal intestinal metaplasia through the inhibition of interleukin-4-mediated HMG box protein Sox2 expression.Am J Physiol Gastrointest Liver Physiol ( 2009) 297(2): G312-22PMID : 19520737
• Iijima K, Koike T, Abe Y, Ara N, Uno K, Imatani A, Ohara S, Shimosegawa TAlteration of correlation between serum pepsinogen concentrations and gastric acid secretion after H. pylori eradication.J Gastroenterol ( 2009) 44(8): 819-25PMID : 19440811
• Terai S, Iijima K, Asanuma K, Ara N, Uno K, Abe Y, Koike T, Imatani A, Ohara S, Shimosegawa TLack of modulation of gastric emptying by dietary nitrate in healthy volunteers.Tohoku J Exp Med ( 2009) 218(1): 73-9PMID : 19398876
• Iijima K, Abe Y, Kikuchi R, Koike T, Ohara S, Sipponen P, Shimosegawa TSerum biomarker tests are useful in delineating between patients with gastric atrophy and normal, healthy stomach.World J Gastroenterol ( 2009) 15(7): 853-9PMID : 19230047
• Abe Y, Iijima K, Koike T, Asanuma K, Imatani A, Ohara S, Shimosegawa TBarrett's esophagus is characterized by the absence of Helicobacter pylori infection and high levels of serum pepsinogen I concentration in Japan.J Gastroenterol Hepatol ( 2009) 24(1): 129-34PMID : 19196398
• Ishiyama F, Iijima K, Asanuma K, Ara N, Yoshitake J, Abe Y, Koike T, Imatani A, Ohara S, Shimosegawa TExogenous luminal nitric oxide exacerbates esophagus tissue damage in a reflux esophagitis model of rats.Scand J Gastroenterol ( 2009) 44(5): 527-37PMID : 19172433
• Iijima K, Koike T, Sekine H, Abe Y, Asanuma K, Ara N, Uno K, Imatani A, Ohara S, Shimosegawa TSustained epithelial proliferation in a functionally irreversible fundic mucosa after Helicobacter pylori eradication.J Gastroenterol ( 2009) 44(1): 47-55PMID : 19159072
• Iijima K, Ichikawa T, Okada S, Ogawa M, Koike T, Ohara S, Shimosegawa TRebamipide, a cytoprotective drug, increases gastric mucus secretion in human: evaluations with endoscopic gastrin test.Dig Dis Sci ( 2009) 54(7): 1500-7PMID : 18975081

2008年(10件)

• Strober W, Kitani A, Fuss I, Asano N, Watanabe TThe molecular basis of NOD2 susceptibility mutations in Crohn's disease.Mucosal Immunol ( 2008) 1 Suppl 1 S5-9PMID : 19079230
• Yamagishi H, Koike T, Ohara S, Kobayashi S, Ariizumi K, Abe Y, Iijima K, Imatani A, Inomata Y, Kato K, Shibuya D, Aida S, Shimosegawa TTongue-like Barrett's esophagus is associated with gastroesophageal reflux disease.World J Gastroenterol ( 2008) 14(26): 4196-203PMID : 18636666
• Ariizumi K, Koike T, Ohara S, Inomata Y, Abe Y, Iijima K, Imatani A, Oka T, Shimosegawa TIncidence of reflux esophagitis and H pylori infection in diabetic patients.World J Gastroenterol ( 2008) 14(20): 3212-7PMID : 18506928
• Yamagishi H, Koike T, Ohara S, Horii T, Kikuchi R, Kobayashi S, Abe Y, Iijima K, Imatani A, Suzuki K, Hishinuma T, Goto J, Shimosegawa TStronger inhibition of gastric acid secretion by lafutidine, a novel H2 receptor antagonist, than by the proton pump inhibitor lansoprazole.World J Gastroenterol ( 2008) 14(15): 2406-10PMID : 18416470
• Yamagishi H, Koike T, Ohara S, Horii T, Kikuchi R, Kobayashi S, Abe Y, Iijima K, Imatani A, Suzuki K, Hishinuma T, Goto J, Shimosegawa TEarly effects of Lansoprazole orally disintegrating tablets on intragastric pH in CYP2C19 extensive metabolizers.World J Gastroenterol ( 2008) 14(13): 2049-54PMID : 18395905
• Yamagishi H, Koike T, Ohara S, Kobayashi S, Ariizumi K, Abe Y, Iijima K, Imatani A, Inomata Y, Kato K, Shibuya D, Aida S, Shimosegawa TPrevalence of gastroesophageal reflux symptoms in a large unselected general population in Japan.World J Gastroenterol ( 2008) 14(9): 1358-64PMID : 18322948
• Asano N, Watanabe T, Kitani A, Fuss IJ, Strober WNotch1 signaling and regulatory T cell function.J Immunol ( 2008) 180(5): 2796-804PMID : 18292500
• Terai S, Iijima K, Kato K, Dairaku N, Suzuki T, Yoshida M, Koike T, Kitagawa Y, Imatani A, Sekine H, Ohara S, Shimosegawa TLong-term outcomes of gastric mucosa-associated lymphoid tissue lymphomas after Helicobacter pylori eradication therapy.Tohoku J Exp Med ( 2008) 214(1): 79-87PMID : 18212490
• Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, Kitani A, Strober WMuramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.J Clin Invest ( 2008) 118(2): 545-59PMID : 18188453
• Ara N, Iijima K, Asanuma K, Yoshitake J, Ohara S, Shimosegawa T, Yoshimura TDisruption of gastric barrier function by luminal nitrosative stress: a potential chemical insult to the human gastro-oesophageal junction.Gut ( 2008) 57(3): 306-13PMID : 17965057

下部消化管グループ

2026年(2件)

• Kakuta Y, Li D, Debbas P, Okazaki S, Sawahashi M, Yang S, Iwaki H, Okamoto D, Nagai H, Shimoyama Y, Naito T, Moroi R, Kuroha M, Shiga H, Kinouchi Y, Shirai T, Fujii H, McGovern DPB, Masamune ADifferences in Anti-αvβ6 Integrin Antibody Expression between U.S. and Japanese Cohorts in Inflammatory Bowel Disease.Inflamm Bowel Dis ( 2026) 32(1): 130-140PMID : 41274279
• Kyo R, Sasaki T, Yoshida S, Isayama H, Yamada T, Enomoto T, Sumida Y, Kuwai T, Tomita M, Matsuzawa T, Moroi R, Shiratori T, Saida YLong-term results of palliative placement of very low-axial force self-expandable metallic stents for malignant colorectal obstruction.DEN Open ( 2026) 6(1): e70126PMID : 40322541

2025年(9件)

• Yoshida A, Takagi T, Kawashima K, Moriya K, Bamba S, Sagami S, Hayashi T, Kaneko M, Naito T, Kanmura S, Asaeda K, Ishihara S, Nagamatsu S, Endo Y, Ueno F, Morizane T, Matsuoka K, Hibi TPredictive factors for primary nonresponse to biologics in ulcerative colitis: a prospective multicenter study.J Gastroenterol ( 2025) PMID : 41201536
• Wagatsuma K, Nojima M, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Takeuchi K, Tamura S, Kinjo F, Ueno N, Naganuma M, Watanabe K, Moroi R, Nishimata N, Motoya S, Kurahara K, Takahashi S, Maemoto A, Hiraga H, Saruta M, Tominaga K, Hisabe T, Tanaka H, Terai S, Inokuchi T, Takedomi H, Narimatsu K, Endo K, Nakamura M, Hisamatsu T, Nakase HPost Hoc Analysis of Anxiety and Behavioral Changes in Japanese Patients With Inflammatory Bowel Disease due to the COVID-19 Pandemic: Relationship Between Municipal Population at the Place of Residence and Anxiety.JGH Open ( 2025) 9(7): e70209PMID : 40666190
• Sasaki A, Kuroha M, Tosa M, Takahashi S, Oomori S, Nomura E, Kikuchi T, Onodera M, Sato Y, Miyazawa T, Chiba H, Yokoyama N, Kusaka J, Okamoto D, Handa T, Sugimura M, Iwabuchi M, Hiramoto K, Shirota H, Iwaki H, Nagai H, Shimoyama Y, Naito T, Moroi R, Shiga H, Kakuta Y, Kinouchi Y, Masamune AEvaluation of Organoid-Derived Exosomal microRNA as Liquid Biopsy for Colorectal Cancer: A Multicenter Cross-Sectional Study.Clin Transl Sci ( 2025) 18(6): e70270PMID : 40516061
• Urushiyama M, Tarasawa K, Moroi R, Iwaki H, Hoshi Y, Nagai H, Shimoyama Y, Naito T, Kakuta F, Shiga H, Hamada S, Kakuta Y, Fushimi K, Kinouchi Y, Abukawa D, Fujimori K, Masamune AEvolving Trends in Pediatric Inflammatory Bowel Disease Management in Japan: A Decade of Nationwide Data.JGH Open ( 2025) 9(5): e70175PMID : 40375856
• Sawahashi M, Kakuta Y, Naito T, Okazaki S, Ohneda K, Orui M, Obara T, Ogishima S, Kumada K, Kudo H, Nagami F, Hozawa A, Iwaki H, Nagai H, Shimoyama Y, Moroi R, Shiga H, Kinouchi Y, Shirai T, Fujii H, Masamune AAutoantibodies against endothelial protein C receptor and integrin αvβ6 predict the development of ulcerative colitis.J Gastroenterol ( 2025) 60(9): 1108-1117PMID : 40372451
• Moroi R, Nochioka K, Miyata S, Iwaki H, Chiba H, Nagai H, Shimoyama Y, Naito T, Shiga H, Tosa M, Kakuta Y, Kayaba S, Takahashi S, Kinouchi Y, Masamune AEndoscopic radial incision and cutting using balloon-assisted enteroscopy for small intestinal stenosis related to Crohn's disease: a pilot study.Intest Res ( 2025) 23(3): 302-308PMID : 39832776
• Nochioka K, Yasuda S, Shiroto T, Yamamoto S, Sato H, Hasebe Y, Godo S, Nakano M, Shindo T, Nishimiya K, Hao K, Takahashi J, Ido K, Kakuta Y, Shimizu H, Shimokawa H, Nakayama MThe outcomes of electronic personal health records in patients with heart failure or coronary artery disease.ESC Heart Fail ( 2025) 12(2): 1464-1468PMID : 39543917
• Moroi R, Nochioka K, Miyata S, Iwaki H, Chiba H, Nagai H, Shimoyama Y, Naito T, Shiga H, Tosa M, Kakuta Y, Kayaba S, Takahashi S, Kinouchi Y, Masamune ASafety and effectiveness of additional triamcinolone acetonide with endoscopic radial incision and cutting for benign stenosis of the lower gastrointestinal tract: A pilot study.DEN Open ( 2025) 5(1): e70002PMID : 39228860
• Oyama H, Moroi R, Sakuma A, Shimoyama Y, Nagai H, Naito T, Shiga H, Kakuta Y, Kinouchi Y, Masamune AChronic Poor Sleep is Associated with Increased Disease Activity in Patients with Ulcerative Colitis: Prospective Observational Study in Japan.J Crohns Colitis ( 2025) 19(1):PMID : 39052880

2024年(18件)

• Moroi R, Tarasawa K, Nagai H, Shimoyama Y, Naito T, Shiga H, Hamada S, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AClinical Practice and Safety of Endoscopic Balloon Dilation for Crohn's Disease-Related Strictures: A Nationwide Claim Database Analysis in Japan.Gastroenterol Res Pract ( 2024) 2024 1291965PMID : 39574969
• Sawahashi M, Moroi R, Kakuta Y, Nagai H, Shimoyama Y, Naito T, Shiga H, Masamune ADifferences in Clinical Practice and Disease Course Between Elderly-Onset and Long-Standing Elderly Ulcerative Colitis: A Single-Center Study in Japan.Tohoku J Exp Med ( 2024) 264(3): 109-116PMID : 38987210
• Naito T, Osaka R, Kakuta Y, Kawai Y, Khor SS, Umeno J, Tokunaga K, Nagai H, Shimoyama Y, Moroi R, Shiga H, Nagasaki M, Kinouchi Y, Masamune AGenetically Predicted Higher Levels of Caffeic Acid Are Protective Against Ulcerative Colitis: A Comprehensive Metabolome Analysis.Inflamm Bowel Dis ( 2024) 30(12): 2440-2448PMID : 38944808
• Korekawa K, Shimoyama Y, Fujishima F, Nagai H, Naito T, Moroi R, Shiga H, Kakuta Y, Kinouchi Y, Masamune AWhite spots around colorectal tumors are cancer-related findings and may aid endoscopic diagnosis: a prospective study in Japan.Clin Endosc ( 2024) 57(5): 637-646PMID : 38902852
• Moroi R, Kakuta Y, Nagai H, Shimoyama Y, Naito T, Shiga H, Kinouchi Y, Masamune AClinical practice and outcome of patients with elderly-onset ulcerative colitis: Insights from a nationwide claims database study in Japan.JGH Open ( 2024) 8(6): e13103PMID : 38887512
• Moroi R, Hishinuma K, Sugawara Y, Nochioka K, Shimoyama Y, Naito T, Shiga H, Kakuta Y, Kinouchi Y, Tsuji I, Masamune AThe Efficacy of Combination Therapy with Ustekinumab and Budesonide for Crohn's Disease: A Randomized Controlled Trial.Inflamm Intest Dis ( 2024) 9(1): 40-46PMID : 38860189
• Ghosh S, Feagan BG, Parra RS, Lopes S, Steinlauf A, Kakuta Y, Joshi N, Lee WJ, Lacerda AP, Zhou Q, Xuan S, Kligys K, Shukla N, Louis EImpact of Upadacitinib Induction and Maintenance Therapy on Health-related Quality of Life, Fatigue, and Work Productivity in Patients with Moderately-to-severely Active Crohn's Disease.J Crohns Colitis ( 2024) 18(11): 1804-1818PMID : 38835235
• Makuuchi M, Kakuta Y, Umeno J, Fujii T, Takagawa T, Ibuka T, Miura M, Sasaki Y, Takahashi S, Nakase H, Kiyohara H, Tominaga K, Shimodaira Y, Hiraoka S, Ueno N, Yanai S, Yoshihara T, Kakimoto K, Matsuoka K, Hayashi R, Nanjo S, Iwama I, Ishiguro Y, Chiba H, Endo K, Kagaya T, Fukuda T, Sakata Y, Kudo T, Takagi T, Takahashi K, Naganuma M, Shinozaki M, Ogata N, Tanaka H, Narimatsu K, Miyazaki H, Ishige T, Onodera M, Hashimoto Y, Nagai H, Shimoyama Y, Naito T, Moroi R, Shiga H, Kinouchi Y, Andoh A, Hisamatsu T, Masamune AReal-world NUDT15 genotyping and thiopurine treatment optimization in inflammatory bowel disease: a multicenter study.J Gastroenterol ( 2024) 59(6): 468-482PMID : 38589597
• Takahashi S, Kakuta Y, Obara T, Ishikawa T, Nagai H, Shimoyama Y, Naito T, Moroi R, Shiga H, Mano N, Kinouchi Y, Masamune APrescribing in pregnant women with inflammatory bowel disease and its relationship to congenital malformations in Japan.J Gastroenterol Hepatol ( 2024) 39(7): 1291-1298PMID : 38538533
• Shiga H, Nagai H, Shimoyama Y, Naito T, Moroi R, Kakuta Y, Kinouchi Y, Masamune ALive-attenuated vaccination in patients with inflammatory bowel disease while continuing or after elective switch to vedolizumab.Intest Res ( 2024) 22(3): 378-386PMID : 38523452
• Moroi R, Shiga H, Nochioka K, Chiba H, Shimoyama Y, Onodera M, Naito T, Tosa M, Kakuta Y, Sato Y, Kayaba S, Takahashi S, Miyata S, Kinouchi Y, Masamune AA Phase II Clinical Trial to Study the Safety of Triamcinolone after Endoscopic Radial Incision and Cutting Dilatation for Benign Stenosis of the Lower Gastrointestinal Tract: A Study Protocol.Kurume Med J ( 2024) 70(1.2): 53-60PMID : 38508736
• Khrom M, Long M, Dube S, Robbins L, Botwin GJ, Yang S, Mengesha E, Li D, Naito T, Bonthala NN, Ha C, Melmed G, Rabizadeh S, Syal G, Vasiliauskas E, Ziring D, Brant SR, Cho J, Duerr RH, Rioux J, Schumm P, Silverberg M, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Xavier RJ, Kugathasan S, Hercules D, Targan SR, Sartor RB, Haritunians T, McGovern DPBComprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease.Gastroenterology ( 2024) 167(2): 315-332PMID : 38490347
• Moroi R, Kakuta Y, Nagai H, Shimoyama Y, Naito T, Shiga H, Kinouchi Y, Masamune AClinical Utilization of Generic Drugs and Biosimilars for Ulcerative Colitis Treatment: Insights from a Nationwide Database Study in Japan.Inflamm Intest Dis ( 2024) 9(1): 29-39PMID : 38344420
• Inomata Y, Kuroha M, Shimoyama Y, Naito T, Moroi R, Shiga H, Kakuta Y, Karasawa H, Onuma S, Kinouchi Y, Masamune ADickkopf 1 is expressed in normal fibroblasts during early stages of colorectal tumorigenesis.Cancer Med ( 2024) 13(2): e6992PMID : 38334454
• Yokota Y, Imai T, Kawahara M, Inatomi O, Nishida A, Kakuta Y, Masamune A, Andoh AThiopurines exert harmful effects on spermatogenesis in Nudt15(R138C) knock-in mice.J Gastroenterol ( 2024) 59(2): 109-118PMID : 38097780
• Moroi R, Tarasawa K, Nagai H, Shimoyama Y, Naito T, Shiga H, Hamada S, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AEffectiveness of Antibiotics for Uncomplicated Diverticulitis: A Retrospective Investigation Using a Nationwide Database in Japan.Digestion ( 2024) 105(2): 81-89PMID : 37857266
• Takahashi T, Shiga H, Tarasawa K, Shimoyama Y, Naito T, Moroi R, Kuroha M, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AComparative Effectiveness of Tacrolimus and Infliximab in Hospitalized Patients With Ulcerative Colitis.Clin Transl Gastroenterol ( 2024) 15(1): e00642PMID : 37753937
• Inomata Y, Naito T, Hiratsuka T, Shimoyama Y, Moroi R, Shiga H, Kakuta Y, Kayada K, Ohara Y, Asano N, Aoki S, Unno M, Masamune ARupture of ectopic varices of the ascending colon occurring after pancreatic cancer surgery: A case report and literature review.DEN Open ( 2024) 4(1): e255PMID : 37441155

2023年(18件)

• Moroi R, Kakuta Y, Obara T, Shimoyama Y, Naito T, Shiga H, Kinouchi Y, Masamune ALong-term prognosis and clinical practice for new-onset ulcerative colitis in the era of biologics: A Japanese retrospective study.JGH Open ( 2023) 7(10): 682-689PMID : 37908295
• Naganuma M, Kobayashi T, Kunisaki R, Matsuoka K, Yamamoto S, Kawamoto A, Saito D, Nanki K, Narimatsu K, Shiga H, Esaki M, Yoshioka S, Kato S, Saruta M, Tanaka S, Yasutomi E, Yokoyama K, Moriya K, Tsuzuki Y, Ooi M, Fujiya M, Nakazawa A, Abe T, Hisamatsu TReal-world efficacy and safety of advanced therapies in hospitalized patients with ulcerative colitis.J Gastroenterol ( 2023) 58(12): 1198-1210PMID : 37831183
• Kakuta Y, Kato M, Shimoyama Y, Naito T, Moroi R, Kuroha M, Shiga H, Kinouchi Y, Masamune AUsefulness and difficulties with the thiopurine pharmacogenomic NUDT15 genotyping test: Analysis of real-world data in Japan.J Pharmacol Sci ( 2023) 153(3): 161-169PMID : 37770157
• Korekawa K, Naito T, Fujishima F, Nagai H, Shimoyama Y, Moroi R, Shiga H, Kakuta Y, Masamune ASmall bowel cancer in a patient with Crohn's disease diagnosed preoperatively by double-balloon enteroscopy.Clin J Gastroenterol ( 2023) 16(6): 836-841PMID : 37597132
• Shimoda F, Naito T, Kakuta Y, Kawai Y, Tokunaga K, Shimoyama Y, Moroi R, Shiga H, Nagasaki M, Kinouchi Y, Masamune AHLA-DQA1*05 and upstream variants of PPARGC1B are associated with infliximab persistence in Japanese Crohn's disease patients.Pharmacogenomics J ( 2023) 23(6): 141-148PMID : 37460671
• Kakuta Y, Kinouchi Y, Masamune AGenetics of inflammatory bowel disease in East Asia: From population to individual.J Gastroenterol Hepatol ( 2023) 38(7): 1116-1122PMID : 37278363
• Hirai M, Yanai S, Kunisaki R, Nishio M, Watanabe K, Sato T, Ishihara S, Anzai H, Hisabe T, Yasukawa S, Maeda Y, Takishima K, Ohno A, Shiga H, Uraoka T, Itoi Y, Ogata H, Takabayashi K, Yoshida N, Saito Y, Takamaru H, Kawasaki K, Esaki M, Tsuruoka N, Hisamatsu T, Matsumoto TEffectiveness of endoscopic resection for colorectal neoplasms in ulcerative colitis: a multicenter registration study.Gastrointest Endosc ( 2023) 98(5): 806-812PMID : 37263363
• Khrom M, Li D, Naito T, Lee HS, Botwin GJ, Potdar AA, Boucher G, Yang S, Mengesha E, Dube S, Song K, McGovern DPB, Haritunians TSex-Dimorphic Analyses Identify Novel and Sex-Specific Genetic Associations in Inflammatory Bowel Disease.Inflamm Bowel Dis ( 2023) 29(10): 1622-1632PMID : 37262302
• Liu Z, Liu R, Gao H, Jung S, Gao X, Sun R, Liu X, Kim Y, Lee HS, Kawai Y, Nagasaki M, Umeno J, Tokunaga K, Kinouchi Y, Masamune A, Shi W, Shen C, Guo Z, Yuan K, Zhu S, Li D, Liu J, Ge T, Cho J, Daly MJ, McGovern DPB, Ye BD, Song K, Kakuta Y, Li M, Huang HGenetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.Nat Genet ( 2023) 55(5): 796-806PMID : 37156999
• Moroi R, Yano K, Tarasawa K, Shimoyama Y, Naito T, Shiga H, Hamada S, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AThe Impact of Concomitant Ulcerative Colitis on the Clinical Course in Patients with Primary Sclerosing Cholangitis: An Investigation Using a Nationwide Database in Japan.Inflamm Intest Dis ( 2023) 7(3-4): 147-154PMID : 37064536
• Yamamoto T, Nakase H, Watanabe K, Shinzaki S, Takatsu N, Fujii T, Okamoto R, Matsuoka K, Yamada A, Kunisaki R, Matsuura M, Shiga H, Bamba S, Mikami Y, Shimoyama T, Motoya S, Torisu T, Kobayashi T, Ohmiya N, Saruta M, Matsuda K, Matsumoto T, Maemoto A, Murata Y, Yoshigoe S, Nagasaka S, Yajima T, Hisamatsu TDiagnosis and Clinical Features of Perianal Lesions in Newly Diagnosed Crohn's Disease: Subgroup Analysis from Inception Cohort Registry Study of Patients with Crohn's Disease (iCREST-CD).J Crohns Colitis ( 2023) 17(8): 1193-1206PMID : 36869815
• Terui H, Moroi R, Masamune A, Aiba S, Yamasaki KPossible Efficacy of Vedolizumab, an Anti-α4β7 Integrin Antibody, in Palmoplantar Pustulosis.Case Rep Dermatol ( 2023) 15(1): 22-25PMID : 36726801
• Moroi R, Tarasawa K, Ikeda M, Matsumoto R, Shimoyama Y, Naito T, Takikawa T, Shiga H, Hamada S, Kakuta Y, Kikuta K, Fushimi K, Fujimori K, Kinouchi Y, Masamune ASeverity of acute pancreatitis in patients with inflammatory bowel disease in the era of biologics: A propensity-score-matched analysis using a nationwide database in Japan.JGH Open ( 2023) 7(1): 40-47PMID : 36660049
• Nakase H, Wagatsuma K, Nojima M, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Takeuchi K, Tamura S, Kinjo F, Ueno N, Naganuma M, Watanabe K, Moroi R, Nishimata N, Motoya S, Kurahara K, Takahashi S, Maemoto A, Sakuraba H, Saruta M, Tominaga K, Hisabe T, Tanaka H, Terai S, Hiraoka S, Takedomi H, Narimatsu K, Endo K, Nakamura M, Hisamatsu TAnxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national survey.J Gastroenterol ( 2023) 58(3): 205-216PMID : 36607399
• Kakuta Y, Naito T, Kinouchi Y, Masamune ACurrent Status and Future Prospects of Inflammatory Bowel Disease Genetics.Digestion ( 2023) 104(1): 7-15PMID : 36323245
• Shiga H, Takahashi T, Shiraki M, Kojima Y, Tsuji T, Takagi S, Hiramoto K, Yokoyama N, Sugimura M, Iwabuchi M, Endo K, Onodera M, Sato Y, Shimodaira Y, Nomura E, Kikuchi T, Chiba H, Oomori S, Kudo H, Kumada K, Nagaie S, Ogishima S, Nagami F, Shimoyama Y, Moroi R, Kuroha M, Kakuta Y, Ishige T, Kinouchi Y, Masamune AReduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents.Scand J Gastroenterol ( 2023) 58(4): 360-367PMID : 36222610
• Shiga H, Kakuta Y, An K, Abe Y, Fujimaki S, Shimoyama Y, Naito T, Moroi R, Kuroha M, Khor SS, Kawai Y, Tokunaga K, Kinouchi Y, Masamune AResponse to COVID-19 vaccine is reduced in patients with inflammatory bowel disease, but improved with additional dose.J Gastroenterol Hepatol ( 2023) 38(1): 44-51PMID : 36066279
• Kakuta Y, Shirai T, McGovern DPB, Braun J, Fujii H, Masamune ANovel Diagnostic Autoantibodies Against Endothelial Protein C Receptor in Patients With Ulcerative Colitis.Clin Gastroenterol Hepatol ( 2023) 21(3): 844-846PMID : 34971808

2022年(15件)

• Oyama H, Moroi R, Tarasawa K, Shimoyama Y, Naito T, Sakuma A, Shiga H, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune ADepression is associated with increased disease activity in patients with ulcerative colitis: A propensity score-matched analysis using a nationwide database in Japan.JGH Open ( 2022) 6(12): 876-885PMID : 36514494
• Shiga H, Tarasawa K, Moroi R, Makuuchi M, Takahashi T, Shimoyama Y, Kuroha M, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune ALong-term effectiveness of ustekinumab comparable to antitumor necrosis factor agents in patients with Crohn's disease.J Gastroenterol Hepatol ( 2022) 37(11): 2105-2112PMID : 36059265
• Takahashi S, Obara T, Kakuta Y, Shimoyama Y, Naito T, Moroi R, Kuroha M, Shiga H, Kinouchi Y, Masamune AValidity of Diagnostic Algorithms for Inflammatory Bowel Disease in Japanese Hospital Claims Data.Int J Environ Res Public Health ( 2022) 19(13):PMID : 35805591
• Akaishi T, Takahashi T, Sato S, Jin X, Masamune A, Ishii TProlonged Diarrhea Following COVID-19 Vaccination: A Case Report and Literature Review.Tohoku J Exp Med ( 2022) 257(3): 251-259PMID : 35644543
• Abe I, Shiga H, Chiba H, Miyazawa T, Oomori S, Shimoyama Y, Moroi R, Kuroha M, Kakuta Y, Kinouchi Y, Masamune ASerum leucine-rich alpha-2 glycoprotein as a predictive factor of endoscopic remission in Crohn's disease.J Gastroenterol Hepatol ( 2022) 37(9): 1741-1748PMID : 35641439
• Ohneda K, Hiratsuka M, Kawame H, Nagami F, Suzuki Y, Suzuki K, Uruno A, Sakurai-Yageta M, Hamanaka Y, Taira M, Ogishima S, Kuriyama S, Hozawa A, Tomita H, Minegishi N, Sugawara J, Danjoh I, Nakamura T, Kobayashi T, Yamaguchi-Kabata Y, Tadaka S, Obara T, Hishimuma E, Mano N, Matsuura M, Sato Y, Nakasone M, Honkura Y, Suzuki J, Katori Y, Kakuta Y, Masamune A, Aoki Y, Nakayama M, Kure S, Kinoshita K, Fuse N, Yamamoto MA Pilot Study for Return of Individual Pharmacogenomic Results to Population-Based Cohort Study Participants.JMA J ( 2022) 5(2): 177-189PMID : 35611229
• Moroi R, Shiga H, Nochioka K, Chiba H, Shimoyama Y, Kuroha M, Tosa M, Kakuta Y, Kayaba S, Takahashi S, Kinouchi Y, Masamune AEndoscopic radial incision and cutting for benign stenosis of the lower gastrointestinal tract: An investigation of novel endoscopic treatment in multicenter trial.J Gastroenterol Hepatol ( 2022) 37(8): 1554-1560PMID : 35506307
• Moroi R, Shiga H, Nochioka K, Shimoyama Y, Kuroha M, Kakuta Y, Kinouchi Y, Masamune AA pilot study investigating the safety and feasibility of endoscopic dilation using a radial incision and cutting technique for benign strictures of the small intestine: a study protocol.Pilot Feasibility Stud ( 2022) 8(1): 85PMID : 35440064
• Moroi R, Tarasawa K, Shimoyama Y, Kuroha M, Shiga H, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AEffectiveness of colonic stent placement for obstructive colorectal cancers: An analysis of short-term results using a nationwide database in Japan.J Gastroenterol Hepatol ( 2022) 37(7): 1316-1325PMID : 35434862
• Ishii K, Shirai T, Kakuta Y, Machiyama T, Sato H, Ishii T, Harigae H, Fujii HDevelopment of severe colitis in Takayasu arteritis treated with tocilizumab.Clin Rheumatol ( 2022) 41(6): 1911-1918PMID : 35188603
• Yano K, Moroi R, Shiga H, Tarasawa K, Shimoyama Y, Kuroha M, Hamada S, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AAnalysis of the disease activity of ulcerative colitis with and without concomitant primary sclerosing cholangitis: An investigation using a nationwide database in Japan.JGH Open ( 2022) 6(1): 50-56PMID : 35071788
• Kakuta Y, Iwaki H, Umeno J, Kawai Y, Kawahara M, Takagawa T, Shimoyama Y, Naito T, Moroi R, Kuroha M, Shiga H, Watanabe K, Nakamura S, Nakase H, Sasaki M, Hanai H, Fuyuno Y, Hirano A, Matsumoto T, Kudo H, Minegishi N, Nakamura M, Hisamatsu T, Andoh A, Nagasaki M, Tokunaga K, Kinouchi Y, Masamune ACrohn's Disease and Early Exposure to Thiopurines are Independent Risk Factors for Mosaic Chromosomal Alterations in Patients with Inflammatory Bowel Diseases.J Crohns Colitis ( 2022) 16(4): 643-655PMID : 34751398
• Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, Andoh A, Hiraoka S, Shinozaki M, Fujii T, Katsurada T, Kobayashi T, Fujiya M, Otsuka T, Oshima N, Suzuki Y, Sato Y, Hokari R, Noguchi M, Ohta Y, Matsuura M, Kawai Y, Tokunaga K, Nagasaki M, Kudo H, Minegishi N, Okamoto D, Shimoyama Y, Moroi R, Kuroha M, Shiga H, Li D, McGovern DPB, Kinouchi Y, Masamune AGenetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease.Inflamm Bowel Dis ( 2022) 28(1): 21-31PMID : 33501934
• Shiga H, Abe I, Kusaka J, Shimoyama Y, Moroi R, Kuroha M, Kakuta Y, Kinouchi Y, Masamune ACapsule Endoscopy Is Useful for Postoperative Tight Control Management in Patients with Crohn's Disease.Dig Dis Sci ( 2022) 67(1): 263-272PMID : 33495918
• Maeda T, Sakuraba H, Hiraga H, Yoshida S, Kakuta Y, Kikuchi H, Kawaguchi S, Hasui K, Tatsuta T, Chinda D, Mikami T, Fukuda SLong-term efficacy and tolerability of dose-adjusted thiopurine treatment in maintaining remission in inflammatory bowel disease patients with NUDT15 heterozygosity.Intest Res ( 2022) 20(1): 90-100PMID : 33472343

2021年(17件)

• Hishinuma K, Moroi R, Okamoto D, Shimoyama Y, Kuroha M, Shiga H, Kakuta Y, Kinouchi Y, Masamune AAnalysis of the Long-Term Prognosis in Japanese Patients with Ulcerative Colitis Treated with New Therapeutic Agents and the Correlation between Prognosis and Disease Susceptibility Loci.Inflamm Intest Dis ( 2021) 6(3): 154-164PMID : 34722645
• Ando K, Fujiya M, Watanabe K, Hiraoka S, Shiga H, Tanaka S, Iijima H, Mizushima T, Kobayashi T, Nagahori M, Ikeuchi H, Kato S, Torisu T, Kobayashi K, Higashiyama M, Fukui T, Kagaya T, Esaki M, Yanai S, Abukawa D, Naganuma M, Motoya S, Saruta M, Bamba S, Sasaki M, Uchiyama K, Fukuda K, Suzuki H, Nakase H, Shimizu T, Iizuka M, Watanabe M, Suzuki Y, Hisamatsu TA nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan.J Gastroenterol ( 2021) 56(12): 1062-1079PMID : 34611740
• Masu Y, Kanazawa Y, Kakuta Y, Shimoyama Y, Onodera M, Naito T, Moroi R, Kuroha M, Kimura T, Shiga H, Kinouchi Y, Masamune AImmunoglobulin subtype-coated bacteria are correlated with the disease activity of inflammatory bowel disease.Sci Rep ( 2021) 11(1): 16672PMID : 34404881
• Moroi R, Shiga H, Tarasawa K, Yano K, Shimoyama Y, Kuroha M, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AThe clinical practice of ulcerative colitis in elderly patients: An investigation using a nationwide database in Japan.JGH Open ( 2021) 5(8): 842-848PMID : 34386590
• Shimoda F, Kuroha M, Chiba H, Abe I, Yano K, Inomata Y, Takahashi T, Shimoyama Y, Moroi R, Shiga H, Kakuta Y, Fujishima F, Masamune AUlcerative colitis-related postoperative enteritis treated with anti-tumor necrosis factor therapy: two case reports and a literature review.Clin J Gastroenterol ( 2021) 14(5): 1396-1403PMID : 34302278
• Andoh A, Kawahara M, Imai T, Tatsumi G, Inatomi O, Kakuta YThiopurine pharmacogenomics and pregnancy in inflammatory bowel disease.J Gastroenterol ( 2021) 56(10): 881-890PMID : 34287682
• Handa T, Kuroha M, Nagai H, Shimoyama Y, Naito T, Moroi R, Kanazawa Y, Shiga H, Kakuta Y, Kinouchi Y, Masamune ALiquid Biopsy for Colorectal Adenoma: Is the Exosomal miRNA Derived From Organoid a Potential Diagnostic Biomarker?Clin Transl Gastroenterol ( 2021) 12(5): e00356PMID : 33979310
• Kuroha M, Yoshinaga T, Yazaki M, Fujishima F, Handa T, Suzuki K, Hishinuma K, Masu Y, Shimoyama Y, Naito T, Moroi R, Kanazawa Y, Shiga H, Kakuta Y, Masamune ALocalized intestinal AL amyloidosis detected as bright green using autofluorescence endoscopy.Clin J Gastroenterol ( 2021) 14(3): 815-819PMID : 33904108
• Inomata Y, Kuroha M, Handa T, Shimoyama Y, Moroi R, Shiga H, Kakuta Y, Ichikawa S, Fukuhara N, Sato Y, Takahashi T, Masamune ALong-term endoscopic remission in Crohn's disease after allogeneic hematopoietic stem cell transplantation for diffuse large B cell lymphoma: case report and literature review.Clin J Gastroenterol ( 2021) 14(4): 1108-1114PMID : 33786703
• Shirai T, Kakuta Y, Fujii HDistinct Autoantibodies Against Endothelial Protein C Receptor in Ulcerative Colitis.Gastroenterology ( 2021) 161(5): 1724-1725PMID : 33773994
• Imai T, Kawahara M, Tatsumi G, Yamashita N, Nishishita-Asai A, Inatomi O, Masamune A, Kakuta Y, Andoh AThiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15^R138C Knock-In Mice.Cell Mol Gastroenterol Hepatol ( 2021) 12(1): 335-337PMID : 33766784
• Nagai H, Kuroha M, Handa T, Karasawa H, Ohnuma S, Naito T, Moroi R, Kanazawa Y, Shiga H, Hamada S, Kakuta Y, Naitoh T, Kinouchi Y, Shimosegawa T, Masamune AComprehensive Analysis of microRNA Profiles in Organoids Derived from Human Colorectal Adenoma and Cancer.Digestion ( 2021) 102(6): 860-869PMID : 33647915
• Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPBAltered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease.Gastroenterology ( 2021) 160(3): 809-822.e7PMID : 33160965
• Moroi R, Tarasawa K, Shiga H, Yano K, Shimoyama Y, Kuroha M, Kakuta Y, Fushimi K, Fujimori K, Kinouchi Y, Masamune AEfficacy of urgent colonoscopy for colonic diverticular bleeding: A propensity score-matched analysis using a nationwide database in Japan.J Gastroenterol Hepatol ( 2021) 36(6): 1598-1604PMID : 33119929
• Naito T, Botwin GJ, Haritunians T, Li D, Yang S, Khrom M, Braun J, Abbou L, Mengesha E, Stevens C, Masamune A, Daly M, McGovern DPBPrevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease.Gastroenterology ( 2021) 160(3): 771-780.e4PMID : 33098885
• Kuroha M, Shiga H, Kanazawa Y, Nagai H, Handa T, Ichikawa R, Onodera M, Naito T, Moroi R, Kimura T, Endo K, Kakuta Y, Kinouchi Y, Shimosegawa T, Masamune AFactors Associated with Fibrosis during Colorectal Endoscopic Submucosal Dissection: Does Pretreatment Biopsy Potentially Elicit Submucosal Fibrosis and Affect Endoscopic Submucosal Dissection Outcomes?Digestion ( 2021) 102(4): 590-598PMID : 32866955
• Shiga H, Abe I, Masamune AMethotrexate-associated Lymphoproliferative Disorder of the Small Intestine.Clin Gastroenterol Hepatol ( 2021) 19(6): e62-e63PMID : 32205225

2020年(13件)

• Endo K, Kakuta Y, Moroi R, Yamamoto K, Shiga H, Kuroha M, Naito T, Kinouchi Y, Masamune A<i>TL1A</i> (<i>TNFSF15</i>) genotype affects the long-term therapeutic outcomes of anti-TNFα antibodies for Crohn's disease patients.JGH Open ( 2020) 4(6): 1108-1113PMID : 33319044
• Kakuta Y, Nakano T, Naito T, Watanabe K, Izumiyama Y, Okamoto D, Ichikawa R, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Naitoh T, Kinouchi Y, Unno M, Masamune ARepertoire analysis of memory T-cell receptors in Japanese patients with inflammatory bowel disease.JGH Open ( 2020) 4(4): 624-631PMID : 32782948
• Kakuta Y, Ichikawa R, Fuyuno Y, Hirano A, Umeno J, Torisu T, Watanabe K, Asakura A, Nakano T, Izumiyama Y, Okamoto D, Naito T, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Naito T, Esaki M, Kawai Y, Tokunaga K, Nakamura M, Matsumoto T, Nagasaki M, Kinouchi Y, Unno M, Masamune AAn Integrated Genomic and Transcriptomic Analysis Reveals Candidates of Susceptibility Genes for Crohn's Disease in Japanese Populations.Sci Rep ( 2020) 10(1): 10236PMID : 32581322
• Tomiyoshi K, Sato H, Tominaga K, Kawata Y, Okamoto D, Kakuta Y, Yokoyama J, Terai SRare Genotype of His/His in NUDT15 Codon 139 and Thiopurine-associated Adverse Events in a Case of Ulcerative Colitis.Intern Med ( 2020) 59(13): 1611-1613PMID : 32269192
• Moroi R, Shiga H, Endo K, Yamamoto K, Kuroha M, Kanazawa Y, Kakuta Y, Kinouchi Y, Masamune ALong-Term Prognosis of Japanese Patients with Crohn's Disease Treated by Switching Anti-Tumor Necrosis Factor-α Antibodies.Inflamm Intest Dis ( 2020) 5(1): 11-19PMID : 32232050
• Kakuta Y, Kinouchi Y, Masamune A[Pretreatment screening for inflammatory bowel diseases;significance and problems in genotyping of NUDT15].Nihon Shokakibyo Gakkai Zasshi ( 2020) 117(3): 195-207PMID : 32161240
• Mutoh T, Shirai T, Ishii T, Shirota Y, Fujishima F, Takahashi F, Kakuta Y, Kanazawa Y, Masamune A, Saiki Y, Harigae H, Fujii HIdentification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.Nat Commun ( 2020) 11(1): 1253PMID : 32152303
• Okamoto D, Kawai Y, Kakuta Y, Naito T, Torisu T, Hirano A, Umeno J, Fuyuno Y, Li D, Nakano T, Izumiyama Y, Ichikawa R, Hiramoto K, Moroi R, Kuroha M, Kanazawa Y, Shiga H, Tokunaga K, Nakamura M, Esaki M, Matsumoto T, McGovern DPB, Nagasaki M, Kinouchi Y, Masamune AGenetic Analysis of Ulcerative Colitis in Japanese Individuals Using Population-specific SNP Array.Inflamm Bowel Dis ( 2020) 26(8): 1177-1187PMID : 32072174
• Shiga H, Abe I, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kakuta Y, Endo K, Kinouchi Y, Masamune ASerum C-reactive protein and albumin are useful biomarkers for tight control management of Crohn's disease in Japan.Sci Rep ( 2020) 10(1): 511PMID : 31949246
• Moroi R, Shiga H, Kuroha M, Kanazawa Y, Nochioka K, Kakuta Y, Kinouchi Y, Masamune AEndoscopic radial incision and cutting for Crohn's Disease-associated intestinal stricture: a pilot study.Endosc Int Open ( 2020) 8(1): E81-E86PMID : 31921989
• Kakuta Y, Izumiyama Y, Okamoto D, Nakano T, Ichikawa R, Naito T, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Kudo H, Minegishi N, Kawai Y, Tokunaga K, Nagasaki M, Kinouchi Y, Suzuki Y, Masamune ACorrection to: High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype.J Gastroenterol ( 2020) 55(1): 132PMID : 31768800
• Tatsumi G, Kawahara M, Imai T, Nishishita-Asai A, Nishida A, Inatomi O, Yokoyama A, Kakuta Y, Kito K, Andoh AThiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15^R138C knock-in mice.Leukemia ( 2020) 34(3): 882-894PMID : 31645647
• Kakuta Y, Izumiyama Y, Okamoto D, Nakano T, Ichikawa R, Naito T, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Kudo H, Minegishi N, Kawai Y, Tokunaga K, Nagasaki M, Kinouchi Y, Suzuki Y, Masasmune AHigh-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype.J Gastroenterol ( 2020) 55(1): 67-77PMID : 31641873

2019年(5件)

• Takeda K, Kikuchi K, Kanazawa Y, Yamasaki K, Aiba SUstekinumab treatment for hidradenitis suppurativa.J Dermatol ( 2019) 46(12): 1215-1218PMID : 31638283
• Kanehara K, Ohnuma S, Kanazawa Y, Sato K, Kokubo S, Suzuki H, Karasawa H, Suzuki T, Suzuki C, Naitoh T, Unno M, Abe TThe indole compound MA-35 attenuates tumorigenesis in an inflammation-induced colon cancer model.Sci Rep ( 2019) 9(1): 12739PMID : 31484999
• Moroi R, Endo K, Yamamoto K, Naito T, Onodera M, Kuroha M, Kanazawa Y, Kimura T, Kakuta Y, Masamune A, Kinouchi Y, Shimosegawa TLong-term prognosis of Japanese patients with biologic-naïve Crohn's disease treated with anti-tumor necrosis factor-α antibodies.Intest Res ( 2019) 17(1): 94-106PMID : 30508475
• Kakuta Y, Kawai Y, Naito T, Hirano A, Umeno J, Fuyuno Y, Liu Z, Li D, Nakano T, Izumiyama Y, Ichikawa R, Okamoto D, Nagai H, Matsumoto S, Yamamoto K, Yokoyama N, Chiba H, Shimoyama Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Yasuda J, Esaki M, Tokunaga K, Nakamura M, Matsumoto T, McGovern DPB, Nagasaki M, Kinouchi Y, Shimosegawa T, Masamune AA Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn's Disease in Japanese Individuals.J Crohns Colitis ( 2019) 13(5): 648-658PMID : 30500874
• Onochi K, Shiga H, Takahashi S, Watanabe N, Fukuda S, Ishioka M, Koizumi S, Matsuhasi T, Jin M, Iijima KRisk Factors Linking Esophageal Squamous Cell Carcinoma With Head and Neck Cancer or Gastric Cancer.J Clin Gastroenterol ( 2019) 53(4): e164-e170PMID : 29498952

2018年(14件)

• Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, Targan SR, Shih DQInflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome.Mucosal Immunol ( 2018) 11(5): 1466-1476PMID : 29988118
• Kakuta Y, Kawai Y, Okamoto D, Takagawa T, Ikeya K, Sakuraba H, Nishida A, Nakagawa S, Miura M, Toyonaga T, Onodera K, Shinozaki M, Ishiguro Y, Mizuno S, Takahara M, Yanai S, Hokari R, Nakagawa T, Araki H, Motoya S, Naito T, Moroi R, Shiga H, Endo K, Kobayashi T, Naganuma M, Hiraoka S, Matsumoto T, Nakamura S, Nakase H, Hisamatsu T, Sasaki M, Hanai H, Andoh A, Nagasaki M, Kinouchi Y, Shimosegawa T, Masamune A, Suzuki YNUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.J Gastroenterol ( 2018) 53(9): 1065-1078PMID : 29923122
• Miyazawa T, Shiga H, Kinouchi Y, Takahashi S, Tominaga G, Takahashi H, Takagi S, Obana N, Kikuchi T, Omori S, Sato Y, Takahashi S, Umemura K, Endo K, Kakuta Y, Matsuura M, Kimura T, Kuroha M, Shimosegawa TLong-term course of inflammatory bowel disease after the Great East Japan Earthquake.J Gastroenterol Hepatol ( 2018) 33(12): 1956-1960PMID : 29791048
• Shimoyama Y, Tamai K, Shibuya R, Nakamura M, Mochizuki M, Yamaguchi K, Kakuta Y, Kinouchi Y, Sato I, Kudo A, Shimosegawa T, Satoh KPeriostin attenuates tumor growth by inducing apoptosis in colitis-related colorectal cancer.Oncotarget ( 2018) 9(28): 20008-20017PMID : 29731999
• Naito T, Yokoyama N, Kakuta Y, Ueno K, Kawai Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Nagasaki M, Masamune A, Kinouchi Y, Shimosegawa TClinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.J Gastroenterol Hepatol ( 2018) 33(11): 1873-1881PMID : 29603369
• Chiba H, Kakuta Y, Kinouchi Y, Kawai Y, Watanabe K, Nagao M, Naito T, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Nagasaki M, Unno M, Shimosegawa TAllele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease.PLoS One ( 2018) 13(3): e0194036PMID : 29547621
• Endo K, Fujishima F, Kuroha M, Moroi R, Onodera M, Naito T, Kanazawa Y, Kimura T, Shiga H, Kakuta Y, Kinouchi Y, Shimosegawa TEffective and less invasive diagnostic strategy for gastrointestinal GVHD.Endosc Int Open ( 2018) 6(3): E281-E291PMID : 29507868
• Onodera M, Endo K, Naito T, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Kakuta Y, Negoro K, Kinouchi Y, Shimosegawa TTacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours.Digestion ( 2018) 97(1): 90-96PMID : 29393157
• Fukushima K, Sugita A, Futami K, Takahashi KI, Motoya S, Kimura H, Yoshikawa S, Kinouchi Y, Iijima H, Endo K, Hibi T, Watanabe M, Sasaki I, Suzuki YPostoperative therapy with infliximab for Crohn's disease: a 2-year prospective randomized multicenter study in Japan.Surg Today ( 2018) 48(6): 584-590PMID : 29383596
• Kusaka J, Shiga H, Kuroha M, Kimura T, Kakuta Y, Endo K, Kinouchi Y, Shimosegawa TResidual Lesions on Capsule Endoscopy Is Associated with Postoperative Clinical Recurrence in Patients with Crohn's Disease.Dig Dis Sci ( 2018) 63(3): 768-774PMID : 29380174
• Umeno J, Esaki M, Hirano A, Fuyuno Y, Ohmiya N, Yasukawa S, Hirai F, Kochi S, Kurahara K, Yanai S, Uchida K, Hosomi S, Watanabe K, Hosoe N, Ogata H, Hisamatsu T, Nagayama M, Yamamoto H, Abukawa D, Kakuta F, Onodera K, Matsui T, Hibi T, Yao T, Kitazono T, Matsumoto TClinical features of chronic enteropathy associated with SLCO2A1 gene: a new entity clinically distinct from Crohn's disease.J Gastroenterol ( 2018) 53(8): 907-915PMID : 29313109
• Kakuta Y, Kinouchi Y, Shimosegawa TPharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.J Gastroenterol ( 2018) 53(2): 172-180PMID : 29192347
• Watanabe K, Matsumoto T, Hisamatsu T, Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi TClinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease.Clin Gastroenterol Hepatol ( 2018) 16(4): 542-549.e1PMID : 29104132
• Tanaka H, Kamata N, Yamada A, Endo K, Fujii T, Yoshino T, Sugaya T, Yokoyama Y, Bamba S, Umeno J, Yanai Y, Ishii M, Kawaguchi T, Shinzaki S, Toya Y, Kobayashi T, Nojima M, Hibi TLong-term retention of adalimumab treatment and associated prognostic factors for 1189 patients with Crohn's disease.J Gastroenterol Hepatol ( 2018) 33(5): 1031-1038PMID : 29087616

2017年(12件)

• Nakase H, Motoya S, Matsumoto T, Watanabe K, Hisamatsu T, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi TSignificance of measurement of serum trough level and anti-drug antibody of adalimumab as personalised pharmacokinetics in patients with Crohn's disease: a subanalysis of the DIAMOND trial.Aliment Pharmacol Ther ( 2017) 46(9): 873-882PMID : 28884856
• Chiba H, Endo K, Izumiyama Y, Nakano T, Okamoto D, Ichikawa R, Nagai H, Matsumoto S, Yokoyama N, Yamamoto K, Shimoyama Y, Naito T, Onodera M, Kusaka J, Hiramoto K, Kuroha M, Kanazawa Y, Kimura T, Kakuta Y, Kinouchi Y, Shimosegawa TUsefulness of a peripherally inserted central catheter for total parenteral nutrition in patients with inflammatory bowel disease.Nihon Shokakibyo Gakkai Zasshi ( 2017) 114(9): 1639-1648PMID : 28883293
• Kusaka J, Shiga H, Kuroha M, Kimura T, Kakuta Y, Endo K, Kinouchi Y, Shimosegawa TRisk factors associated with postoperative recurrence and repeat surgery in Japanese patients with Crohn's disease.Int J Colorectal Dis ( 2017) 32(10): 1407-1413PMID : 28735411
• Moroi R, Kakuta Y, Endo K, Kuroha M, Kayaba S, Kinouchi Y, Shimosegawa TEndoscopic removal of migrated colonic self-expandable metallic stent using a sliding tube.Endoscopy ( 2017) 49(10): E240-E241PMID : 28719932
• Sato T, Takagawa T, Kakuta Y, Nishio A, Kawai M, Kamikozuru K, Yokoyama Y, Kita Y, Miyazaki T, Iimuro M, Hida N, Hori K, Ikeuchi H, Nakamura SNUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases.Intest Res ( 2017) 15(3): 328-337PMID : 28670229
• Shiga H, Ohba R, Matsuhashi T, Jin M, Kuroha M, Endo K, Moroi R, Kayaba S, Iijima KFeasibility of colorectal endoscopic submucosal dissection (ESD) carried out by endoscopists with no or little experience in gastric ESD.Dig Endosc ( 2017) 29 Suppl 2 58-65PMID : 28425662
• Liu TC, Naito T, Liu Z, VanDussen KL, Haritunians T, Li D, Endo K, Kawai Y, Nagasaki M, Kinouchi Y, McGovern DP, Shimosegawa T, Kakuta Y, Stappenbeck TSLRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients.JCI Insight ( 2017) 2(6): e91917PMID : 28352666
• Suzuki T, Seki S, Hiramoto K, Naganuma E, Kobayashi EH, Yamaoka A, Baird L, Takahashi N, Sato H, Yamamoto MHyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.Nat Commun ( 2017) 8 14577PMID : 28233855
• Kakuta Y, Kimura T, Negoro K, Kuroha M, Shiga H, Endo K, Kinouchi Y, Shimosegawa TIncreased expression of IL12B mRNA transcribed from the risk haplotype for Crohn's disease is a risk factor for disease relapse in Japanese patients.J Gastroenterol ( 2017) 52(12): 1230-1239PMID : 28229296
• Onodera M, Endo K, Kakuta Y, Kuroha M, Kimura T, Hiramoto K, Kanazawa Y, Negoro K, Shiga H, Kinouchi Y, Shimosegawa TATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis.J Gastroenterol Hepatol ( 2017) 32(9): 1562-1569PMID : 28135009
• Zhang H, Zheng L, McGovern DP, Hamill AM, Ichikawa R, Kanazawa Y, Luu J, Kumagai K, Cilluffo M, Fukata M, Targan SR, Underhill DM, Zhang X, Shih DQMyeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis.J Immunol ( 2017) 198(5): 2133-2146PMID : 28130498
• Kim HS, Cheon JH, Jung ES, Park J, Aum S, Park SJ, Eun S, Lee J, Rüther U, Yeo GSH, Ma M, Park KS, Naito T, Kakuta Y, Lee JH, Kim WH, Lee MGA coding variant in <i>FTO</i> confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD.Gut ( 2017) 66(11): 1926-1935PMID : 27558924

2016年(5件)

• Moroi R, Endo K, Ichikawa R, Takahashi S, Shiroki T, Shinkai H, Ishiyama F, Kayaba SThree cases of endoscopic resection for synchronous early colon cancers after self-expandable metallic stent placement for obstructive colon cancer.Endosc Int Open ( 2016) 4(9): E970-3PMID : 27652303
• Tadano T, Kakuta Y, Hamada S, Shimodaira Y, Kuroha M, Kawakami Y, Kimura T, Shiga H, Endo K, Masamune A, Takahashi S, Kinouchi Y, Shimosegawa TMicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6.World J Gastrointest Oncol ( 2016) 8(7): 532-42PMID : 27559432
• Chiba H, Endo K, Fujishima F, Ohtsuka H, Naitoh T, Kuroha M, Kimura T, Shiga H, Kakuta Y, Kinouchi Y, Unno M, Shimosegawa TA case of a ruptured submucosal aneurysm of the small intestine identified using double-balloon enteroscopy.Clin J Gastroenterol ( 2016) 9(2): 49-54PMID : 26993305
• Endo K, Onodera M, Shiga H, Kuroha M, Kimura T, Hiramoto K, Kakuta Y, Kinouchi Y, Shimosegawa TA Comparison of Short- and Long-Term Therapeutic Outcomes of Infliximab- versus Tacrolimus-Based Strategies for Steroid-Refractory Ulcerative Colitis.Gastroenterol Res Pract ( 2016) 2016 3162595PMID : 26904108
• Kakuta Y, Naito T, Onodera M, Kuroha M, Kimura T, Shiga H, Endo K, Negoro K, Kinouchi Y, Shimosegawa TNUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD.Pharmacogenomics J ( 2016) 16(3): 280-5PMID : 26076924

2015年(3件)

• Moroi R, Endo K, Kinouchi Y, Shiga H, Kakuta Y, Kuroha M, Kanazawa Y, Shimodaira Y, Horiuchi T, Takahashi S, Shimosegawa TErratum to: FCGR3A-158 polymorphism influences the biological response to infliximab in Crohn's disease through affecting the ADCC activity.Immunogenetics ( 2015) 67(9): 545PMID : 26245508
• Shiga H, Kuroha M, Endo K, Kimura T, Kakuta Y, Kinouchi Y, Kayaba S, Shimosegawa TColorectal endoscopic submucosal dissection (ESD) performed by experienced endoscopists with limited experience in gastric ESD.Int J Colorectal Dis ( 2015) 30(12): 1645-52PMID : 26243470
• Naito T, Shiga H, Endo K, Kuroha M, Kakuta Y, Kinouchi Y, Shimosegawa TDe novo Crohn's disease following orthotopic liver transplantation: a case report and literature review.Intern Med ( 2015) 54(2): 199-204PMID : 25743012

2014年(9件)

• Kawakami Y, Endo K, Ishii T, Haneda S, Fujishima F, Kakuta Y, Shiga H, Kinouchi Y, Shimosegawa TIleocecal ulcers accompanied by relapsing polychondritis: a case report.Springerplus ( 2014) 3 714PMID : 25674454
• Moroi R, Endo K, Kuhroha M, Shiga H, Kakuta Y, Kinouchi Y, Shimosegawa TAcute onset collagenous colitis with unique endoscopic findings.Case Rep Gastrointest Med ( 2014) 2014 986092PMID : 25610672
• Moroi R, Endo K, Ichikawa R, Nagai H, Shinkai H, Kimura T, Ishiyama F, Yaguchi K, Kayaba S, Shimosegawa TThe Effectiveness of Self-Expandable Metallic Stent Insertion in Treating Right-Sided Colonic Obstruction: A Comparison between SEMS and Decompression Tube Placement and an Investigation of the Safety and Difficulties of SEMS Insertion in Right Colons.Gastroenterol Res Pract ( 2014) 2014 372918PMID : 25580111
• Endo K, Moroi R, Sugimura M, Fujishima F, Naitoh T, Tanaka N, Shiga H, Kakuta Y, Takahashi S, Kinouchi Y, Shimosegawa TRefractory sclerosing mesenteritis involving the small intestinal mesentery: a case report and literature review.Intern Med ( 2014) 53(13): 1419-27PMID : 24990334
• Hiramoto K, Satoh H, Suzuki T, Moriguchi T, Pi J, Shimosegawa T, Yamamoto MMyeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.Cancer Prev Res (Phila) ( 2014) 7(8): 835-44PMID : 24866179
• Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SRInhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis.Mucosal Immunol ( 2014) 7(6): 1492-503PMID : 24850426
• Shimodaira Y, Takahashi S, Kinouchi Y, Endo K, Shiga H, Kakuta Y, Kuroha M, Shimosegawa TModulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells.Biochem Biophys Res Commun ( 2014) 445(2): 524-33PMID : 24565834
• Shiga H, Endo K, Kuroha M, Kakuta Y, Takahashi S, Kinouchi Y, Shimosegawa TEndoscopic submucosal dissection for colorectal neoplasia during the clinical learning curve.Surg Endosc ( 2014) 28(7): 2120-8PMID : 24515262
• Avitzur Y, Guo C, Mastropaolo LA, Bahrami E, Chen H, Zhao Z, Elkadri A, Dhillon S, Murchie R, Fattouh R, Huynh H, Walker JL, Wales PW, Cutz E, Kakuta Y, Dudley J, Kammermeier J, Powrie F, Shah N, Walz C, Nathrath M, Kotlarz D, Puchaka J, Krieger JR, Racek T, Kirchner T, Walters TD, Brumell JH, Griffiths AM, Rezaei N, Rashtian P, Najafi M, Monajemzadeh M, Pelsue S, McGovern DP, Uhlig HH, Schadt E, Klein C, Snapper SB, Muise AMMutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.Gastroenterology ( 2014) 146(4): 1028-39PMID : 24417819

2013年(6件)

• Endo K, Moroi R, Shiga H, Takahashi S, Kakuta Y, Kinouchi Y, Shimosegawa TUnique findings on endoscopy with narrow-band imaging in colonic lesions of Henoch-Schönlein purpura.Endoscopy ( 2013) 45 Suppl 2 UCTN E65-6PMID : 23526521
• Shiga H, Miyazawa T, Kinouchi Y, Takahashi S, Tominaga G, Takahashi H, Takagi S, Obana N, Kikuchi T, Oomori S, Nomura E, Shiraki M, Sato Y, Takahashi S, Umemura K, Yokoyama H, Endo K, Kakuta Y, Aizawa H, Matsuura M, Kimura T, Kuroha M, Shimosegawa TLife-event stress induced by the Great East Japan Earthquake was associated with relapse in ulcerative colitis but not Crohn's disease: a retrospective cohort study.BMJ Open ( 2013) 3(2):PMID : 23396562
• Moroi R, Endo K, Kinouchi Y, Shiga H, Kakuta Y, Kuroha M, Kanazawa Y, Shimodaira Y, Horiuchi T, Takahashi S, Shimosegawa TFCGR3A-158 polymorphism influences the biological response to infliximab in Crohn's disease through affecting the ADCC activity.Immunogenetics ( 2013) 65(4): 265-71PMID : 23358932
• Endo K, Takahashi S, Shiga H, Kakuta Y, Kinouchi Y, Shimosegawa TShort and long-term outcomes of endoscopic balloon dilatation for Crohn's disease strictures.World J Gastroenterol ( 2013) 19(1): 86-91PMID : 23326167
• Umemura K, Takagi S, Shimada T, Masuda T, Shiga H, Takahashi S, Takahashi S, Kinouchi Y, Shibuya D, Shimosegawa TPrognostic and diagnostic significance of tumor budding associated with β-catenin expression in submucosal invasive colorectal carcinoma.Tohoku J Exp Med ( 2013) 229(1): 53-9PMID : 23238650
• Shiga H, Kajiura T, Shinozaki J, Suzuki M, Takagi S, Kinouchi Y, Takahashi S, Shimosegawa TAuthor reply: Comment to Dig Liver Dis ( 2013) 45(2): 177-8PMID : 23079402

2012年(4件)

• Endo K, Kuroha M, Shiga H, Kakuta Y, Takahashi S, Kinouchi Y, Shimosegawa TTwo cases of diffuse duodenitis associated with ulcerative colitis.Case Rep Gastrointest Med ( 2012) 2012 396521PMID : 23119193
• Shiga H, Kajiura T, Shinozaki J, Takagi S, Kinouchi Y, Takahashi S, Negoro K, Endo K, Kakuta Y, Suzuki M, Shimosegawa TChanges of faecal microbiota in patients with Crohn's disease treated with an elemental diet and total parenteral nutrition.Dig Liver Dis ( 2012) 44(9): 736-42PMID : 22622202
• Yamada-Fujiwara M, Miyamura K, Fujiwara T, Tohmiya Y, Endo K, Onishi Y, Ishizawa K, Kameoka J, Ito M, Harigae HDiagnosis of intestinal graft-versus-host disease and thrombotic microangiopathy after allogeneic stem cell transplantation.Tohoku J Exp Med ( 2012) 227(1): 31-7PMID : 22531159
• Hibi T, Sakuraba A, Watanabe M, Motoya S, Ito H, Motegi K, Kinouchi Y, Takazoe M, Suzuki Y, Matsumoto T, Kawakami K, Matsumoto T, Hirata I, Tanaka S, Ashida T, Matsui TRetrieval of serum infliximab level by shortening the maintenance infusion interval is correlated with clinical efficacy in Crohn's disease.Inflamm Bowel Dis ( 2012) 18(8): 1480-7PMID : 21987418

2011年(2件)

• Kuroha M, Endo K, Sato Y, Shiga H, Kakuta Y, Takahashi S, Kinouchi Y, Shimosegawa TMagnifying endoscopy findings in follicular lymphoma of the rectum using narrow band imaging.Endoscopy ( 2011) 43 Suppl 2 UCTN E346-7PMID : 22020720
• Arai T, Kakuta Y, Kinouchi Y, Kimura T, Negoro K, Aihara H, Endo K, Shiga H, Kanazawa Y, Kuroha M, Moroi R, Nagasawa H, Shimodaira Y, Takahashi S, Shimosegawa TIncreased expression of NKX2.3 mRNA transcribed from the risk haplotype for ulcerative colitis in the involved colonic mucosa.Hum Immunol ( 2011) 72(7): 587-91PMID : 21514341

2010年(4件)

• Kanazawa Y, Saito Y, Supriatna Y, Tezuka H, Kotani T, Murata Y, Okazawa H, Ohnishi H, Kinouchi Y, Nojima Y, Ohteki T, Shimosegawa T, Matozaki TRole of SIRPα in regulation of mucosal immunity in the intestine.Genes Cells ( 2010) 15(12): 1189-200PMID : 21040253
• Takahashi S, Takagi S, Shiga H, Umemura K, Endo K, Kakuta Y, Takahashi S, Kinouchi Y, Shimosegawa TScheduled maintenance therapy with infliximab improves the prognosis of Crohn's disease: a single center prospective cohort study in Japan.Tohoku J Exp Med ( 2010) 220(3): 207-15PMID : 20208416
• Shiga H, Takagi S, Inoue R, Kinouchi Y, Ohkubo T, Takahashi S, Negoro K, Yokoyama H, Kato S, Fukushima K, Hiwatashi N, Shimosegawa TWhat determines the later clinical course of patients who do not undergo colectomy at the first attack? A Japanese cohort study on ulcerative colitis.Digestion ( 2010) 81(2): 104-12PMID : 20068310
• Endo K, Kinouchi Y, Kakuta Y, Ueki N, Takahashi S, Shimosegawa TInvolvement of NF-kappa B pathway in TL1A gene expression induced by lipopolysaccharide.Cytokine ( 2010) 49(2): 215-20PMID : 19815424

2009年(4件)

• Asano K, Matsushita T, Umeno J, Hosono N, Takahashi A, Kawaguchi T, Matsumoto T, Matsui T, Kakuta Y, Kinouchi Y, Shimosegawa T, Hosokawa M, Arimura Y, Shinomura Y, Kiyohara Y, Tsunoda T, Kamatani N, Iida M, Nakamura Y, Kubo MA genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.Nat Genet ( 2009) 41(12): 1325-9PMID : 19915573
• Moroi R, Sato Y, Sakurai T, Kin S, Iwabuchi T, Oyauchi M, Igarashi T, Obana NMultiple hemorrhagic duodenal ulcers caused by cytomegalovirus infection.Endoscopy ( 2009) 41 Suppl 2 E216-7PMID : 19757361
• Aizawa H, Kinouchi Y, Negoro K, Nomura E, Imai G, Takahashi S, Takagi S, Kakuta Y, Tosa M, Mochida A, Matsumura Y, Endo K, Shimosegawa THLA-B is the best candidate of susceptibility genes in HLA for Japanese ulcerative colitis.Tissue Antigens ( 2009) 73(6): 569-74PMID : 19493234
• Kakuta Y, Ueki N, Kinouchi Y, Negoro K, Endo K, Nomura E, Takagi S, Takahashi S, Shimosegawa TTNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells.Hum Mol Genet ( 2009) 18(6): 1089-98PMID : 19124533

2008年(3件)

• Umemura K, Takagi S, Ishigaki Y, Iwabuchi M, Kuroki S, Kinouchi Y, Shimosegawa TGastrointestinal polyposis with esophageal polyposis is useful for early diagnosis of Cowden's disease.World J Gastroenterol ( 2008) 14(37): 5755-9PMID : 18837096
• Sato Y, Takagi S, Aizawa H, Yokoyama H, Takahashi S, Kakuta Y, Tosa M, Mochida A, Nomura E, Takahashi S, Kinouchi Y, Shimosegawa TUseful endoscopic findings for early diagnosis of ulcerative colitis associated colorectal cancer.Endoscopy ( 2008) 40 Suppl 2 E71-2PMID : 18633889
• Matsumura Y, Kinouchi Y, Nomura E, Negoro K, Kakuta Y, Endo K, Aizawa H, Takagi S, Takahashi S, Shimosegawa THLA-DRB1 alleles influence clinical phenotypes in Japanese patients with ulcerative colitis.Tissue Antigens ( 2008) 71(5): 447-52PMID : 18416774

膵臓グループ

2026年(5件)

• Yoshida J, Ohishi T, Momose I, Ohba SI, Kurosawa K, Harakawa A, Inoue H, Senoo M, Tatsuda D, Abe H, Masamune A, Kawada MSUSD2 Promotes Metastasis and Primary Tumor Growth in Pancreatic Cancer Cells via Integrin-FAK Signaling Activation.Cancer Sci ( 2026) PMID : 41513453
• Naitoh I, Nakazawa T, Kubota K, Nishino T, Nakamura A, Inoue D, Sano T, Kikuta K, Kurita Y, Chiba K, Ikeura T, Matsubayashi H, Ishikawa T, Kuwatani M, Kamisawa T, Yasuda I, Kawano M, Masamune AMulticenter Validation Study of the Clinical Diagnostic Criteria for IgG4-Related Sclerosing Cholangitis 2020 in Japan.J Hepatobiliary Pancreat Sci ( 2026) PMID : 41500843
• Sato H, Aoki S, Iseki M, Ando M, Hayashi S, Yoshimachi S, Kusaka A, Shimura M, Douchi D, Miura T, Maeda S, Ishida M, Mizuma M, Masamune A, Unno MCharacteristics of late recurrences after hepatectomy for perihilar cholangiocarcinoma: a single-center cohort study.BMC Surg ( 2026) PMID : 41495717
• Matsumoto R, Kikuta K, Takikawa T, Nakai Y, Takenaka M, Oki K, Ohno E, Ito K, Fujimori N, Katanuma A, Masuda A, Hori Y, Ikeura T, Suzuki R, Yamamoto S, Sogame Y, Kawashima H, Ito T, Okuwaki K, Itoi T, Takayama Y, Nakamura A, Terai S, Matsumoto K, Kuwatani M, Kishiwada M, Shigekawa M, Matsumori T, Inatomi O, Hatta W, Irisawa A, Unno M, Takeyama Y, Masamune AMortality and cancer risk in patients with chronic pancreatitis in japan: insights into the importance of surveillance for pancreatic cancer.J Gastroenterol ( 2026) 61(1): 105-116PMID : 41251799
• Masuda A, Notohara K, Kodama Y, Inoue D, Umemura T, Ikeura T, Kanno A, Iwasaki E, Fujimori N, Seno H, Kikuta K, Nakase H, Uehara T, Abe S, Tsujimae M, Nakamura S, Kawano M, Masamune AClinical manifestations of immunoglobulin G4-related gastrointestinal disease: a nationwide multicenter retrospective study.J Gastroenterol ( 2026) 61(1): 16-26PMID : 41148248

2025年(26件)

• Abe T, Nakamura M, Morizane C, Yoshida M, Kitano M, Ohtsuka T, Nakata K, Someya M, Mizuno N, Nakai Y, Ozaka M, Hanada K, Masamune AClinical Practice Guidelines for Pancreatic Cancer 2025 From the Japan Pancreas Society: A Synopsis.Pancreas ( 2025) PMID : 41342569
• Yamaguchi-Tanaka M, Sasaki T, Uemura K, Tajima Y, Kato S, Asakura T, Takagi K, Yamazaki Y, Masamune A, Miyata T, Suzuki TArtificial Intelligence for Breast Carcinoma Detection in Histopathological Images Based on Single Shot Multibox Detector in Intraoperative Rapid Diagnosis.Tohoku J Exp Med ( 2025) PMID : 41338964
• Nishiyama T, Tazawa H, Nagai Y, Shoji R, Kajiwara Y, Hashimoto N, Takahashi Y, Kikuchi S, Kuroda S, Ohara T, Noma K, Yoshida R, Umeda Y, Tanaka HY, Kano MR, Masamune A, Urata Y, Kagawa S, Fujiwara Tp53-armed oncolytic adenovirus induces apoptosis in pancreatic cancer-associated stellate cells via macropinocytosis.Cancer Gene Ther ( 2025) PMID : 41315733
• Masamune A, Masson E, Zou WB, Rygiel AM, Chowdhury SD, Kikuta K, Hayashi H, Sasaki A, Nakasuji H, Matsumoto R, Takikawa T, Xu Y, Jie R, Sekino Y, Abe T, Hatta W, Niihori T, Aoki Y, Sakaguchi R, Mori Y, Rebours V, Buscail L, Wang YC, Kurien RT, Visweswariah SS, Rosendahl J, Ferec C, Oracz G, Witt H, Liao Z, Chen JM, Hamada STRPV6-related pancreatitis: natural history and the impact of the pancreas-specific deletion on pancreatitis in mice.J Gastroenterol ( 2025) PMID : 41247519
• Zhang YO, Iwasaki T, Kawaguchi T, Takahashi H, Kawaguchi S, Kanno A, Yamaguchi I, Kubota K, Dobashi H, Nagasaki M, Yamamoto M, Takahashi M, Shimizu M, Ikeura T, Matsui S, Kanda M, Nakamura K, Yokoyama K, Azumi A, Masaki Y, Mizushima I, Kurita Y, Seno H, Origuchi T, Yazumi S, Hirano K, Masamune A, Mizuno N, Shimada H, Moriyama M, Hori Y, Kodama Y, Saeki T, Kin T, Kawanami C, Asada M, Akamizu T, Nakamura A, Oshima K, Tanaka Y, Yoshifuji H, Kamisawa T, Kimura T, Umehara H, Ishikawa H, Chiba T, Okazaki K, Mimori T, Nakamura S, Kawano M, Matsuda FIgG4-related disease in the Japanese population: a whole-genome sequencing study.Lancet Rheumatol ( 2025) PMID : 41197642
• Ohira M, Kitamura M, Iwasaki H, Ohta-Okano H, Tsujii H, Nakamura R, Nakazawa T, Nishiguchi A, Yamamoto M, Osada K, Toyooka S, Cabral H, Masamune A, Kano MR, Tanaka HYCollagen Signaling via DDR1 Exacerbates Barriers to Macromolecular Drug Delivery in a 3D Model of Pancreatic Cancer Fibrosis.Small ( 2025) e06926PMID : 41170605
• Peiffer R, Laverdeur E, Gaigneaux A, Boumahd Y, Gullo C, Rademaker G, Crake R, Lavergne A, Maloujahmoum N, Agirman F, Herfs M, Masamune A, Letellier E, Bellahcène A, Peulen OTargeting myoferlin in ER/Golgi vesicle trafficking reprograms pancreatic cancer-associated fibroblasts.EMBO J ( 2025) 44(22): 6425-6465PMID : 41062852
• Watanabe H, Kubo S, Fujishima F, Sasaki K, Takahashi M, Kume K, Yamazaki T, Toyama Y, Masamune A, Sasano H, Suzuki TA Case Report of Alpha-Fetoprotein-Producing Pancreatic Neuroendocrine Tumor and Review of the Literature.Int J Surg Pathol ( 2025) 10668969251376699PMID : 41051970
• Zhu M, Douchi D, Murakami K, Itoh T, Migita S, Rikiyama N, Hayashi S, Kokumai T, Sato H, Yoshimachi S, Kusaka A, Shimura M, Nakayama S, Aoki S, Iseki M, Miura T, Maeda S, Ishida M, Ohtsuka H, Mizuma M, Nakagawa K, Masamune A, Furukawa T, Unno MMolecular insights into HER2/ERBB2 amplification and carcinogenesis in gallbladder cancer associated with pancreaticobiliary maljunction.J Gastroenterol ( 2025) PMID : 41046276
• Miura T, Aoki S, Maeda S, Ishida M, Mizuma M, Kume K, Murakami K, Masamune A, Furukawa T, Kamei T, Unno MLaparoscopic enucleation vs. pancreatectomy for small pancreatic neuroendocrine neoplasms: long-term functional and oncological outcomes.Surg Endosc ( 2025) PMID : 40879775
• Manaka T, Tarasawa K, Takikawa T, Kikuta K, Matsumoto R, Tanaka Y, Sano T, Hamada S, Miura S, Kume K, Fujimori K, Fushimi K, Masamune AImpact of coronavirus disease 2019 on the clinical outcomes of acute pancreatitis: a nationwide observational study in Japan.Pancreatology ( 2025) 25(6): 823-831PMID : 40866153
• Abe T, Matsumoto R, Hamada S, Takikawa T, Kikuta K, Hayashi H, Sano T, Tanaka Y, Kataoka F, Sakano M, Manaka T, Sekino Y, Tanaka Y, Masuo T, Nakasuji H, Xu Y, Jie R, Miura S, Kume K, Unno M, Masamune AAlteration of Apolipoprotein A2 Isoforms is Associated with the Progression of Chronic Pancreatitis.Pancreas ( 2025) PMID : 40856765
• Kano T, Iseki M, Aoki S, Mizuma M, Murakami K, Kume K, Masamune A, Furukawa T, Kamei T, Unno MA case of FGFR2 fusion-positive pancreatic head tumor with difficult differential diagnosis between cholangiocarcinoma and pancreatic ductal adenocarcinoma.Clin J Gastroenterol ( 2025) 18(5): 980-987PMID : 40768166
• Tanaka Y, Masamune A, Matsumoto R, Takikawa T, Tanaka Y, Hamada S, Miura S, Kume K, Takeyama Y, Kikuta KNationwide epidemiological survey of acute pancreatitis in Japan, 2021: the impact of the COVID-19 pandemic and revised clinical guidelines.J Gastroenterol ( 2025) 60(11): 1437-1448PMID : 40745500
• Sano T, Kikuta K, Matsumoto R, Takikawa T, Hamada S, Miura S, Kume K, Masamune APrevalence and risk factors of skeletal muscle loss and sarcopenia in patients with autoimmune pancreatitis.Hepatobiliary Pancreat Dis Int ( 2025) 24(4): 396-403PMID : 40480899
• Ishida M, Maeda S, Hayashi S, Yoshimachi S, Sato H, Kusaka A, Shimura M, Aoki S, Iseki M, Douchi D, Miura T, Mizuma M, Kume K, Masamune A, Kamei T, Unno MA Case of Rendezvous Dilation under Laparotomy for Pancreaticojejunostomy Stricture after Pancreaticoduodenectomy.Surg Case Rep ( 2025) 11(1):PMID : 40386492
• Yonemura H, Kuwatani M, Nakajima K, Masamune A, Ogawa M, Sakamoto NTreatment of Pancreatic Cancer Using Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Combination with Anticancer Chemotherapeutic Drug.Cancers (Basel) ( 2025) 17(9):PMID : 40361512
• Manaka T, Takikawa T, Tarasawa K, Kikuta K, Matsumoto R, Tanaka Y, Sano T, Hamada S, Miura S, Kume K, Fujimori K, Fushimi K, Masamune ACurrent status and trends in ERCP and post-ERCP pancreatitis in Japan: a nationwide observational study.J Gastroenterol ( 2025) 60(8): 1036-1046PMID : 40314772
• Mukai S, Takeyama Y, Itoi T, Ikeura T, Irisawa A, Iwasaki E, Katanuma A, Kitamura K, Takenaka M, Hirota M, Mayumi T, Morizane T, Yasuda I, Ryozawa S, Masamune AClinical Practice Guidelines for post-ERCP pancreatitis 2023.Dig Endosc ( 2025) 37(6): 573-587PMID : 40132896
• Ikeura T, Takaori A, Kikuta K, Ito K, Takikawa T, Eguchi T, Inoue T, Hori Y, Nakamura K, Takenaka M, Sogame Y, Takagi T, Fujimori N, Yamamoto S, Nakamura A, Sakai T, Sakai A, Tamura T, Saito T, Fujita K, Kanno A, Hosono K, Iwata K, Irisawa A, Okamoto K, Kuwatani M, Naganuma M, Masamune A, Takeyama YComplete clearance of painless pancreatic stones with endotherapy prevents the progression of pancreatic parenchyma atrophy in patients with chronic pancreatitis: Multicenter cohort study.Dig Endosc ( 2025) 37(6): 638-650PMID : 40012465
• Yamashige D, Hijioka S, Shimizu Y, Yanagisawa A, Nakamura M, Hara K, Kitano M, Koshita S, Takikawa T, Kin T, Takenaka M, Hanada K, Ueki T, Itoi T, Yamada R, Ohtsuka T, Hirono S, Kanno A, Takeyama Y, Masamune AClinical impact of epithelial types on postoperative outcomes for intraductal papillary mucinous neoplasms: a multicenter retrospective study.J Gastroenterol ( 2025) 60(5): 658-670PMID : 39966119
• Tanaka A, Notohara K, Tobari M, Abe M, Umemura T, Takahashi A, Tsutsui A, Ito T, Tsuneyama K, Masamune A, Harada KI, Ohira H, Kawano MA clinicopathological study of IgG4-related autoimmune hepatitis and IgG4-hepatopathy.J Gastroenterol ( 2025) 60(5): 632-640PMID : 39921744
• Sano T, Kikuta K, Takikawa T, Matsumoto R, Okazaki K, Takeyama Y, Masamune ASerum IgG4-negative and IgG4-positive type 1 autoimmune pancreatitis present with different clinicopathological features: An analysis of a nationwide survey in Japan.Pancreatology ( 2025) 25(1): 82-88PMID : 39643518
• Yamamoto M, Kanda M, Mizushima I, Kanno A, Umemura T, Ikeura T, Kodama Y, Dobashi H, Tanaka Y, Masamune A, Moriyama M, Saeki T, Matsui S, Origuchi T, Masaki Y, Asada M, Umehara H, Seno H, Naitoh I, Yamamoto S, Iwasaki E, Kubota K, Tanoue S, Nishino T, Tsuboi H, Matsumoto Y, Isayama H, Goto H, Notohara K, Uchida K, Kawabe K, Yamada K, Kasashima S, Takahira M, Sato Y, Kawachi I, Yamaguchi I, Okazaki K, Nakamura S, Matsuda F, Ishikawa H, Kawano MClinical profile of IgG4-related disease in Japan based on the rare disease data registry.Immunol Med ( 2025) 48(3): 192-202PMID : 39607031
• Takikawa T, Kume K, Tanaka Y, Kikuta K, Ogata Y, Hatta W, Hamada S, Miura S, Matsumoto R, Sano T, Sasaki A, Hayashi H, Sakano M, Manaka T, Masamune ARisk Factors and a Prediction Model for Pain Recurrence After Pancreatic Stent Removal in Painful Chronic Pancreatitis.Pancreas ( 2025) 54(1): e30-e38PMID : 39259846
• Suzuki S, Omori Y, Ono Y, Hirose K, Itoh T, Karasaki H, Shimoda M, Nagakawa Y, Higuchi R, Endo I, Rikiyama T, Unno M, Fujii T, Sunagawa Y, Eguchi H, Sasanuma H, Akahori T, Okano K, Tani M, Hirano S, Shimizu Y, Kitago M, Mizuno S, Yamamoto T, Furukawa M, Ohtsuka M, Sugimoto M, Matsushita A, Hakamada K, Igarashi H, Kuroki T, Tanno S, Tsuji Y, Masamune A, Mizumoto K, Hirooka Y, Yamaue H, Okazaki K, Satoi S, Takeyama Y, Mizukami Y, Furukawa TThree Molecular Developmental Pathways of Remnant Pancreatic Cancer After Resection: A Nationwide Project Study of Japan Pancreas Society.Ann Surg ( 2025) 281(6): 1015-1025PMID : 39016004

2024年(13件)

• Tsunetoshi Y, Sanada F, Kanemoto Y, Shibata K, Masamune A, Taniyama Y, Yamamoto K, Morishita RA Role for Periostin Pathological Variants and Their Interaction with HSP70-1a in Promoting Pancreatic Cancer Progression and Chemoresistance.Int J Mol Sci ( 2024) 25(23):PMID : 39684914
• Yamaguchi-Tanaka M, Takagi K, Sato A, Yamazaki Y, Miyashita M, Masamune A, Suzuki TRegulation of Stromal Cells by Sex Steroid Hormones in the Breast Cancer Microenvironment.Cancers (Basel) ( 2024) 16(23):PMID : 39682229
• Ito S, Ando M, Aoki S, Soma S, Zhang J, Hirano N, Kashiwagi R, Murakami K, Yoshimachi S, Sato H, Kusaka A, Iseki M, Inoue K, Mizuma M, Kume K, Nakagawa K, Masamune A, Asano N, Yasuda J, Unno MUsefulness of multigene liquid biopsy of bile for identifying driver genes of biliary duct cancers.Cancer Sci ( 2024) 115(12): 4054-4063PMID : 39377143
• Sándor M, Scheers I, Masamune A, Witt H, LaRusch J, Chen JM, Németh BC, Geisz A, Uc A, Sahin-Tóth MAlphaMissense versus laboratory-based pathogenicity prediction of 13 novel missense CPA1 variants from pancreatitis cases.Gut ( 2024) PMID : 39256032
• Ohtsuka T, Maguchi H, Tokunaga S, Hijioka S, Takayama Y, Koshita S, Hanada K, Sudo K, Uehara H, Tanno S, Tada M, Kimura W, Nakamura M, Kin T, Kamata K, Masamune A, Iwashita T, Akahoshi K, Ueki T, Okamura K, Kato H, Kumagi T, Kawabe K, Yoshida K, Mukai T, Sakagami J, Hirono S, Abue M, Nakafusa T, Morita M, Shimosegawa T, Tanaka MProspective multicenter surveillance study of branch-duct intraductal papillary mucinous neoplasm of the pancreas; risk of dual carcinogenesis.Pancreatology ( 2024) 24(7): 1141-1151PMID : 39191596
• Kubota K, Iwasaki E, Ishikawa T, Kuwatani M, Takenaka M, Iwashita T, Masuda A, Ikeura T, Nakamura A, Tanaka A, Isayama H, Hirooka Y, Hirano K, Ryozawa S, Ogura T, Fujisawa T, Kurita Y, Kikuta K, Hayashi N, Masamune A, Yasuda IDiagnosis of isolated hilar-/extrahepatic-type IgG-4-related sclerosing cholangitis can be increased by improved recognition of this condition-A Japanese multicenter analysis.J Hepatobiliary Pancreat Sci ( 2024) 31(9): 647-657PMID : 39123289
• Hijioka S, Yamashige D, Esaki M, Honda G, Higuchi R, Masui T, Shimizu Y, Ohtsuka M, Kumamoto Y, Katanuma A, Gotohda N, Akita H, Unno M, Endo I, Yokoyama Y, Yamada S, Matsumoto I, Ohtsuka T, Hirano S, Yasuda H, Kawai M, Aoki T, Nakamura M, Hashimoto D, Rikiyama T, Horiguchi A, Fujii T, Mizuno S, Hanada K, Tani M, Hatori T, Ito T, Okuno M, Kagawa S, Tajima H, Ishii T, Sugimoto M, Onoe S, Takami H, Takada R, Miura T, Kurita Y, Kamei K, Mataki Y, Okazaki K, Takeyama Y, Yamaue H, Satoi SFactors Affecting Nonfunctioning Small Pancreatic Neuroendocrine Neoplasms and Proposed New Treatment Strategies.Clin Gastroenterol Hepatol ( 2024) 22(7): 1416-1426.e5PMID : 38615727
• Tanaka HY, Nakazawa T, Miyazaki T, Cabral H, Masamune A, Kano MRTargeting ROCK2 improves macromolecular permeability in a 3D fibrotic pancreatic cancer microenvironment model.J Control Release ( 2024) 369 283-295PMID : 38522816
• Takikawa T, Kikuta K, Sano T, Ikeura T, Fujimori N, Umemura T, Naitoh I, Nakase H, Isayama H, Kanno A, Kamata K, Kodama Y, Inoue D, Ido A, Ueki T, Seno H, Yasuda H, Iwasaki E, Nishino T, Kubota K, Arizumi T, Tanaka A, Uchida K, Matsumoto R, Hamada S, Nakamura S, Okazaki K, Takeyama Y, Masamune AMaintenance steroid therapy is associated with decreased risk of malignancy and better prognosis of patients with autoimmune pancreatitis: A multicenter cohort study in Japan.Pancreatology ( 2024) PMID : 38336506
• Yamashita Y, Shimokawa T, Ashida R, Hirooka Y, Iwashita T, Kato H, Kin T, Masamune A, Miwa H, Ohno E, Shiomi H, Sofuni A, Takenaka M, Kitano MProtocol for a Multi-Center Confirmatory Trial to Evaluate the Differential Diagnostic Performance of Contrast-Enhanced Ultrasonography Using Perflubutane in Patients with a Pancreatic Mass: A Multicenter Prospective Study.Diagnostics (Basel) ( 2024) 14(2):PMID : 38248007
• Matsumoto R, Kikuta K, Takikawa T, Sano T, Hamada S, Sasaki A, Sakano M, Hayashi H, Manaka T, Ikeda M, Miura S, Kume K, Masamune ASkeletal muscle mass and function are affected by pancreatic atrophy, pancreatic exocrine insufficiency and poor nutritional status in patients with chronic pancreatitis.Pancreatology ( 2024) PMID : 38216352
• Hirota M, Itoi T, Morizane T, Koiwai A, Yasuda I, Ryozawa S, Mukai S, Ikeura T, Irisawa A, Iwasaki E, Katanuma A, Kitamura K, Takenaka M, Ito T, Masamune A, Mayumi T, Takeyama YPostprocedure serum amylase or lipase levels predict postendoscopic retrograde cholangiopancreatography pancreatitis: Meta-analysis of diagnostic test accuracy studies and utility assessment.Dig Endosc ( 2024) 36(6): 670-687PMID : 37921041
• Ishiwatari H, Kawabata T, Kawashima H, Nakai Y, Miura S, Kato H, Shiomi H, Fujimori N, Ogura T, Inatomi O, Kubota K, Fujisawa T, Takenaka M, Mori H, Noguchi K, Fujii Y, Sugiura T, Ideno N, Nakafusa T, Masamune A, Isayama H, Sasahira NEndoscopic nasobiliary drainage versus endoscopic biliary stenting for preoperative biliary drainage in patients with malignant hilar biliary obstruction: Propensity score-matched multicenter comparative study.Dig Endosc ( 2024) 36(6): 726-734PMID : 37885412

2023年(12件)

• Ikeda M, Kikuta K, Hamada S, Takikawa T, Matsumoto R, Sano T, Sasaki A, Sakano M, Tarasawa K, Fujimori K, Fushimi K, Masamune ATrends and clinical characteristics of pediatric acute pancreatitis patients in Japan: A comparison with adult cases based on a national administrative inpatient database.Pancreatology ( 2023) 23(7): 797-804PMID : 37827972
• Iwama R, Miyashita H, Koketsu A, Kume K, Fujishima F, Masamune A, Takahashi TA case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report.BMC Oral Health ( 2023) 23(1): 595PMID : 37633917
• Kokumai T, Omori Y, Ishida M, Ohtsuka H, Mizuma M, Nakagawa K, Maeda C, Ono Y, Mizukami Y, Miura S, Kume K, Masamune A, Morikawa T, Unno M, Furukawa TGATA6 and CK5 Stratify the Survival of Patients With Pancreatic Cancer Undergoing Neoadjuvant Chemotherapy.Mod Pathol ( 2023) 36(5): 100102PMID : 36788090
• Tanaka HY, Nakazawa T, Enomoto A, Masamune A, Kano MRTherapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment.Cancers (Basel) ( 2023) 15(3):PMID : 36765684
• Itaya T, Sano M, Kajiwara I, Oshima Y, Kuramochi T, Kim J, Ichimaru Y, Kitajima O, Masamune A, Ijichi H, Ishii Y, Suzuki TMirogabalin improves cancer-associated pain but increases the risk of malignancy in mice with pancreatic cancer.Pain ( 2023) 164(7): 1545-1554PMID : 36701124
• Masson E, Ewers M, Paliwal S, Kume K, Scotet V, Cooper DN, Rebours V, Buscail L, Rouault K, Abrantes A, Aguilera Munoz L, Albouys J, Alric L, Amiot X, Archambeaud I, Audiau S, Bastide L, Baudon J, Bellaiche G, Bellon S, Bertrand V, Bideau K, Billiemaz K, Billioud C, Bonnefoy S, Borderon C, Bournet B, Breton E, Brugel M, Buscail L, Cadiot G, Camus M, Carpentier-Pourquier M, Chamouard P, Chaput U, Chen JM, Cholet F, Ciocan DM, Clavel C, Coffin B, Coimet-Berger L, Cosconea S, Creveaux I, Culetto A, Daboussi O, De Mestier L, Degand T, D'engremont C, Denis B, Dermine S, Desgrippes, Drouet D'Aubigny A, Enaud R, Fabre A, Férec C, Gargot D, Gelsi E, Gentilcore E, Gincul R, Ginglinger-Favre E, Giovannini M, Gomercic C, Gondran H, Grainville T, Grandval P, Grasset D, Grimaldi S, Grimbert S, Hagege H, Heissat S, Hentic O, Herber-Mayne A, Hervouet M, Hoibian S, Jacques J, Jais B, Kaassis M, Koch S, Lacaze E, Lacroute J, Lamireau T, Laurent L, Le Guillou X, Le Rhun M, Leblanc S, Levy P, Lievre A, Lorenzo D, Maire F, Marcel K, Masson E, Mauillon J, Morgant S, Moussata D, Muller N, Nambot S, Napoleon B, Olivier A, Pagenault M, Pelletier AL, Pennec O, Pinard F, Pioche M, Prost B, Queneherve L, Rebours V, Reboux N, Rekik S, Riachi G, Rohmer B, Roquelaure B, Rosa Hezode I, Rostain F, Saurin JC, Servais L, Stan-Iuga R, Subtil C, Tanneche J, Texier C, Thomassin L, Tougeron D, Vuitton L, Wallenhorst T, Wangerme M, Zanaldi H, Zerbib F, Bhaskar S, Kikuta K, Rao GV, Hamada S, Reddy DN, Masamune A, Chandak GR, Witt H, Férec C, Chen JMThe PRSS3P2 and TRY7 deletion copy number variant modifies risk for chronic pancreatitis.Pancreatology ( 2023) 23(1): 48-56PMID : 36517351
• Sano T, Kikuta K, Takikawa T, Matsumoto R, Hamada S, Sasaki A, Kataoka F, Ikeda M, Miura S, Kume K, Masamune AThe M-ANNHEIM-AiP-Activity-Score is useful for predicting relapse in patients with type 1 autoimmune pancreatitis.Pancreatology ( 2023) 23(1): 112-119PMID : 36509645
• Tomimaru Y, Eguchi H, Inoue Y, Nagakawa Y, Ohba A, Takami H, Unno M, Yamamoto T, Kawakatsu S, Hayashi T, Higuchi R, Kitagawa H, Hattori S, Fujii T, Hirooka Y, Igarashi H, Kitano M, Kuroki T, Masamune A, Shimizu Y, Tani M, Tanno S, Tsuji Y, Yamaue H, Satoi S, Takeyama YImpact of S-1 adjuvant chemotherapy longer than 6 months on survival in patients with resected pancreatic cancer: a nationwide survey by the Japan Pancreas Society based on real-world data.Cancer ( 2023) 129(5): 728-739PMID : 36504020
• Kubota K, Kamisawa T, Nakazawa T, Tanaka A, Naitoh I, Kurita Y, Takikawa H, Unno M, Kawa S, Masamune A, Nakamura S, Okazaki KReducing relapse through maintenance steroid treatment can decrease the cancer risk in patients with IgG4-sclerosing cholangitis: Based on a Japanese nationwide study.J Gastroenterol Hepatol ( 2023) 38(4): 556-564PMID : 36403136
• Ishiwatari H, Kawabata T, Kawashima H, Nakai Y, Miura S, Kato H, Shiomi H, Fujimori N, Ogura T, Inatomi O, Kubota K, Fujisawa T, Takenaka M, Mori H, Noguchi K, Fujii Y, Sugiura T, Ideno N, Nakafusa T, Masamune A, Isayama H, Sasahira NClinical Outcomes of Inside Stents and Conventional Plastic Stents as Bridge-to-Surgery Options for Malignant Hilar Biliary Obstruction.Dig Dis Sci ( 2023) 68(4): 1139-1147PMID : 36242688
• Kataoka F, Miura S, Kume K, Kikuta K, Hamada S, Takikawa T, Matsumoto R, Ikeda M, Sano T, Sasaki A, Masamune AA case of occult pancreaticobiliary reflux due to endoscopically confirmed relaxation of the Oddi sphincter.DEN open ( 2023) 3(1): e161PMID : 36189169
• Ohneda K, Hamanaka Y, Kawame H, Fuse N, Nagami F, Suzuki Y, Yamaguchi-Kabata Y, Shimada M, Masamune A, Aoki Y, Ishida T, Yamamoto MReturning individual genomic results to population-based cohort study participants with BRCA1/2 pathogenic variants.Breast Cancer ( 2023) 30(1): 110-120PMID : 36161580

2022年(25件)

• Masamune A, Hamada S, Kikuta KDiagnosis of Disseminated Intravascular Coagulation in Acute Pancreatitis Is Still a Challenge.Pancreas ( 2022) 51(10): e116-e117PMID : 37099793
• Sato Y, Tsuyusaki M, Takahashi-Iwanaga H, Fujisawa R, Masamune A, Hamada S, Matsumoto R, Tanaka Y, Kakuta Y, Yamaguchi-Kabata Y, Furuse T, Wakana S, Shimura T, Kobayashi R, Shinoda Y, Goitsuka R, Maezawa S, Sadakata T, Sano Y, Furuichi TLoss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice.Front Mol Biosci ( 2022) 9 1040237PMID : 36419930
• Harigai A, Kume K, Takahashi N, Omata S, Umezawa R, Jingu K, Masamune AFavorable response after radiation therapy for intraductal papillary mucinous neoplasms manifesting as acute recurrent pancreatitis: A case report.World J Clin Cases ( 2022) 10(30): 11116-11121PMID : 36338229
• Hayashi H, Miura S, Fujishima F, Kuniyoshi S, Kume K, Kikuta K, Hamada S, Takikawa T, Matsumoto R, Ikeda M, Sano T, Kataoka F, Sasaki A, Sakano M, Masamune AUtility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis.Diagnostics (Basel) ( 2022) 12(10):PMID : 36292153
• Takikawa T, Hamada S, Matsumoto R, Tanaka Y, Kataoka F, Sasaki A, Masamune ASenescent Human Pancreatic Stellate Cells Secrete CXCR2 Agonist CXCLs to Promote Proliferation and Migration of Human Pancreatic Cancer AsPC-1 and MIAPaCa-2 Cell Lines.Int J Mol Sci ( 2022) 23(16):PMID : 36012531
• Shimizu K, Ito T, Irisawa A, Ohtsuka T, Ohara H, Kanno A, Kida M, Sakagami J, Sata N, Takeyama Y, Tahara J, Hirota M, Fujimori N, Masamune A, Mochida S, Enomoto N, Shimosegawa T, Koike KEvidence-based clinical practice guidelines for chronic pancreatitis 2021.J Gastroenterol ( 2022) 57(10): 709-724PMID : 35994093
• Kubota K, Oguchi T, Fujimori N, Yamada K, Naitoh I, Okabe Y, Iwasaki E, Masamune A, Ikeura T, Kamisawa T, Inoue D, Kumagi T, Ogura T, Kodama Y, Katanuma A, Hirano K, Inui K, Isayama H, Sakagami J, Nishino T, Kanno A, Kurita Y, Okazaki K, Nakamura SSteroid therapy has an acceptable role as the initial treatment in autoimmune pancreatitis patients with pancreatic cyst formation: based on a Japanese nationwide study.J Hepatobiliary Pancreat Sci ( 2022) PMID : 35950952
• Chong YP, Peter EP, Lee FJM, Chan CM, Chai S, Ling LPC, Tan EL, Ng SH, Masamune A, Ghafar SAA, Ismail N, Ho KLConditioned media of pancreatic cancer cells and pancreatic stellate cells induce myeloid-derived suppressor cells differentiation and lymphocytes suppression.Sci Rep ( 2022) 12(1): 12315PMID : 35853996
• Ikeda M, Miura S, Kume K, Kikuta K, Hamada S, Takikawa T, Nakagawa K, Unno M, Furukawa T, Masamune APancreatic mixed acinar-neuroendocrine carcinoma in a patient with a germline BRCA2 mutation: a case report.Clin J Gastroenterol ( 2022) PMID : 35819745
• Kabashima A, Matsuo Y, Ito S, Akiyama Y, Ishii T, Shimada S, Masamune A, Tanabe M, Tanaka ScGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer.Sci Rep ( 2022) 12(1): 10466PMID : 35773436
• Hirano N, Iseki M, Morikawa T, Umino Y, Aoki S, Inoue K, Nakayama S, Miura T, Masuda K, Ishida M, Ohtsuka H, Mizuma M, Nakagawa K, Kume K, Masamune A, Kamei T, Unno MPancreaticoduodenectomy for pancreatic head cancer with cavernous transformation of the portal vein: a case report.Surg Case Rep ( 2022) 8(1): 127PMID : 35771287
• Rygiel AM, Unger LS, Sörgel FL, Masson E, Matsumoto R, Ewers M, Chen JM, Bugert P, Buscail L, Gambin T, Oracz G, Winiewska-Szajewska M, Mianowska A, Poznanski J, Kosińska J, Stawinski P, Płoski R, Koziel D, Gluszek S, Laumen H, Lindgren F, Löhr JM, Orekhova A, Rebours V, Rosendahl J, Párniczky A, Hegyi P, Sasaki A, Kataoka F, Tanaka Y, Hamada S, Sahin-Tóth M, Hegyi E, Férec C, Masamune A, Witt HVariants in the pancreatic CUB and zona pellucida-like domains 1 (CUZD1) gene in early-onset chronic pancreatitis - A possible new susceptibility gene.Pancreatology ( 2022) PMID : 35589511
• Ikeda M, Hamada S, Kikuta K, Takikawa T, Yoshida N, Matsumoto R, Tanaka Y, Kataoka F, Sasaki A, Tarasawa K, Fujimori K, Fushimi K, Masamune AAcute Pancreatitis in Japan: Comparison of Before and After Revision of the Clinical Guidelines.Pancreas ( 2022) 51(3): 261-268PMID : 35584384
• Kitano M, Yoshida M, Ashida R, Kita E, Katanuma A, Itoi T, Mikata R, Nishikawa K, Matsubayashi H, Takayama Y, Kato H, Takenaka M, Ueki T, Kawashima Y, Nakai Y, Hashimoto S, Shigekawa M, Nebiki H, Tsumura H, Okabe Y, Ryozawa S, Harada Y, Mitoro A, Sasaki T, Yasuda H, Miura N, Ikemoto T, Ozawa E, Shioji K, Yamaguchi A, Okuzono T, Moriyama I, Hisai H, Fujita K, Goto T, Shirahata N, Iwata Y, Okabe Y, Hara K, Hashimoto Y, Kuwatani M, Isayama H, Fujimori N, Masamune A, Hatamaru K, Shimokawa T, Okazaki K, Takeyama Y, Yamaue HNeedle tract seeding after endoscopic ultrasound-guided tissue acquisition of pancreatic tumors: A nationwide survey in Japan.Dig Endosc ( 2022) PMID : 35502924
• Ren H, Mori N, Sato S, Mugikura S, Masamune A, Takase KAmerican College of Rheumatology and the European League Against Rheumatism classification criteria for IgG4-related disease: an update for radiologists.Jpn J Radiol ( 2022) PMID : 35474439
• Kubota K, Kamisawa T, Nakazawa T, Tanaka A, Naitoh I, Takikawa H, Unno M, Kawa S, Masamune A, Nakamura S, Okazaki KSteroid therapy still plays a crucial role and could serve as a bridge to the next promising treatments in patients with IgG4-related sclerosing cholangitis: Results of a Japanese Nationwide Study.J Hepatobiliary Pancreat Sci ( 2022) PMID : 35460190
• Iida T, Mizutani Y, Esaki N, Ponik SM, Burkel BM, Weng L, Kuwata K, Masamune A, Ishihara S, Haga H, Kataoka K, Mii S, Shiraki Y, Ishikawa T, Ohno E, Kawashima H, Hirooka Y, Fujishiro M, Takahashi M, Enomoto APharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics.Oncogene ( 2022) PMID : 35414659
• Takada T, Isaji S, Mayumi T, Yoshida M, Takeyama Y, Itoi T, Sano K, Iizawa Y, Masamune A, Hirota M, Okamoto K, Inoue D, Kitamura N, Mori Y, Mukai S, Kiriyama S, Shirai K, Tsuchiya A, Higuchi R, Hirashita TJPN clinical practice guidelines 2021 with easy-to-understand explanations for the management of acute pancreatitis.J Hepatobiliary Pancreat Sci ( 2022) PMID : 35388634
• Hamada S, Matsumoto R, Masamune APancreatic Stellate Cells and Metabolic Alteration: Physiology and Pathophysiology.Front Physiol ( 2022) 13 865105PMID : 35370770
• Takikawa T, Kikuta K, Hamada S, Kume K, Miura S, Yoshida N, Tanaka Y, Matsumoto R, Ikeda M, Kataoka F, Sasaki A, Nakagawa K, Unno M, Masamune AClinical features and prognostic impact of asymptomatic pancreatic cancer.Sci Rep ( 2022) 12(1): 4262PMID : 35277545
• Takikawa T, Kikuta K, Hamada S, Kume K, Miura S, Yoshida N, Tanaka Y, Matsumoto R, Ikeda M, Kataoka F, Sasaki A, Hayashi H, Hatta W, Ogata Y, Nakagawa K, Unno M, Masamune AA New Preoperative Scoring System for Predicting Aggressiveness of Non-Functioning Pancreatic Neuroendocrine Neoplasms.Diagnostics (Basel) ( 2022) 12(2):PMID : 35204488
• Okazaki K, Kawa S, Kamisawa T, Ikeura T, Itoi T, Ito T, Inui K, Irisawa A, Uchida K, Ohara H, Kubota K, Kodama Y, Shimizu K, Tonozuka R, Nakazawa T, Nishino T, Notohara K, Fujinaga Y, Masamune A, Yamamoto H, Watanabe T, Nishiyama T, Kawano M, Shiratori K, Shimosegawa T, Takeyama YAmendment of the Japanese consensus guidelines for autoimmune pancreatitis, 2020.J Gastroenterol ( 2022) PMID : 35192048
• Oshima Y, Sano M, Kajiwara I, Ichimaru Y, Itaya T, Kuramochi T, Hayashi E, Kim J, Kitajima O, Masugi Y, Masamune A, Ijichi H, Ishii Y, Suzuki TMidazolam exhibits antitumour and anti-inflammatory effects in a mouse model of pancreatic ductal adenocarcinoma.Br J Anaesth ( 2022) PMID : 35120712
• Hamada S, Matsumoto R, Masamune AHIF-1 and NRF2; Key Molecules for Malignant Phenotypes of Pancreatic Cancer.Cancers (Basel) ( 2022) 14(2):PMID : 35053572
• Hamada S, Masson E, Chen JM, Sakaguchi R, Rebours V, Buscail L, Matsumoto R, Tanaka Y, Kikuta K, Kataoka F, Sasaki A, Le Rhun M, Audin H, Lachaux A, Caumont B, Lorenzo D, Billiemaz K, Besnard R, Koch S, Lamireau T, De Koninck X, Génin E, Cooper DN, Mori Y, Masamune A, Férec CFunctionally deficient TRPV6 variants contribute to hereditary and familial chronic pancreatitis.Hum Mutat ( 2022) 43(2): 228-239PMID : 34923708

2021年(13件)

• Miura S, Takikawa T, Kikuta K, Hamada S, Kume K, Yoshida N, Tanaka Y, Matsumoto R, Ikeda M, Kataoka F, Sasaki A, Hatta W, Inoue J, Masamune AFocal Parenchymal Atrophy of the Pancreas Is Frequently Observed on Pre-Diagnostic Computed Tomography in Patients with Pancreatic Cancer: A Case-Control Study.Diagnostics (Basel) ( 2021) 11(9):PMID : 34574034
• Masaki Y, Nakase H, Tsuji Y, Nojima M, Shimizu K, Mizuno N, Ikeura T, Uchida K, Ido A, Kodama Y, Seno H, Okazaki K, Nakamura S, Masamune AThe clinical efficacy of azathioprine as maintenance treatment for autoimmune pancreatitis: a systematic review and meta-analysis.J Gastroenterol ( 2021) 56(10): 869-880PMID : 34426870
• Tanaka Y, Hamada S, Matsumoto R, Taguchi K, Yamamoto M, Masamune ANrf2 expression in pancreatic stellate cells promotes progression of cancer.Am J Physiol Gastrointest Liver Physiol ( 2021) 321(4): G378-G388PMID : 34405729
• Matsumoto R, Hamada S, Tanaka Y, Taguchi K, Yamamoto M, Masamune ANuclear Factor Erythroid 2-Related Factor 2 Depletion Sensitizes Pancreatic Cancer Cells to Gemcitabine via Aldehyde Dehydrogenase 3a1 Repression.J Pharmacol Exp Ther ( 2021) 379(1): 33-40PMID : 34321315
• Ikeda M, Miura S, Hamada S, Sano T, Matsumoto R, Tanaka Y, Hongo S, Yoshida N, Takikawa T, Kikuta K, Kume K, Hata T, Unno M, Omori Y, Furukawa T, Masamune AAcinar Cell Carcinoma with Morphological Change in One Month.Intern Med ( 2021) 60(17): 2799-2806PMID : 33746172
• Hamada S, Matsumoto R, Tanaka Y, Taguchi K, Yamamoto M, Masamune ANrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition.Int J Mol Sci ( 2021) 22(4):PMID : 33672789
• Naitoh I, Kamisawa T, Tanaka A, Nakazawa T, Kubota K, Takikawa H, Unno M, Masamune A, Kawa S, Nakamura S, Okazaki KClinical characteristics of immunoglobulin IgG4-related sclerosing cholangitis: Comparison of cases with and without autoimmune pancreatitis in a large cohort.Dig Liver Dis ( 2021) 53(10): 1308-1314PMID : 33664004
• Ota S, Tanke G, Asai S, Ito R, Hara K, Takada Y, Adachi K, Shimada Y, Hayashi M, Itani T, Ishihara M, Masamune AAn Autopsy Case of Anaplastic Carcinoma of the Pancreas in a 39-Year-Old Woman that Developed from Hereditary Pancreatitis.Am J Case Rep ( 2021) 22 e928993PMID : 33587725
• Nakazawa T, Kamisawa T, Okazaki K, Kawa S, Tazuma S, Nishino T, Inoue D, Naitoh I, Watanabe T, Notohara K, Kubota K, Ohara H, Tanaka A, Takikawa H, Masamune A, Unno TClinical diagnostic criteria for IgG4-related sclerosing cholangitis 2020 (Revision of the clinical diagnostic criteria for IgG4-related sclerosing cholangitis 2012).J Hepatobiliary Pancreat Sci ( 2021) PMID : 33586343
• Masamune A, Hamada S, Kikuta KImplementation of Pancreatitis Bundles Is Associated With Reduced Mortality in Patients With Severe Acute Pancreatitis in Japan.Pancreas ( 2021) 50(2): e24-e25PMID : 33565810
• Miura S, Hamada S, Kume K, Kikuta K, Takikawa T, Yoshida N, Masamune AA case of double common bile duct visually detected only by cholangioscope.Endoscopy ( 2021) 53(12): E457-E458PMID : 33540439
• Tanaka Y, Takikawa T, Kume K, Kikuta K, Hamada S, Miura S, Yoshida N, Hongo S, Matsumoto R, Sano T, Ikeda M, Unno M, Masamune AIgG4-related Diaphragmatic Inflammatory Pseudotumor.Intern Med ( 2021) 60(13): 2067-2074PMID : 33518577
• Iseki M, Mizuma M, Aoki Y, Aoki S, Hata T, Takadate T, Kawaguchi K, Masuda K, Ishida M, Ohtsuka H, Nakagawa K, Hayashi H, Morikawa T, Kamei T, Kume K, Kanno A, Masamune A, Omori Y, Ono Y, Mizukami Y, Furukawa T, Unno MIntracholecystic papillary neoplasm arising in the cystic duct and extending into common bile duct: a case report.Clin J Gastroenterol ( 2021) 14(2): 668-677PMID : 33387260

2020年(16件)

• Takikawa T, Kikuta K, Kume K, Hamada S, Miura S, Yoshida N, Hongo S, Tanaka Y, Matsumoto R, Sano T, Ikeda M, Iseki M, Unno M, Masamune ANew-Onset or Exacerbation of Diabetes Mellitus Is a Clue to the Early Diagnosis of Pancreatic Cancer.Tohoku J Exp Med ( 2020) 252(4): 353-364PMID : 33342915
• Kanno A, Yasuda I, Irisawa A, Hara K, Ashida R, Iwashita T, Takenaka M, Katanuma A, Takikawa T, Kubota K, Kato H, Nakai Y, Ryozawa S, Kitano M, Isayama H, Kamada H, Okabe Y, Hanada K, Ohtsubo K, Doi S, Hisai H, Shibukawa G, Imazu H, Masamune AAdverse events of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Histologic Diagnosis in Japanese Tertiary Centers: A Multicenter Retrospective Study.Dig Endosc ( 2020) PMID : 33284491
• Ren H, Mori N, Hamada S, Takasawa C, Mugikura S, Masamune A, Takase KEffective apparent diffusion coefficient parameters for differentiation between mass-forming autoimmune pancreatitis and pancreatic ductal adenocarcinoma.Abdom Radiol (NY) ( 2020) PMID : 33037891
• Miura S, Kume K, Kikuta K, Hamada S, Takikawa T, Yoshida N, Hongo S, Tanaka Y, Matsumoto R, Sano T, Ikeda M, Furukawa T, Iseki M, Unno M, Masamune AFocal Parenchymal Atrophy and Fat Replacement Are Clues for Early Diagnosis of Pancreatic Cancer with Abnormalities of the Main Pancreatic Duct.Tohoku J Exp Med ( 2020) 252(1): 63-71PMID : 32879148
• Sano T, Miura S, Masamune AEndoscopic retrieval device for proximally migrated pancreatic and biliary stent: Wire-guided spiral basket catheter.Dig Endosc ( 2020) PMID : 32861225
• Kajiwara I, Sano M, Ichimaru Y, Oshima Y, Kitajima O, Hao H, Masamune A, Kim J, Ishii Y, Ijichi H, Suzuki TDuloxetine improves cancer-associated pain in a mouse model of pancreatic cancer via stimulation of noradrenaline pathway and its antitumor effects.Pain ( 2020) PMID : 32694385
• Masamune A, Kikuta K, Kume K, Hamada S, Tsuji I, Takeyama Y, Shimosegawa T, Okazaki KNationwide epidemiological survey of chronic pancreatitis in Japan: introduction and validation of the new Japanese diagnostic criteria 2019.J Gastroenterol ( 2020) PMID : 32676800
• Mel Wilcox C, Gress T, Boermeester M, Masamune A, Lévy P, Itoi T, Varadarajulu S, Irisawa A, Levy M, Kitano M, Garg P, Isaji S, Shimosegawa T, Sheel ARG, Whitcomb DC, Neoptolemos JPInternational consensus guidelines on the role of diagnostic endoscopic ultrasound in the management of chronic pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with the International Association of Pancreatology, the American Pancreatic Association, the Japan Pancreas Society, and European Pancreatic Club.Pancreatology ( 2020) PMID : 32631791
• Satoi S, Yamamoto T, Uchida K, Fujii T, Kin T, Hirano S, Hanada K, Itoi T, Murakami Y, Igarashi H, Eguchi H, Kuroki T, Shimizu Y, Tani M, Tanno S, Tsuji Y, Hirooka Y, Masamune A, Shimokawa T, Yamaue H, Okazaki KOptimal Treatment for Octogenarians With Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma: A Multicenter Retrospective Study.Pancreas ( 2020) 49(6): 837-844PMID : 32590619
• Masamune A, Kikuta K, Hamada S, Tsuji I, Takeyama Y, Shimosegawa T, Okazaki KClinical practice of acute pancreatitis in Japan: An analysis of nationwide epidemiological survey in 2016.Pancreatology ( 2020) PMID : 32409278
• Tanaka HY, Kurihara T, Nakazawa T, Matsusaki M, Masamune A, Kano MRHeterotypic 3D pancreatic cancer model with tunable proportion of fibrotic elements.Biomaterials ( 2020) 251 120077PMID : 32388166
• Hegyi P, Párniczky A, Lerch MM, Sheel ARG, Rebours V, Forsmark CE, Del Chiaro M, Rosendahl J, de-Madaria E, Szücs Á, Takaori K, Yadav D, Gheorghe C, Rakonczay Z Jr, Molero X, Inui K, Masamune A, Fernandez-Del Castillo C, Shimosegawa T, Neoptolemos JP, Whitcomb DC, Sahin-Tóth MInternational Consensus Guidelines for Risk Factors in Chronic Pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with the International Association of Pancreatology, the American Pancreatic Association, the Japan Pancreas Society, and European Pancreatic Club.Pancreatology ( 2020) PMID : 32376198
• Hata T, Mizuma M, Motoi F, Ishida M, Morikawa T, Nakagawa K, Hayashi H, Kanno A, Masamune A, Kamei T, Naitoh T, Furukawa T, Unno MAn integrated analysis of host- and tumor-derived markers for predicting high-grade dysplasia and associated invasive carcinoma of intraductal papillary mucinous neoplasms of the pancreas.Surg Today ( 2020) PMID : 32124086
• Hashimoto D, Mizuma M, Kumamaru H, Miyata H, Chikamoto A, Igarashi H, Itoi T, Egawa S, Kodama Y, Satoi S, Hamada S, Mizumoto K, Yamaue H, Yamamoto M, Kakeji Y, Seto Y, Baba H, Unno M, Shimosegawa T, Okazaki KRisk model for severe postoperative complications after total pancreatectomy based on a nationwide clinical database.Br J Surg ( 2020) PMID : 32003458
• Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune AKeap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma.Am J Physiol Gastrointest Liver Physiol ( 2020) PMID : 31961719
• Masamune A, Kotani H, Sörgel FL, Chen JM, Hamada S, Sakaguchi R, Masson E, Nakano E, Kakuta Y, Niihori T, Funayama R, Shirota M, Hirano T, Kawamoto T, Hosokoshi A, Kume K, Unger L, Ewers M, Laumen H, Bugert P, Mori MX, Tsvilovskyy V, Weißgerber P, Kriebs U, Fecher-Trost C, Freichel M, Diakopoulos KN, Berninger A, Lesina M, Ishii K, Itoi T, Ikeura T, Okazaki K, Kaune T, Rosendahl J, Nagasaki M, Uezono Y, Algül H, Nakayama K, Matsubara Y, Aoki Y, Férec C, Mori Y, Witt H, Shimosegawa TVariants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis.Gastroenterology ( 2020) 158(6): 1626-1641.e8PMID : 31930989

2019年(16件)

• Matsumoto R, Miura S, Kanno A, Ikeda M, Sano T, Tanaka Y, Nabeshima T, Hongou S, Takikawa T, Hamada S, Kume K, Kikuta K, Masamune AA Case of IgG4-related Sclerosing Cholangitis Mimicking Cholangiocarcinoma Diagnosed by Endoscopic Ultrasound-guided Fine-needle Aspiration.Intern Med ( 2019) PMID : 31875638
• Masamune A, Kikuta K, Hamada S, Tsuji I, Takeyama Y, Shimosegawa T, Okazaki KNationwide epidemiological survey of autoimmune pancreatitis in Japan in 2016.J Gastroenterol ( 2019) PMID : 31872350
• Kempeneers MA, Issa Y, Ali UA, Baron RD, Besselink MG, Büchler M, Erkan M, Fernandez-Del Castillo C, Isaji S, Izbicki J, Kleeff J, Laukkarinen J, Sheel ARG, Shimosegawa T, Whitcomb DC, Windsor J, Miao Y, Neoptolemos J, Boermeester MAInternational consensus guidelines for surgery and the timing of intervention in chronic pancreatitis.Pancreatology ( 2019) PMID : 31870802
• Hirota M, Shimosegawa T, Kitamura K, Takeda K, Takeyama Y, Mayumi T, Ito T, Takenaka M, Iwasaki E, Sawano H, Ishida E, Miura S, Masamune A, Nakai Y, Mitoro A, Maguchi H, Kimura K, Sanuki T, Ito T, Haradome H, Kozaka K, Gabata T, Kataoka K, Hirota M, Isaji S, Nakamura R, Yamagiwa K, Kayaba C, Ikeda KContinuous regional arterial infusion versus intravenous administration of the protease inhibitor nafamostat mesilate for predicted severe acute pancreatitis: a multicenter, randomized, open-label, phase 2 trial.J Gastroenterol ( 2019) PMID : 31758329
• Tsuchida H, Fujii T, Mizuma M, Satoi S, Igarashi H, Eguchi H, Kuroki T, Shimizu Y, Tani M, Tanno S, Tsuji Y, Hirooka Y, Masamune A, Mizumoto K, Itoi T, Egawa S, Kodama Y, Hamada S, Unno M, Yamaue H, Okazaki KPrognostic importance of peritoneal washing cytology in patients with otherwise resectable pancreatic ductal adenocarcinoma who underwent pancreatectomy: A nationwide, cancer registry-based study from the Japan Pancreas Society.Surgery ( 2019) PMID : 31445763
• Mizutani Y, Kobayashi H, Iida T, Asai N, Masamune A, Hara A, Esaki N, Ushida K, Mii S, Shiraki Y, Ando K, Weng L, Ishihara S, Ponik SM, Conklin MW, Haga H, Nagasaka A, Miyata T, Matsuyama M, Kobayashi T, Fujii T, Yamada S, Yamaguchi J, Wang T, Woods SL, Worthley D, Shimamura T, Fujishiro M, Hirooka Y, Takahashi M, Enomoto AMeflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis.Cancer Res ( 2019) PMID : 31439548
• Yoshimachi S, Ohtsuka H, Aoki T, Miura T, Ariake K, Masuda K, Ishida M, Mizuma M, Hayashi H, Nakagawa K, Morikawa T, Motoi F, Kanno A, Masamune A, Fujishima F, Sasano H, Kamei T, Naitoh T, Unno MMixed adenoneuroendocrine carcinoma of the ampulla of Vater: a case report and literature review.Clin J Gastroenterol ( 2019) PMID : 31342462
• Masamune A, Nabeshima T, Kikuta K, Hamada S, Nakano E, Kume K, Kanno A, Sato A, Tachibana Y, Inatomi O, Yamamoto S, Ikeura T, Futagami S, Taguchi M, Hanada K, Shimizu K, Kageoka M, Saito T, Eguchi T, Kubota K, Takenaka M, Mima A, Irisawa A, Ito T, Andoh A, Inui K, Takeyama Y, Yamaue H, Okazaki K, Shimosegawa TProspective study of early chronic pancreatitis diagnosed based on the Japanese diagnostic criteria.J Gastroenterol ( 2019) PMID : 31270692
• Iida-Norita R, Kawamura M, Suzuki Y, Hamada S, Masamune A, Furukawa T, Sato YVasohibin-2 plays an essential role in metastasis of pancreatic ductal adenocarcinoma.Cancer Sci ( 2019) PMID : 31074083
• Miura S, Kanno A, Fukase K, Tanaka Y, Matsumoto R, Nabeshima T, Hongou S, Takikawa T, Hamada S, Kume K, Kikuta K, Nakagawa K, Unno M, Masamune APreoperative biliary drainage of the hepatic lobe to be resected does not affect liver hypertrophy after percutaneous transhepatic portal vein embolization.Surg Endosc ( 2019) PMID : 31062157
• Kanno A, Masamune A[Diagnosis of autoimmune pancreatitis -imaging and histological diagnosis using EUS-FNA].Nihon Shokakibyo Gakkai Zasshi ( 2019) 116(4): 286-295PMID : 30971665
• Lasher D, Szabó A, Masamune A, Chen JM, Xiao X, Whitcomb DC, Barmada MM, Ewers M, Ruffert C, Paliwal S, Issarapu P, Bhaskar S, Mani KR, Chandak GR, Laumen H, Masson E, Kume K, Hamada S, Nakano E, Seltsam K, Bugert P, Müller T, Groneberg DA, Shimosegawa T, Rosendahl J, Férec C, Lowe ME, Witt H, Sahin-Tóth MProtease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.Am J Gastroenterol ( 2019) PMID : 30789418
• Kanno A, Masamune A, Hanada K, Kikuyama M, Kitano MAdvances in Early Detection of Pancreatic Cancer.Diagnostics (Basel) ( 2019) 9(1):PMID : 30764550
• Yasuda H, Kataoka K, Takeyama Y, Takeda K, Ito T, Mayumi T, Isaji S, Mine T, Kitagawa M, Kiriyama S, Sakagami J, Masamune A, Inui K, Hirano K, Akashi R, Yokoe M, Sogame Y, Okazaki K, Morioka C, Kihara Y, Kawa S, Tanaka M, Andoh A, Kimura W, Nishimori I, Furuse J, Yokota I, Shimosegawa TUsefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis: A multicenter study in Japan.World J Gastroenterol ( 2019) 25(1): 107-117PMID : 30643362
• Hata T, Mizuma M, Motoi F, Ishida M, Morikawa T, Takadate T, Nakagawa K, Hayashi H, Kanno A, Masamune A, Kamei T, Furukawa T, Naitoh T, Unno MDiagnostic and Prognostic Impact of Neutrophil-to-Lymphocyte Ratio for Intraductal Papillary Mucinous Neoplasms of the Pancreas With High-Grade Dysplasia and Associated Invasive Carcinoma.Pancreas ( 2019) 48(1): 99-106PMID : 30540681
• Ito T, Kawa S, Matsumoto A, Kubota K, Kamisawa T, Okazaki K, Hirano K, Hirooka Y, Uchida K, Masuda A, Ohara H, Shimizu K, Arakura N, Masamune A, Kanno A, Sakagami J, Itoi T, Ito T, Ueki T, Nishino T, Inui K, Mizuno N, Yoshida H, Sugiyama M, Iwasaki E, Irisawa A, Shimosegawa T, Chiba TRisk Factors for Pancreatic Stone Formation in Type 1 Autoimmune Pancreatitis: A Long-term Japanese Multicenter Analysis of 624 Patients.Pancreas ( 2019) 48(1): 49-54PMID : 30540679

2018年(11件)

• Tanaka HY, Kitahara K, Sasaki N, Nakao N, Sato K, Narita H, Shimoda H, Matsusaki M, Nishihara H, Masamune A, Kano MRPancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness.Biomaterials ( 2018) 192 355-367PMID : 30476717
• Asama H, Suzuki R, Hikichi T, Takagi T, Masamune A, Ohira HMicroRNA let-7d targets thrombospondin-1 and inhibits the activation of human pancreatic stellate cells.Pancreatology ( 2018) PMID : 30393009
• Ishii N, Araki K, Yokobori T, Hagiwara K, Dorgormaa G, Yamanaka T, Handa T, Tsukagoshi M, Igarashi T, Watanabe A, Kubo N, Harimoto N, Masamune A, Umezawa K, Kuwano H, Shirabe KConophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts.Cancer Sci ( 2018) PMID : 30353606
• Yoshida N, Kanno A, Masamune A, Nabeshima T, Hongo S, Miura S, Takikawa T, Hamada S, Kikuta K, Kume K, Ueno M, Shimosegawa TPancreatic Acinar Cell Carcinoma with Multiple Liver Metastases Effectively Treated by S-1 Chemotherapy.Intern Med ( 2018) PMID : 30101903
• Whitcomb DC, Shimosegawa T, Chari ST, Forsmark CE, Frulloni L, Garg P, Hegyi P, Hirooka Y, Irisawa A, Ishikawa T, Isaji S, Lerch MM, Levy P, Masamune A, Wilcox CM, Windsor J, Yadav D, Sheel A, Neoptolemos JPInternational consensus statements on early chronic Pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with The International Association of Pancreatology, American Pancreatic Association, Japan Pancreas Society, PancreasFest Working Group and European Pancreatic Club.Pancreatology ( 2018) PMID : 29793839
• Masamune A, Hamada S, Yoshida N, Nabeshima T, Shimosegawa TPyruvate Kinase Isozyme M2 Plays a Critical Role in the Interactions Between Pancreatic Stellate Cells and Cancer Cells.Dig Dis Sci ( 2018) PMID : 29619774
• Hamada S, Masamune AElucidating the link between collagen and pancreatic cancer: what's next?Expert Rev Gastroenterol Hepatol ( 2018) PMID : 29495889
• Suzuki R, Asama H, Waragai Y, Takagi T, Hikichi T, Sugimoto M, Konno N, Watanabe K, Nakamura J, Kikuchi H, Sato Y, Marubashi S, Masamune A, Ohira HFibrosis-related miRNAs as serum biomarkers for pancreatic ductal adenocarcinoma.Oncotarget ( 2018) 9(4): 4451-4460PMID : 29435115
• Hamada S, Masamune A, Nabeshima T, Shimosegawa TDifferences in Gut Microbiota Profiles between Autoimmune Pancreatitis and Chronic Pancreatitis.Tohoku J Exp Med ( 2018) 244(2): 113-117PMID : 29434076
• Kubota K, Kamisawa T, Hirano K, Hirooka Y, Uchida K, Ikeura T, Shiomi H, Ohara H, Shimizu K, Arakura N, Kanno A, Sakagami J, Itoi T, Ito T, Ueki T, Nishino T, Inui K, Mizuno N, Yoshida H, Sugiyama M, Iwasaki E, Irisawa A, Okazaki K, Kawa S, Shimosegawa T, Takeyama Y, Chiba TClinical course of type 1 autoimmune pancreatitis patients without steroid treatment: a Japanese multicenter study of 97 patients.J Hepatobiliary Pancreat Sci ( 2018) PMID : 29430861
• Matsuoka K, Kobayashi T, Ueno F, Matsui T, Hirai F, Inoue N, Kato J, Kobayashi K, Kobayashi K, Koganei K, Kunisaki R, Motoya S, Nagahori M, Nakase H, Omata F, Saruta M, Watanabe T, Tanaka T, Kanai T, Noguchi Y, Takahashi KI, Watanabe K, Hibi T, Suzuki Y, Watanabe M, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for inflammatory bowel disease.J Gastroenterol ( 2018) PMID : 29429045

2017年(27件)

• Hamada S, Taguchi K, Masamune A, Yamamoto M, Shimosegawa TNrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis.Carcinogenesis ( 2017) 38(6): 661-670PMID : 29240881
• Hamada S, Masamune A, Kikuta K, Shimosegawa TSeverity assessment of acute pancreatitis using four prognostic factors - a nationwide multicenter study of 3682 cases in Japan.United European Gastroenterol J ( 2017) 5(8): 1136-1137PMID : 29238593
• Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa TMulticenter study of early pancreatic cancer in Japan.Pancreatology ( 2017) PMID : 29170051
• Nabeshima T, Kanno A, Masamune A, Hayashi H, Hongo S, Yoshida N, Nakano E, Miura S, Hamada S, Kikuta K, Kume K, Hirota M, Unno M, Shimosegawa TSuccessful Endoscopic Treatment of Severe Pancreaticojejunostomy Strictures by Puncturing the Anastomotic Site with an EUS-guided Guidewire: A Report of Two Cases.Intern Med ( 2017) PMID : 29151507
• Masamune A, Yoshida N, Hamada S, Takikawa T, Nabeshima T, Shimosegawa TExosomes derived from pancreatic cancer cells induce activation and profibrogenic activities in pancreatic stellate cells.Biochem Biophys Res Commun ( 2017) PMID : 29111329
• Hata T, Kawamoto K, Eguchi H, Kamada Y, Takamatsu S, Maekawa T, Nagaoka S, Yamada D, Iwagami Y, Asaoka T, Noda T, Wada H, Gotoh K, Masamune A, Miyoshi E, Mori M, Doki YFatty Acid-Mediated Stromal Reprogramming of Pancreatic Stellate Cells Induces Inflammation and Fibrosis That Fuels Pancreatic Cancer.Pancreas ( 2017) PMID : 28991878
• Hamada S, Shimosegawa T, Taguchi K, Nabeshima T, Yamamoto M, Masamune ASimultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.Am J Physiol Gastrointest Liver Physiol ( 2017) ajpgi.00228.2017PMID : 28971839
• Kleeff J, Whitcomb DC, Shimosegawa T, Esposito I, Lerch MM, Gress T, Mayerle J, Drewes AM, Rebours V, Akisik F, Muñoz JED, Neoptolemos JPChronic pancreatitis.Nat Rev Dis Primers ( 2017) 3 17060PMID : 28880010
• Masamune A, Kikuta K, Hamada S, Nakano E, Kume K, Inui A, Shimizu T, Takeyama Y, Nio M, Shimosegawa TNationwide survey of hereditary pancreatitis in Japan.J Gastroenterol ( 2017) PMID : 28861620
• Issa Y, van Santvoort HC, Fockens P, Besselink MG, Bollen TL, Bruno MJ, Boermeester MADiagnosis and treatment in chronic pancreatitis: an international survey and case vignette study.HPB (Oxford) ( 2017) PMID : 28821411
• Basturk O, Berger MF, Yamaguchi H, Adsay V, Askan G, Bhanot UK, Zehir A, Carneiro F, Hong SM, Zamboni G, Dikoglu E, Jobanputra V, Wrzeszczynski KO, Balci S, Allen P, Ikari N, Takeuchi S, Akagawa H, Kanno A, Shimosegawa T, Morikawa T, Motoi F, Unno M, Higuchi R, Yamamoto M, Shimizu K, Furukawa T, Klimstra DSPancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma.Mod Pathol ( 2017) PMID : 28776573
• Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth MGenome-wide association study identifies inversion in the <i>CTRB1-CTRB2</i> locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.Gut ( 2017) PMID : 28754779
• Drewes AM, Bouwense SAW, Campbell CM, Ceyhan GO, Delhaye M, Demir IE, Garg PK, van Goor H, Halloran C, Isaji S, Neoptolemos JP, Olesen SS, Palermo T, Pasricha PJ, Sheel A, Shimosegawa T, Szigethy E, Whitcomb DC, Yadav DGuidelines for the understanding and management of pain in chronic pancreatitis.Pancreatology ( 2017) PMID : 28734722
• Mine T, Morizane T, Kawaguchi Y, Akashi R, Hanada K, Ito T, Kanno A, Kida M, Miyagawa H, Yamaguchi T, Mayumi T, Takeyama Y, Shimosegawa TClinical practice guideline for post-ERCP pancreatitis.J Gastroenterol ( 2017) PMID : 28653082
• Van Audenaerde JRM, De Waele J, Marcq E, Van Loenhout J, Lion E, Van den Bergh JMJ, Jesenofsky R, Masamune A, Roeyen G, Pauwels P, Lardon F, Peeters M, Smits ELJInterleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells.Oncotarget ( 2017) PMID : 28615524
• Hamada S, Masamune A, Shimosegawa TTransition of early-phase treatment for acute pancreatitis: An analysis of nationwide epidemiological survey.World J Gastroenterol ( 2017) 23(16): 2826-2831PMID : 28522901
• Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe TA novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β₁ pathways.Sci Rep ( 2017) 7(1): 1884PMID : 28507324
• Yamaguchi K, Okusaka T, Shimizu K, Furuse J, Ito Y, Hanada K, Shimosegawa T, Okazaki KClinical Practice Guidelines for Pancreatic Cancer 2016 From the Japan Pancreas Society: A Synopsis.Pancreas ( 2017) 46(5): 595-604PMID : 28426492
• Go VL, Shimosegawa T, Saluja AK, Fuchs AR, Takeuchi TAmerican Pancreatic Association and Japan Pancreas Society: Sisterhood Memorandum of Understanding.Pancreas ( 2017) 46(4): 453-454PMID : 28291160
• Matsubayashi H, Takaori K, Morizane C, Maguchi H, Mizuma M, Takahashi H, Wada K, Hosoi H, Yachida S, Suzuki M, Usui R, Furukawa T, Furuse J, Sato T, Ueno M, Kiyozumi Y, Hijioka S, Mizuno N, Terashima T, Mizumoto M, Kodama Y, Torishima M, Kawaguchi T, Ashida R, Kitano M, Hanada K, Furukawa M, Kawabe K, Majima Y, Shimosegawa TFamilial pancreatic cancer: Concept, management and issues.World J Gastroenterol ( 2017) 23(6): 935-948PMID : 28246467
• Teraoka R, Hara M, Kikuta K, Hirooka Y, Furutani Y, Shimosegawa T, Masamune A, Kojima SPlasma Kallikrein-Dependent Transforming Growth Factor-β Activation in Patients With Chronic Pancreatitis and Pancreatic Cancer.Pancreas ( 2017) 46(3): e20-e22PMID : 28187111
• Masamune A, Kikuta K, Nabeshima T, Nakano E, Hirota M, Kanno A, Kume K, Hamada S, Ito T, Fujita M, Irisawa A, Nakashima M, Hanada K, Eguchi T, Kato R, Inatomi O, Shirane A, Takeyama Y, Tsuji I, Shimosegawa TNationwide epidemiological survey of early chronic pancreatitis in Japan.J Gastroenterol ( 2017) PMID : 28130705
• Yoshida N, Masamune A, Hamada S, Kikuta K, Takikawa T, Motoi F, Unno M, Shimosegawa TKindlin-2 in pancreatic stellate cells promotes the progression of pancreatic cancer.Cancer Lett ( 2017) PMID : 28093281
• Hamada S, Masamune A, Kikuta K, Shimosegawa TDisseminated Intravascular Coagulation on Admission Predicts Complications and Poor Prognosis of Acute Pancreatitis: Analysis of the Nationwide Epidemiological Survey in Japan.Pancreas ( 2017) 46(2): e15-e16PMID : 28085757
• Kubota K, Kamisawa T, Okazaki K, Kawa S, Hirano K, Hirooka Y, Uchida K, Shiomi H, Ohara H, Shimizu K, Arakura N, Kanno A, Sakagami J, Itoi T, Ito T, Ueki T, Nishino T, Inui K, Mizuno N, Yoshida H, Sugiyama M, Iwasaki E, Irisawa A, Shimosegawa T, Takeyama Y, Chiba TLow-dose maintenance steroid treatment could reduce the relapse rate in patients with type 1 autoimmune pancreatitis: a long-term Japanese multicenter analysis of 510 patients.J Gastroenterol ( 2017) PMID : 28062947
• Okazaki K, Chari ST, Frulloni L, Lerch MM, Kamisawa T, Kawa S, Kim MH, Lévy P, Masamune A, Webster G, Shimosegawa TInternational consensus for the treatment of autoimmune pancreatitis.Pancreatology ( 2017) 17(1): 1-6PMID : 28027896
• Wu YS, Chung I, Wong WF, Masamune A, Sim MS, Looi CYParacrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells.Biochim Biophys Acta ( 2017) 1861(2): 296-306PMID : 27750041

2016年(29件)

• Kyakumoto Y, Mizuma M, Abe T, Takadate T, Fukase K, Otsuka H, Sakata N, Nakagawa K, Morikawa T, Hayashi H, Naitoh T, Motoi F, Kanno A, Shimosegawa T, Unno M[A Case of Successful Stomach-Preserving Pancreaticoduodenectomy with Celiac Artery Resection after Neoadjuvant Chemoradiation Therapy for Pancreatic Cancer with Hepatic Arterial Variation].Gan To Kagaku Ryoho ( 2016) 43(12): 1966-1968PMID : 28133191
• Tazuma S, Unno M, Igarashi Y, Inui K, Uchiyama K, Kai M, Tsuyuguchi T, Maguchi H, Mori T, Yamaguchi K, Ryozawa S, Nimura Y, Fujita N, Kubota K, Shoda J, Tabata M, Mine T, Sugano K, Watanabe M, Shimosegawa TEvidence-based clinical practice guidelines for cholelithiasis 2016.J Gastroenterol ( 2016) PMID : 27942871
• Takikawa T, Masamune A, Yoshida N, Hamada S, Kogure T, Shimosegawa TExosomes Derived From Pancreatic Stellate Cells: MicroRNA Signature and Effects on Pancreatic Cancer Cells.Pancreas ( 2016) PMID : 27841793
• Miura S, Kanno A, Masamune AReply to Angsuwatcharakon et al.Endoscopy ( 2016) 48(11): 1049-1050PMID : 27788543
• Waragai Y, Suzuki R, Takagi T, Sugimoto M, Asama H, Watanabe K, Kikuchi H, Hikichi T, Masamune A, Kang Y, Fleming JB, Ohira HClinical significance of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in pancreatic ductal adenocarcinoma.Pancreatology ( 2016) PMID : 27665173
• Hamada S, Masamune A, Shimosegawa TManagement of acute pancreatitis in Japan: Analysis of nationwide epidemiological survey.World J Gastroenterol ( 2016) 22(28): 6335-44PMID : 27605870
• Masamune A, Nishimori I, Kikuta K, Tsuji I, Mizuno N, Iiyama T, Kanno A, Tachibana Y, Ito T, Kamisawa T, Uchida K, Hamano H, Yasuda H, Sakagami J, Mitoro A, Taguchi M, Kihara Y, Sugimoto H, Hirooka Y, Yamamoto S, Inui K, Inatomi O, Andoh A, Nakahara K, Miyakawa H, Hamada S, Kawa S, Okazaki K, Shimosegawa TRandomised controlled trial of long-term maintenance corticosteroid therapy in patients with autoimmune pancreatitis.Gut ( 2016) PMID : 27543430
• Mine T, Takeyama Y, Shimosegawa TCurrent status of ERCP pancreatitis and matters in future.Nihon Shokakibyo Gakkai Zasshi ( 2016) 113(8): 1365-70PMID : 27498932
• Masamune A, Nakano E, Niihori T, Hamada S, Nagasaki M, Aoki Y, Shimosegawa TVariants in the UBR1 gene are not associated with chronic pancreatitis in Japan.Pancreatology ( 2016) PMID : 27397733
• Tanaka A, Takikawa H, Mochida S, Koike K, Miwa H, Shimosegawa TChanging nomenclature for PBC from "Primary Biliary Cirrhosis" to "Primary Biliary Cholangitis".Nihon Shokakibyo Gakkai Zasshi ( 2016) 113(7): 1165-1167PMID : 27383098
• Kuriyama S, Yaegashi N, Nagami F, Arai T, Kawaguchi Y, Osumi N, Sakaida M, Suzuki Y, Nakayama K, Hashizume H, Tamiya G, Kawame H, Suzuki K, Hozawa A, Nakaya N, Kikuya M, Metoki H, Tsuji I, Fuse N, Kiyomoto H, Sugawara J, Tsuboi A, Egawa S, Ito K, Chida K, Ishii T, Tomita H, Taki Y, Minegishi N, Ishii N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Koshiba S, Kinoshita K, Ogishima S, Takai-Igarashi T, Tominaga T, Tanabe O, Ohuchi N, Shimosegawa T, Kure S, Tanaka H, Ito S, Hitomi J, Tanno K, Nakamura M, Ogasawara K, Kobayashi S, Sakata K, Satoh M, Shimizu A, Sasaki M, Endo R, Sobue K, Study Group TT, Yamamoto MThe Tohoku Medical Megabank Project: Design and Mission.J Epidemiol ( 2016) PMID : 27374138
• Iwakiri K, Kinoshita Y, Habu Y, Oshima T, Manabe N, Fujiwara Y, Nagahara A, Kawamura O, Iwakiri R, Ozawa S, Ashida K, Ohara S, Kashiwagi H, Adachi K, Higuchi K, Miwa H, Fujimoto K, Kusano M, Hoshihara Y, Kawano T, Haruma K, Hongo M, Sugano K, Watanabe M, Shimosegawa TEvidence-based clinical practice guidelines for gastroesophageal reflux disease 2015.J Gastroenterol ( 2016) PMID : 27325300
• Fukui H, Saito H, Ueno Y, Uto H, Obara K, Sakaida I, Shibuya A, Seike M, Nagoshi S, Segawa M, Tsubouchi H, Moriwaki H, Kato A, Hashimoto E, Michitaka K, Murawaki T, Sugano K, Watanabe M, Shimosegawa TEvidence-based clinical practice guidelines for liver cirrhosis 2015.J Gastroenterol ( 2016) PMID : 27246107
• Tanaka A, Takikawa H, Mochida S, Koike K, Miwa H, Shimosegawa TChanging Nomenclature for PBC from J Gastroenterol ( 2016) PMID : 27230619
• Eguchi H, Yamaue H, Unno M, Mizuma M, Hamada S, Igarashi H, Kuroki T, Satoi S, Shimizu Y, Tani M, Tanno S, Hirooka Y, Fujii T, Masamune A, Mizumoto K, Itoi T, Egawa S, Kodama Y, Tanaka M, Shimosegawa TClinicopathological Characteristics of Young Patients With Pancreatic Cancer: An Analysis of Data From Pancreatic Cancer Registry of Japan Pancreas Society.Pancreas ( 2016) 45(10): 1411-1417PMID : 27171511
• Wu YS, Looi CY, Subramaniam KS, Masamune A, Chung ISoluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification.Oncotarget ( 2016) PMID : 27167341
• Takikawa T, Kanno A, Masamune A, Hongo S, Yoshida N, Nakano E, Miura S, Hamada S, Kume K, Kikuta K, Hirota M, Shimosegawa TEctopic Opening of the Common Bile Duct Accompanied by Choledochocele and Pancreas Divisum.Intern Med ( 2016) 55(9): 1097-102PMID : 27150861
• Hamada S, Masamune A, Kikuta K, Shimosegawa TClinical Impact of Elevated Serum Triglycerides in Acute Pancreatitis: Validation from the Nationwide Epidemiological Survey in Japan.Am J Gastroenterol ( 2016) 111(4): 575-6PMID : 27125713
• Tanaka A, Takikawa H, Miwa H, Shimosegawa T, Mochida S, Koike KChanging Nomenclature for PBC from "Primary Biliary Cirrhosis" to "Primary Biliary Cholangitis".Hepatol Res ( 2016) PMID : 27101399
• Kanno A, Masamune A, Fujishima F, Iwashita T, Kodama Y, Katanuma A, Ohara H, Kitano M, Inoue H, Itoi T, Mizuno N, Miyakawa H, Mikata R, Irisawa A, Sato S, Notohara K, Shimosegawa TDiagnosis of autoimmune pancreatitis by endoscopic ultrasonography -guided fine-needle aspiration using a 22-gauge needle: a prospective multicenter study.Gastrointest Endosc ( 2016) PMID : 27068878
• Miura S, Kanno A, Masamune A, Hamada S, Hongou S, Yoshida N, Nakano E, Takikawa T, Kume K, Kikuta K, Hirota M, Yoshida H, Katayose Y, Unno M, Shimosegawa TRisk factors for recurrent biliary obstruction following placement of self-expandable metallic stents in patients with malignant perihilar biliary stricture.Endoscopy ( 2016) PMID : 26987646
• Zou WB, Boulling A, Masamune A, Issarapu P, Masson E, Wu H, Sun XT, Hu LH, Zhou DZ, He L, Fichou Y, Nakano E, Hamada S, Kakuta Y, Kume K, Isayama H, Paliwal S, Mani KR, Bhaskar S, Cooper DN, Férec C, Shimosegawa T, Chandak GR, Chen JM, Li ZS, Liao ZNo Association Between CEL-HYB Hybrid Allele and Chronic Pancreatitis in Asian Populations.Gastroenterology ( 2016) 150(7): 1558-1560.e5PMID : 26946345
• Whitcomb DC, Frulloni L, Garg P, Greer JB, Schneider A, Yadav D, Shimosegawa TChronic pancreatitis: An international draft consensus proposal for a new mechanistic definition.Pancreatology ( 2016) PMID : 26924663
• Satoh K, Yoshino J, Akamatsu T, Itoh T, Kato M, Kamada T, Takagi A, Chiba T, Nomura S, Mizokami Y, Murakami K, Sakamoto C, Hiraishi H, Ichinose M, Uemura N, Goto H, Joh T, Miwa H, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for peptic ulcer disease 2015.J Gastroenterol ( 2016) PMID : 26879862
• Takasawa K, Miyakawa Y, Masamune A, Kashimada K, Shimohira MFibrocalculous pancreatic diabetes in a Japanese girl with severe motor and intellectual disabilities.Acta Diabetol ( 2016) PMID : 26782097
• Shimosegawa TTo establish the 'Early Chronic PancreatitisNihon Shokakibyo Gakkai Zasshi ( 2016) 113(1): 1-10PMID : 26743547
• Hamada S, Masamune A, Yoshida N, Takikawa T, Shimosegawa TIL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells.Dig Dis Sci ( 2016) PMID : 26738736
• Ito T, Ishiguro H, Ohara H, Kamisawa T, Sakagami J, Sata N, Takeyama Y, Hirota M, Miyakawa H, Igarashi H, Lee L, Fujiyama T, Hijioka M, Ueda K, Tachibana Y, Sogame Y, Yasuda H, Kato R, Kataoka K, Shiratori K, Sugiyama M, Okazaki K, Kawa S, Tando Y, Kinoshita Y, Watanabe M, Shimosegawa TEvidence-based clinical practice guidelines for chronic pancreatitis 2015.J Gastroenterol ( 2016) PMID : 26725837
• Kawakubo K, Ohnishi S, Fujita H, Kuwatani M, Onishi R, Masamune A, Takeda H, Sakamoto NEffect of Fetal Membrane-Derived Mesenchymal Stem Cell Transplantation in Rats With Acute and Chronic Pancreatitis.Pancreas ( 2016) 45(5): 707-13PMID : 26646279

2015年(25件)

• Masamune AAlcohol Misuse and Pancreatitis: A Lesson from Meta-Analysis.EBioMedicine ( 2015) 2(12): 1860-1PMID : 26844260
• Afghani E, Pandol SJ, Shimosegawa T, Sutton R, Wu BU, Vege SS, Gorelick F, Hirota M, Windsor J, Lo SK, Freeman ML, Lerch MM, Tsuji Y, Melmed GY, Wassef W, Mayerle JAcute Pancreatitis-Progress and Challenges: A Report on an International Symposium.Pancreas ( 2015) 44(8): 1195-210PMID : 26465949
• Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa TIgG4-unrelated type 1 autoimmune pancreatitis.World J Gastroenterol ( 2015) 21(33): 9808-16PMID : 26361429
• Inui K, Igarashi Y, Irisawa A, Ohara H, Tazuma S, Hirooka Y, Fujita N, Miyakawa H, Sata N, Shimosegawa T, Tanaka M, Shiratori K, Sugiyama M, Takeyama YJapanese Clinical Guidelines for Endoscopic Treatment of Pancreatolithiasis.Pancreas ( 2015) 44(7): 1053-64PMID : 26355548
• Notohara K, Nishimori I, Mizuno N, Okazaki K, Ito T, Kawa S, Egawa S, Kihara Y, Kanno A, Masamune A, Shimosegawa TClinicopathological Features of Type 2 Autoimmune Pancreatitis in Japan: Results of a Multicenter Survey.Pancreas ( 2015) 44(7): 1072-7PMID : 26335013
• Nakano E, Geisz A, Masamune A, Niihori T, Hamada S, Kume K, Kakuta Y, Aoki Y, Matsubara Y, Ebert K, Ludwig M, Braun M, Groneberg DA, Shimosegawa T, Sahin-Tóth M, Witt HVariants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis.Am J Physiol Gastrointest Liver Physiol ( 2015) 309(8): G688-94PMID : 26316592
• Masamune A, Shimosegawa TPancreatic stellate cells: A dynamic player of the intercellular communication in pancreatic cancer.Clin Res Hepatol Gastroenterol ( 2015) 39 Suppl 1 S98-S103PMID : 26189983
• Kikuta K, Masamune A, Shimosegawa TImpaired glucose tolerance in acute pancreatitis.World J Gastroenterol ( 2015) 21(24): 7367-74PMID : 26139984
• Fukudo S, Kaneko H, Akiho H, Inamori M, Endo Y, Okumura T, Kanazawa M, Kamiya T, Sato K, Chiba T, Furuta K, Yamato S, Arakawa T, Fujiyama Y, Azuma T, Fujimoto K, Mine T, Miura S, Kinoshita Y, Watanabe M, Sugano K, Shimosegawa TEvaluation of Kampo medicine in the clinical practice guideline for irritable bowel syndrome.J Gastroenterol ( 2015) 50(7): 817-8PMID : 26100007
• Masamune A, Nakano E, Hamada S, Kakuta Y, Kume K, Shimosegawa TCommon variants at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with chronic pancreatitis in Japan.Gut ( 2015) 64(8): 1345-6PMID : 26002935
• Hamada S, Masamune A, Kanno A, Shimosegawa TComprehensive Analysis of Serum microRNAs in Autoimmune Pancreatitis.Digestion ( 2015) 91(4): 263-71PMID : 25871699
• Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M, Takei Y, Takehara T, Tokushige K, Nakajima A, Yoneda M, Saibara T, Shiota G, Sakaida I, Nakamuta M, Mizuta T, Tsubouchi H, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.Hepatol Res ( 2015) 45(4): 363-77PMID : 25832328
• Mitsuyama T, Uchida K, Sumimoto K, Fukui Y, Ikeura T, Fukui T, Nishio A, Shikata N, Uemura Y, Satoi S, Mizuno N, Notohara K, Shimosegawa T, Zamboni G, Frulloni L, Okazaki KComparison of neutrophil infiltration between type 1 and type 2 autoimmune pancreatitis.Pancreatology ( 2015) 15(3): 271-80PMID : 25818196
• Kanno A, Masamune A, Okazaki K, Kamisawa T, Kawa S, Nishimori I, Tsuji I, Shimosegawa TNationwide epidemiological survey of autoimmune pancreatitis in Japan in 2011.Pancreas ( 2015) 44(4): 535-9PMID : 25815647
• Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M, Takei Y, Takehara T, Tokushige K, Nakajima A, Yoneda M, Saibara T, Shiota G, Sakaida I, Nakamuta M, Mizuta T, Tsubouchi H, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.J Gastroenterol ( 2015) 50(4): 364-77PMID : 25708290
• Miwa H, Kusano M, Arisawa T, Oshima T, Kato M, Joh T, Suzuki H, Tominaga K, Nakada K, Nagahara A, Futagami S, Manabe N, Inui A, Haruma K, Higuchi K, Yakabi K, Hongo M, Uemura N, Kinoshita Y, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for functional dyspepsia.J Gastroenterol ( 2015) 50(2): 125-39PMID : 25586651
• Tanaka S, Saitoh Y, Matsuda T, Igarashi M, Matsumoto T, Iwao Y, Suzuki Y, Nishida H, Watanabe T, Sugai T, Sugihara K, Tsuruta O, Hirata I, Hiwatashi N, Saito H, Watanabe M, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for management of colorectal polyps.J Gastroenterol ( 2015) 50(3): 252-60PMID : 25559129
• Fukudo S, Kaneko H, Akiho H, Inamori M, Endo Y, Okumura T, Kanazawa M, Kamiya T, Sato K, Chiba T, Furuta K, Yamato S, Arakawa T, Fujiyama Y, Azuma T, Fujimoto K, Mine T, Miura S, Kinoshita Y, Sugano K, Shimosegawa TEvidence-based clinical practice guidelines for irritable bowel syndrome.J Gastroenterol ( 2015) 50(1): 11-30PMID : 25500976
• Nakano E, Masamune A, Niihori T, Kume K, Hamada S, Aoki Y, Matsubara Y, Shimosegawa TTargeted next-generation sequencing effectively analyzed the cystic fibrosis transmembrane conductance regulator gene in pancreatitis.Dig Dis Sci ( 2015) 60(5): 1297-307PMID : 25492507
• Kawa S, Okazaki K, Notohara K, Watanabe M, Shimosegawa TAutoimmune pancreatitis complicated with inflammatory bowel disease and comparative study of type 1 and type 2 autoimmune pancreatitis.J Gastroenterol ( 2015) 50(7): 805-15PMID : 25399203
• Kume K, Masamune A, Ariga H, Shimosegawa TAlcohol Consumption and the Risk for Developing Pancreatitis: A Case-Control Study in Japan.Pancreas ( 2015) 44(1): 53-58PMID : 25386904
• Abue M, Yokoyama M, Shibuya R, Tamai K, Yamaguchi K, Sato I, Tanaka N, Hamada S, Shimosegawa T, Sugamura K, Satoh KCirculating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer.Int J Oncol ( 2015) 46(2): 539-47PMID : 25384963
• Miura S, Kanno A, Masamune A, Hamada S, Takikawa T, Nakano E, Yoshida N, Hongo S, Kikuta K, Kume K, Hirota M, Yoshida H, Katayose Y, Uuno M, Shimosegawa TBismuth classification is associated with the requirement for multiple biliary drainage in preoperative patients with malignant perihilar biliary stricture.Surg Endosc ( 2015) 29(7): 1862-70PMID : 25277483
• Satoh K, Hamada S, Shimosegawa TInvolvement of epithelial to mesenchymal transition in the development of pancreatic ductal adenocarcinoma.J Gastroenterol ( 2015) 50(2): 140-6PMID : 25216997
• Kanno A, Masamune A, Shimosegawa TEndoscopic approaches for the diagnosis of autoimmune pancreatitis.Dig Endosc ( 2015) 27(2): 250-8PMID : 25115499

2014年(24件)

• Kanno A, Masamune A, Hamada S, Kikuta K, Kume K, Hirota M, Shima K, Okada T, Motoi F, Fujishima F, Ishida K, Unno M, Shimosegawa TSudden disappearance of the blood flow in a case of pancreatic acinar cell carcinoma.Intern Med ( 2014) 53(22): 2589-93PMID : 25400180
• Shimosegawa T2014 Japan Pancreas Society Presidential Address: the American Pancreatic Association/Japan Pancreas Society joint meeting on the Big Island (the second American Pancreatic Association/Japan Pancreas Society joint meeting).Pancreas ( 2014) 43(8): 1130PMID : 25333394
• Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, Shimosegawa T, Apte MV, Wilson JS, Ng B, Lau SL, Gunton JE, Wahl GM, Hunter T, Drebin JA, O'Dwyer PJ, Liddle C, Tuveson DA, Downes M, Evans RMVitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.Cell ( 2014) 159(1): 80-93PMID : 25259922
• Hirota M, Shimosegawa T, Masamune A, Kikuta K, Kume K, Hamada S, Kanno A, Kimura K, Tsuji I, Kuriyama SThe seventh nationwide epidemiological survey for chronic pancreatitis in Japan: clinical significance of smoking habit in Japanese patients.Pancreatology ( 2014) 14(6): 490-6PMID : 25224249
• Hirota M, Mayumi T, Shimosegawa TAcute pancreatitis bundles: 10 clinical regulations for the early management of patients with severe acute pancreatitis in Japan.J Hepatobiliary Pancreat Sci ( 2014) 21(11): 829-30PMID : 25212096
• Nakano E, Masamune A, Kume K, Kakuta Y, Shimosegawa TVariants in the interferon regulatory factor-2 gene are not associated with pancreatitis in Japan.Pancreas ( 2014) 43(7): 1125-6PMID : 25207663
• Yamaguchi K, Okusaka T, Shimizu K, Furuse J, Ito Y, Hanada K, Shimosegawa TEBM-based Clinical Guidelines for Pancreatic Cancer (2013) issued by the Japan Pancreas Society: a synopsis.Jpn J Clin Oncol ( 2014) 44(10): 883-8PMID : 25205672
• Unno J, Kanno A, Masamune A, Kasajima A, Fujishima F, Ishida K, Hamada S, Kume K, Kikuta K, Hirota M, Motoi F, Unno M, Shimosegawa TThe usefulness of endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of pancreatic neuroendocrine tumors based on the World Health Organization classification.Scand J Gastroenterol ( 2014) 49(11): 1367-74PMID : 25180490
• Masamune ARecent advances in pancreatology.Front Physiol ( 2014) 5 300PMID : 25157235
• Hamada S, Masamune A, Kikuta K, Hirota M, Tsuji I, Shimosegawa TNationwide epidemiological survey of acute pancreatitis in Japan.Pancreas ( 2014) 43(8): 1244-8PMID : 25084001
• Song TJ, Kim MH, Kim MJ, Moon SH, Han JMClinical validation of the international consensus diagnostic criteria and algorithms for autoimmune pancreatitis: combined IAP and KPBA meeting 2013 report.Pancreatology ( 2014) 14(4): 233-7PMID : 25062869
• Kawa S, Okazaki K, Kamisawa T, Kubo K, Ohara H, Hasebe O, Fujinaga Y, Irisawa A, Notohara K, Ito T, Inui K, Irie H, Nishino T, Nishimori I, Tanaka S, Nishiyama T, Suda K, Shiratori K, Tanaka M, Shimosegawa TAmendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 II. Extrapancreatic lesions, differential diagnosis.J Gastroenterol ( 2014) 49(5): 765-84PMID : 24664402
• Kamisawa T, Okazaki K, Kawa S, Ito T, Inui K, Irie H, Nishino T, Notohara K, Nishimori I, Tanaka S, Nishiyama T, Suda K, Shiratori K, Tanaka M, Shimosegawa TAmendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis.J Gastroenterol ( 2014) 49(6): 961-70PMID : 24639058
• Okazaki K, Kawa S, Kamisawa T, Ito T, Inui K, Irie H, Nishino T, Notohara K, Nishimori I, Tanaka S, Nishiyama T, Suda K, Shiratori K, Tanaka M, Shimosegawa TAmendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 I. Concept and diagnosis of autoimmune pancreatitis.J Gastroenterol ( 2014) 49(4): 567-88PMID : 24639057
• Kataoka K, Sakagami J, Hirota M, Masamune A, Shimosegawa TEffects of oral ingestion of the elemental diet in patients with painful chronic pancreatitis in the real-life setting in Japan.Pancreas ( 2014) 43(3): 451-7PMID : 24622078
• Masamune AGenetics of pancreatitis: the 2014 update.Tohoku J Exp Med ( 2014) 232(2): 69-77PMID : 24522117
• Masamune A, Nakano E, Hamada S, Takikawa T, Yoshida N, Shimosegawa TAlteration of the microRNA expression profile during the activation of pancreatic stellate cells.Scand J Gastroenterol ( 2014) 49(3): 323-31PMID : 24404812
• Miura S, Hamada S, Masamune A, Satoh K, Shimosegawa TCUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells.Exp Cell Res ( 2014) 321(2): 209-18PMID : 24384474
• Kamisawa T, Chari ST, Lerch MM, Kim MH, Gress TM, Shimosegawa TRepublished: recent advances in autoimmune pancreatitis: type 1 and type 2.Postgrad Med J ( 2014) 90(1059): 18-25PMID : 24336310
• Unno J, Masamune A, Hamada S, Shimosegawa TThe zinc transporter LIV-1 is a novel regulator of stemness in pancreatic cancer cells.Scand J Gastroenterol ( 2014) 49(2): 215-21PMID : 24294832
• Hamada S, Masamune A, Shimosegawa TInflammation and pancreatic cancer: disease promoter and new therapeutic target.J Gastroenterol ( 2014) 49(4): 605-17PMID : 24292163
• Hamada S, Masamune A, Miura S, Satoh K, Shimosegawa TMiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX.Cell Signal ( 2014) 26(2): 179-85PMID : 24216611
• Yuhara H, Ogawa M, Kawaguchi Y, Igarashi M, Shimosegawa T, Mine TPharmacologic prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: protease inhibitors and NSAIDs in a meta-analysis.J Gastroenterol ( 2014) 49(3): 388-99PMID : 23720090
• Masamune A, Nakano E, Kume K, Takikawa T, Kakuta Y, Shimosegawa TPRSS1 c.623G>C (p.G208A) variant is associated with pancreatitis in Japan.Gut ( 2014) 63(2): 366PMID : 23686146

2013年(25件)

• Okada T, Motoi F, Kanno A, Masamune A, Ishida K, Fujishima F, Rikiyama T, Katayose Y, Egawa S, Shimosegawa T, Unno MPancreatic intraepithelial neoplasia-3 with localized acute pancreatitis in the main pancreatic duct.Clin J Gastroenterol ( 2013) 6(2): 164-8PMID : 26181456
• Hata T, Sakata N, Aoki T, Yoshida H, Kanno A, Fujishima F, Motoi F, Masamune A, Shimosegawa T, Unno MRepeated pancreatectomy for metachronous duodenal and pancreatic metastases of renal cell carcinoma.Case Rep Gastroenterol ( 2013) 7(3): 442-8PMID : 24403883
• Hamada S, Masamune A, Shimosegawa TNovel therapeutic strategies targeting tumor-stromal interactions in pancreatic cancer.Front Physiol ( 2013) 4 331PMID : 24273517
• Hamada S, Masamune A, Shimosegawa TAlteration of pancreatic cancer cell functions by tumor-stromal cell interaction.Front Physiol ( 2013) 4 318PMID : 24198790
• Awano H, Lee T, Yagi M, Masamune A, Kume K, Takeshima Y, Iijima KChildhood-onset hereditary pancreatitis with mutations in the CT gene and SPINK1 gene.Pediatr Int ( 2013) 55(5): 646-9PMID : 24134754
• Koizumi S, Kamisawa T, Kuruma S, Tabata T, Chiba K, Iwasaki S, Endo Y, Kuwata G, Koizumi K, Shimosegawa T, Okazaki K, Chiba TImmunoglobulin G4-related gastrointestinal diseases, are they immunoglobulin G4-related diseases?World J Gastroenterol ( 2013) 19(35): 5769-74PMID : 24124321
• Working Group IAP/APA Acute Pancreatitis Guidelines.IAP/APA evidence-based guidelines for the management of acute pancreatitis.Pancreatology ( 2013) 13(4 Suppl 2): e1-15PMID : 24054878
• Takikawa T, Kanno A, Masamune A, Hamada S, Nakano E, Miura S, Ariga H, Unno J, Kume K, Kikuta K, Hirota M, Yoshida H, Katayose Y, Unno M, Shimosegawa TPancreatic duct drainage using EUS-guided rendezvous technique for stenotic pancreaticojejunostomy.World J Gastroenterol ( 2013) 19(31): 5182-6PMID : 23964156
• Witt H, Beer S, Rosendahl J, Chen JM, Chandak GR, Masamune A, Bence M, Szmola R, Oracz G, Macek M Jr, Bhatia E, Steigenberger S, Lasher D, Bühler F, Delaporte C, Tebbing J, Ludwig M, Pilsak C, Saum K, Bugert P, Masson E, Paliwal S, Bhaskar S, Sobczynska-Tomaszewska A, Bak D, Balascak I, Choudhuri G, Nageshwar Reddy D, Rao GV, Thomas V, Kume K, Nakano E, Kakuta Y, Shimosegawa T, Durko L, Szabó A, Schnúr A, Hegyi P, Rakonczay Z Jr, Pfützer R, Schneider A, Groneberg DA, Braun M, Schmidt H, Witt U, Friess H, Algül H, Landt O, Schuelke M, Krüger R, Wiedenmann B, Schmidt F, Zimmer KP, Kovacs P, Stumvoll M, Blüher M, Müller T, Janecke A, Teich N, Grützmann R, Schulz HU, Mössner J, Keim V, Löhr M, Férec C, Sahin-Tóth MVariants in CPA1 are strongly associated with early onset chronic pancreatitis.Nat Genet ( 2013) 45(10): 1216-20PMID : 23955596
• Kamisawa T, Ryu JK, Kim MH, Okazaki K, Shimosegawa T, Chung JBRecent advances in the diagnosis and management of autoimmune pancreatitis: similarities and differences in Japan and Korea.Gut Liver ( 2013) 7(4): 394-400PMID : 23898377
• Takikawa T, Masamune A, Hamada S, Nakano E, Yoshida N, Shimosegawa TmiR-210 regulates the interaction between pancreatic cancer cells and stellate cells.Biochem Biophys Res Commun ( 2013) 437(3): 433-9PMID : 23831622
• Yasuda I, Nakashima M, Iwai T, Isayama H, Itoi T, Hisai H, Inoue H, Kato H, Kanno A, Kubota K, Irisawa A, Igarashi H, Okabe Y, Kitano M, Kawakami H, Hayashi T, Mukai T, Sata N, Kida M, Shimosegawa TJapanese multicenter experience of endoscopic necrosectomy for infected walled-off pancreatic necrosis: The JENIPaN study.Endoscopy ( 2013) 45(8): 627-34PMID : 23807806
• Kamisawa T, Chari ST, Lerch MM, Kim MH, Gress TM, Shimosegawa TRecent advances in autoimmune pancreatitis: type 1 and type 2.Gut ( 2013) 62(9): 1373-80PMID : 23749606
• Ohara H, Nakazawa T, Kawa S, Kamisawa T, Shimosegawa T, Uchida K, Hirano K, Nishino T, Hamano H, Kanno A, Notohara K, Hasebe O, Muraki T, Ishida E, Naitoh I, Okazaki KEstablishment of a serum IgG4 cut-off value for the differential diagnosis of IgG4-related sclerosing cholangitis: a Japanese cohort.J Gastroenterol Hepatol ( 2013) 28(7): 1247-51PMID : 23621484
• Tahara H, Sato K, Yamazaki Y, Ohyama T, Horiguchi N, Hashizume H, Kakizaki S, Takagi H, Ozaki I, Arai H, Hirato J, Jesenofsky R, Masamune A, Mori MTransforming growth factor-α activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation.Lab Invest ( 2013) 93(6): 720-32PMID : 23608755
• Wada K, Takaori K, Traverso LW, Hruban RH, Furukawa T, Brentnall TA, Hatori T, Sano K, Takada T, Majima Y, Shimosegawa TClinical importance of Familial Pancreatic Cancer Registry in Japan: a report from kick-off meeting at International Symposium on Pancreas Cancer 2012.J Hepatobiliary Pancreat Sci ( 2013) 20(6): 557-66PMID : 23604538
• Masamune A, Shimosegawa TPancreatic stellate cells--multi-functional cells in the pancreas.Pancreatology ( 2013) 13(2): 102-5PMID : 23561965
• Masamune A, Kume K, Shimosegawa TSex and age differences in alcoholic pancreatitis in Japan: a multicenter nationwide survey.Pancreas ( 2013) 42(4): 578-83PMID : 23508016
• Kikuta K, Masamune A, Hamada S, Takikawa T, Nakano E, Shimosegawa TPancreatic stellate cells reduce insulin expression and induce apoptosis in pancreatic β-cells.Biochem Biophys Res Commun ( 2013) 433(3): 292-7PMID : 23500461
• Masamune A, Hamada S, Kikuta K, Takikawa T, Miura S, Nakano E, Shimosegawa TThe angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice.Scand J Gastroenterol ( 2013) 48(5): 602-9PMID : 23477656
• Hart PA, Kamisawa T, Brugge WR, Chung JB, Culver EL, Czakó L, Frulloni L, Go VL, Gress TM, Kim MH, Kawa S, Lee KT, Lerch MM, Liao WC, Löhr M, Okazaki K, Ryu JK, Schleinitz N, Shimizu K, Shimosegawa T, Soetikno R, Webster G, Yadav D, Zen Y, Chari STLong-term outcomes of autoimmune pancreatitis: a multicentre, international analysis.Gut ( 2013) 62(12): 1771-6PMID : 23232048
• Hamada S, Satoh K, Miura S, Hirota M, Kanno A, Masamune A, Kikuta K, Kume K, Unno J, Egawa S, Motoi F, Unno M, Shimosegawa TmiR-197 induces epithelial-mesenchymal transition in pancreatic cancer cells by targeting p120 catenin.J Cell Physiol ( 2013) 228(6): 1255-63PMID : 23139153
• Masamune A, Nakano E, Kume K, Kakuta Y, Ariga H, Shimosegawa TIdentification of novel missense CTRC variants in Japanese patients with chronic pancreatitis.Gut ( 2013) 62(4): 653-4PMID : 23135764
• Ueda J, Tanaka M, Ohtsuka T, Tokunaga S, Shimosegawa TSurgery for chronic pancreatitis decreases the risk for pancreatic cancer: a multicenter retrospective analysis.Surgery ( 2013) 153(3): 357-64PMID : 22989892
• Masamune A, Suzuki N, Kikuta K, Ariga H, Hayashi S, Takikawa T, Kume K, Hamada S, Hirota M, Kanno A, Egawa S, Unno M, Shimosegawa TConnexins regulate cell functions in pancreatic stellate cells.Pancreas ( 2013) 42(2): 308-16PMID : 22889984

2012年(20件)

• Satoh K, Hamada S, Shimosegawa TMSX2 in pancreatic tumor development and its clinical application for the diagnosis of pancreatic ductal adenocarcinoma.Front Physiol ( 2012) 3 430PMID : 23162473
• Shimosegawa TThe amendment of the Clinical Diagnostic Criteria in Japan (JPS2011) in response to the proposal of the International Consensus of Diagnostic Criteria (ICDC) for autoimmune pancreatitis.Pancreas ( 2012) 41(8): 1341-2PMID : 23086247
• Freeman ML, Werner J, van Santvoort HC, Baron TH, Besselink MG, Windsor JA, Horvath KD, vanSonnenberg E, Bollen TL, Vege SSInterventions for necrotizing pancreatitis: summary of a multidisciplinary consensus conference.Pancreas ( 2012) 41(8): 1176-94PMID : 23086243
• Kamisawa T, Tabata T, Hara S, Kuruma S, Chiba K, Kanno A, Masamune A, Shimosegawa TRecent advances in autoimmune pancreatitis.Front Physiol ( 2012) 3 374PMID : 23060806
• Hirota M, Shimosegawa T, Kanno A, Kikuta K, Kume K, Hamada S, Unno J, Masamune ADistinct clinical features of two patients that progressed from the early phase of chronic pancreatitis to the advanced phase.Tohoku J Exp Med ( 2012) 228(3): 173-80PMID : 23037129
• Hamada S, Satoh K, Masamune A, Shimosegawa TRegulators of epithelial mesenchymal transition in pancreatic cancer.Front Physiol ( 2012) 3 254PMID : 22934011
• Uchida K, Masamune A, Shimosegawa T, Okazaki KPrevalence of IgG4-Related Disease in Japan Based on Nationwide Survey in 2009.Int J Rheumatol ( 2012) 2012 358371PMID : 22899936
• Kanno A, Ishida K, Hamada S, Fujishima F, Unno J, Kume K, Kikuta K, Hirota M, Masamune A, Satoh K, Notohara K, Shimosegawa TDiagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria.Gastrointest Endosc ( 2012) 76(3): 594-602PMID : 22898417
• Hamada S, Shimosegawa TPancreatic cancer stem cell and mesenchymal stem cellPancreatic Cancer and Tumor Microenvironment ( 2012) PMID : 22876386
• Dellinger EP, Forsmark CE, Layer P, Lévy P, Maraví-Poma E, Petrov MS, Shimosegawa T, Siriwardena AK, Uomo G, Whitcomb DC, Windsor JADeterminant-based classification of acute pancreatitis severity: an international multidisciplinary consultation.Ann Surg ( 2012) 256(6): 875-80PMID : 22735715
• Hirota M, Satoh K, Kikuta K, Masamune A, Kume K, Hamada S, Satoh A, Kanno A, Unno J, Ito H, Ariga H, Shimosegawa TEarly detection of low enhanced pancreatic parenchyma by contrast-enhanced computed tomography predicts poor prognosis of patients with acute pancreatitis.Pancreas ( 2012) 41(7): 1099-104PMID : 22699199
• Kanno A, Masamune A, Hirota M, Kikuta K, Shimosegawa TSuccessful treatment of benign biliary stricture by a covered self-expandable metallic stent in a patient with chronic pancreatitis.Dig Endosc ( 2012) 24 Suppl 1 43-8PMID : 22533751
• Kawaguchi Y, Ogawa M, Omata F, Ito H, Shimosegawa T, Mine TRandomized controlled trial of pancreatic stenting to prevent pancreatitis after endoscopic retrograde cholangiopancreatography.World J Gastroenterol ( 2012) 18(14): 1635-41PMID : 22529693
• Kume K, Masamune A, Ariga H, Hayashi S, Takikawa T, Miura S, Suzuki N, Kikuta K, Hamada S, Hirota M, Kanno A, Shimosegawa TDo genetic variants in the SPINK1 gene affect the level of serum PSTI?J Gastroenterol ( 2012) 47(11): 1267-74PMID : 22526274
• Hamada S, Masamune A, Takikawa T, Suzuki N, Kikuta K, Hirota M, Hamada H, Kobune M, Satoh K, Shimosegawa TPancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells.Biochem Biophys Res Commun ( 2012) 421(2): 349-54PMID : 22510406
• Hirota M, Shimosegawa T, Masamune A, Kikuta K, Kume K, Hamada S, Kihara Y, Satoh A, Kimura K, Tsuji I, Kuriyama SThe sixth nationwide epidemiological survey of chronic pancreatitis in Japan.Pancreatology ( 2012) 12(2): 79-84PMID : 22487515
• Kanno A, Nishimori I, Masamune A, Kikuta K, Hirota M, Kuriyama S, Tsuji I, Shimosegawa TNationwide epidemiological survey of autoimmune pancreatitis in Japan.Pancreas ( 2012) 41(6): 835-9PMID : 22466167
• Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson JStellaTUM: current consensus and discussion on pancreatic stellate cell research.Gut ( 2012) 61(2): 172-8PMID : 22115911
• Hamada S, Satoh K, Fujibuchi W, Hirota M, Kanno A, Unno J, Masamune A, Kikuta K, Kume K, Shimosegawa TMiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9.Mol Cancer Res ( 2012) 10(1): 3-10PMID : 22064652
• Hamada S, Satoh K, Hirota M, Kanno A, Umino J, Ito H, Masamune A, Kikuta K, Kume K, Shimosegawa TThe homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2.J Cell Physiol ( 2012) 227(2): 729-38PMID : 21465479

2011年(21件)

• Komatsu H, Yoshida H, Hayashi H, Sakata N, Morikawa T, Onogawa T, Motoi F, Rikiyama T, Katayose Y, Egawa S, Hirota M, Shimosegawa T, Unno MFulminant type of emphysematous pancreatitis has risk of massive hemorrhage.Clin J Gastroenterol ( 2011) 4(4): 249-54PMID : 26189529
• Katayose Y, Rikiyama T, Motoi F, Yamamoto K, Yoshida H, Morikawa T, Hayashi H, Kanno A, Hirota M, Satoh K, Ariga H, Suzuki M, Ohyauchi M, Kondo Y, Ikeya S, Ogawa Y, Shimosegawa T, Egawa S, Unno MPhase I trial of neoadjuvant chemoradiation with gemcitabine and surgical resection for cholangiocarcinoma patients (NACRAC study).Hepatogastroenterology ( 2011) 58(112): 1866-72PMID : 22234055
• Kamisawa T, Shimosegawa TPancreas: Histological diagnostic criteria for autoimmune pancreatitis.Nat Rev Gastroenterol Hepatol ( 2011) 9(1): 8-10PMID : 22158378
• Yamaguchi H, Kuboki Y, Hatori T, Yamamoto M, Shiratori K, Kawamura S, Kobayashi M, Shimizu M, Ban S, Koyama I, Higashi M, Shin N, Ishida K, Morikawa T, Motoi F, Unno M, Kanno A, Satoh K, Shimosegawa T, Orikasa H, Watanabe T, Nishimura K, Harada Y, Furukawa TSomatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.Am J Surg Pathol ( 2011) 35(12): 1812-7PMID : 21945955
• Hirota M, Asakura T, Kanno A, Kikuta K, Kume K, Hamada S, Unno J, Ito H, Ariga H, Masamune A, Satoh K, Motoi F, Egawa S, Unno M, Shimosegawa TLong-period pancreatic stenting for painful chronic calcified pancreatitis required higher medical costs and frequent hospitalizations compared with surgery.Pancreas ( 2011) 40(6): 946-50PMID : 21747315
• Kamisawa T, Chari ST, Giday SA, Kim MH, Chung JB, Lee KT, Werner J, Bergmann F, Lerch MM, Mayerle J, Pickartz T, Lohr M, Schneider A, Frulloni L, Webster GJ, Reddy DN, Liao WC, Wang HP, Okazaki K, Shimosegawa T, Kloeppel G, Go VLClinical profile of autoimmune pancreatitis and its histological subtypes: an international multicenter survey.Pancreas ( 2011) 40(6): 809-14PMID : 21747310
• Hirota M, Tsuda M, Tsuji Y, Kanno A, Kikuta K, Kume K, Hamada S, Unno J, Ito H, Ariga H, Chiba T, Masamune A, Satoh K, Shimosegawa TPerfusion computed tomography findings of autoimmune pancreatitis.Pancreas ( 2011) 40(8): 1295-301PMID : 21705954
• Kalaitzakis E, Levy M, Kamisawa T, Johnson GJ, Baron TH, Topazian MD, Takahashi N, Kanno A, Okazaki K, Egawa N, Uchida K, Sheikh K, Amin Z, Shimosegawa T, Sandanayake NS, Church NI, Chapman MH, Pereira SP, Chari S, Webster GJEndoscopic retrograde cholangiography does not reliably distinguish IgG4-associated cholangitis from primary sclerosing cholangitis or cholangiocarcinoma.Clin Gastroenterol Hepatol ( 2011) 9(9): 800-803.e2PMID : 21699807
• Kanno A, Satoh K, Hamada S, Hirota M, Masamune A, Motoi F, Egawa S, Unno M, Ishida K, Kimura K, Shuin T, Shimosegawa TSerous cystic neoplasms of the whole pancreas in a patient with von Hippel-Lindau disease.Intern Med ( 2011) 50(12): 1293-8PMID : 21673464
• Ito T, Nakamura T, Fujimori N, Niina Y, Igarashi H, Oono T, Uchida M, Kawabe K, Takayanagi R, Nishimori I, Otsuki M, Shimosegawa TCharacteristics of pancreatic diabetes in patients with autoimmune pancreatitis.J Dig Dis ( 2011) 12(3): 210-6PMID : 21615876
• Mantoni TS, Lunardi S, Al-Assar O, Masamune A, Brunner TBPancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.Cancer Res ( 2011) 71(10): 3453-8PMID : 21558392
• Satoh K, Shimosegawa T, Masamune A, Hirota M, Kikuta K, Kihara Y, Kuriyama S, Tsuji I, Satoh A, Hamada SNationwide epidemiological survey of acute pancreatitis in Japan.Pancreas ( 2011) 40(4): 503-7PMID : 21499203
• Ito H, Satoh K, Hamada S, Hirota M, Kanno A, Ishida K, Unno J, Masamune A, Katayose Y, Unno M, Shimosegawa TThe evaluation of MSX2 mRNA expression level in biliary brush cytological specimens.Anticancer Res ( 2011) 31(3): 1011-7PMID : 21498730
• Hamada S, Shimosegawa TBiomarkers of pancreatic cancer.Pancreatology ( 2011) 11 Suppl 2 14-9PMID : 21464582
• Kudo M, Yamao K, Shimosegawa TThe prognosis of patients with pancreatic cancer is extremely poor. Preface.Pancreatology ( 2011) 11 Suppl 2 1-2PMID : 21464579
• Shimosegawa T, Chari ST, Frulloni L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Klöppel G, Lerch MM, Löhr M, Notohara K, Okazaki K, Schneider A, Zhang LInternational consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology.Pancreas ( 2011) 40(3): 352-8PMID : 21412117
• Kamisawa T, Kim MH, Liao WC, Liu Q, Balakrishnan V, Okazaki K, Shimosegawa T, Chung JB, Lee KT, Wang HP, Lee TC, Choudhuri GClinical characteristics of 327 Asian patients with autoimmune pancreatitis based on Asian diagnostic criteria.Pancreas ( 2011) 40(2): 200-5PMID : 21404457
• Masamune A, Ariga H, Kume K, Kakuta Y, Satoh K, Satoh A, Shimosegawa TGenetic background is different between sentinel and recurrent acute pancreatitis.J Gastroenterol Hepatol ( 2011) 26(6): 974-8PMID : 21303407
• Hamada S, Satoh K, Hirota M, Kanno A, Ishida K, Umino J, Ito H, Kikuta K, Kume K, Masamune A, Katayose Y, Unno M, Shimosegawa TCalcium-binding protein S100P is a novel diagnostic marker of cholangiocarcinoma.Cancer Sci ( 2011) 102(1): 150-6PMID : 21029254
• Satoh K, Hamada S, Kanno A, Ishida K, Ito H, Hirota M, Masamune A, Egawa S, Unno M, Shimosegawa TEvaluation of MSX2 mRNA in brush cytology specimens distinguished pancreatic carcinoma from chronic pancreatitis.Cancer Sci ( 2011) 102(1): 157-61PMID : 20961362
• Takanami K, Yamada T, Tsuda M, Takase K, Ishida K, Nakamura Y, Kanno A, Shimosegawa T, Unno M, Takahashi SIntraductal papillary mucininous neoplasm of the bile ducts: multimodality assessment with pathologic correlation.Abdom Imaging ( 2011) 36(4): 447-56PMID : 20959978

2010年(20件)

• Chari ST, Kloeppel G, Zhang L, Notohara K, Lerch MM, Shimosegawa THistopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document.Pancreatology ( 2010) 10(6): 664-72PMID : 21242705
• Kanno A, Satoh K, Hirota M, Hamada S, Umino J, Itoh H, Masamune A, Egawa S, Motoi F, Unno M, Ishida K, Shimosegawa TGranular cell tumor of the pancreas: A case report and review of literature.World J Gastrointest Oncol ( 2010) 2(2): 121-4PMID : 21160931
• Kikuta K, Masamune A, Watanabe T, Ariga H, Itoh H, Hamada S, Satoh K, Egawa S, Unno M, Shimosegawa TPancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells.Biochem Biophys Res Commun ( 2010) 403(3-4): 380-4PMID : 21081113
• Masamune A, Watanabe T, Kikuta K, Satoh K, Kanno A, Shimosegawa TNuclear expression of interleukin-33 in pancreatic stellate cells.Am J Physiol Gastrointest Liver Physiol ( 2010) 299(4): G821-32PMID : 20689058
• Kamisawa T, Notohara K, Shimosegawa TTwo clinicopathologic subtypes of autoimmune pancreatitis: LPSP and IDCP.Gastroenterology ( 2010) 139(1): 22-5PMID : 20639082
• Chari ST, Kloeppel G, Zhang L, Notohara K, Lerch MM, Shimosegawa THistopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document.Pancreas ( 2010) 39(5): 549-54PMID : 20562576
• Ota Y, Masamune A, Inui K, Kume K, Shimosegawa T, Kikuyama MPhenotypic variability of the homozygous IVS3+2T>C mutation in the serine protease inhibitor Kazal type 1 (SPINK1) gene in patients with chronic pancreatitis.Tohoku J Exp Med ( 2010) 221(3): 197-201PMID : 20543535
• Takasawa S, Kuroki M, Nata K, Noguchi N, Ikeda T, Yamauchi A, Ota H, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Takahashi I, Yoshikawa T, Shimosegawa T, Okamoto HA novel ryanodine receptor expressed in pancreatic islets by alternative splicing from type 2 ryanodine receptor gene.Biochem Biophys Res Commun ( 2010) 397(2): 140-5PMID : 20471962
• Shimosegawa T, Kataoka K, Kamisawa T, Miyakawa H, Ohara H, Ito T, Naruse S, Sata N, Suda K, Hirota M, Takeyama Y, Shiratori K, Hatori T, Otsuki M, Atomi Y, Sugano K, Tanaka MThe revised Japanese clinical diagnostic criteria for chronic pancreatitis.J Gastroenterol ( 2010) 45(6): 584-91PMID : 20422433
• Kanno A, Satoh K, Hirota M, Hamada S, Umino J, Itoh H, Masamune A, Asakura T, Shimosegawa TPrediction of invasive carcinoma in branch type intraductal papillary mucinous neoplasms of the pancreas.J Gastroenterol ( 2010) 45(9): 952-9PMID : 20383536
• Kamisawa T, Okazaki K, Kawa S, Shimosegawa T, Tanaka MJapanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP.J Gastroenterol ( 2010) 45(5): 471-7PMID : 20213336
• Ito T, Otsuki M, Igarashi H, Kihara Y, Kawabe K, Nakamura T, Fujimori N, Oono T, Takayanagi R, Shimosegawa TEpidemiological study of pancreatic diabetes in Japan in 2005: a nationwide study.Pancreas ( 2010) 39(6): 829-35PMID : 20182396
• Satoh K, Hamada S, Kanno A, Hirota M, Umino J, Ito H, Masamune A, Egawa S, Unno M, Shimosegawa TExpression of MSX2 predicts malignancy of branch duct intraductal papillary mucinous neoplasm of the pancreas.J Gastroenterol ( 2010) 45(7): 763-70PMID : 20107842
• Takada T, Hirata K, Mayumi T, Yoshida M, Sekimoto M, Hirota M, Kimura Y, Takeda K, Isaji S, Wada K, Amano H, Gabata T, Arata S, Hirota M, Yokoe M, Kiriyama S, Nakayama T, Otomo K, Tanaka M, Shimosegawa TCutting-edge information for the management of acute pancreatitis.J Hepatobiliary Pancreat Sci ( 2010) 17(1): 3-12PMID : 20020160
• Hirota M, Takada T, Kitamura N, Ito T, Hirata K, Yoshida M, Mayumi T, Kataoka K, Takeda K, Sekimoto M, Hirota M, Kimura Y, Wada K, Amano H, Gabata T, Arata S, Yokoe M, Kiriyama SFundamental and intensive care of acute pancreatitis.J Hepatobiliary Pancreat Sci ( 2010) 17(1): 45-52PMID : 20012652
• Takeda K, Yokoe M, Takada T, Kataoka K, Yoshida M, Gabata T, Hirota M, Mayumi T, Kadoya M, Yamanouchi E, Hattori T, Sekimoto M, Amano H, Wada K, Kimura Y, Kiriyama S, Arata S, Takeyama Y, Hirota M, Hirata K, Shimosegawa TAssessment of severity of acute pancreatitis according to new prognostic factors and CT grading.J Hepatobiliary Pancreat Sci ( 2010) 17(1): 37-44PMID : 20012329
• Mayumi T, Takada T, Hirata K, Yoshida M, Sekimoto M, Hirota M, Kimura Y, Takeda K, Amano H, Wada K, Gabata T, Arata S, Hirota M, Yokoe M, Kiriyama S, Shikata S, Shirai K, Nakayama T, Ohtomo K, Tanaka M, Shimosegawa TPancreatitis bundles.J Hepatobiliary Pancreat Sci ( 2010) 17(1): 87-9PMID : 20012324
• Masamune A, Kume K, Kikuta K, Watanabe T, Hirota M, Satoh K, Kanno A, Suzuki N, Kakuta Y, Shimosegawa T-651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in Japan.J Gastroenterol ( 2010) 45(2): 225-33PMID : 19997857
• Hirota M, Asakura T, Kanno A, Shimosegawa TEndoscopic treatment for chronic pancreatitis: indications, technique, results.J Hepatobiliary Pancreat Sci ( 2010) 17(6): 770-5PMID : 19826752
• Masamune A, Satoh A, Watanabe T, Kikuta K, Satoh M, Suzuki N, Satoh K, Shimosegawa TEffects of ethanol and its metabolites on human pancreatic stellate cells.Dig Dis Sci ( 2010) 55(1): 204-11PMID : 19165599

2009年(17件)

• Masamune A, Watanabe T, Kikuta K, Shimosegawa TRoles of pancreatic stellate cells in pancreatic inflammation and fibrosis.Clin Gastroenterol Hepatol ( 2009) 7(11 Suppl): S48-54PMID : 19896099
• Shimosegawa T, Kume K, Satoh KChronic pancreatitis and pancreatic cancer: prediction and mechanism.Clin Gastroenterol Hepatol ( 2009) 7(11 Suppl): S23-8PMID : 19896093
• Shimosegawa T, Gorelick FSInflammation and carcinogenesis in the pancreas and biliary tract: mechanisms and practice.Clin Gastroenterol Hepatol ( 2009) 7(11 Suppl): S1-2PMID : 19896089
• Go VL, Myers D, Shimosegawa TCongratulations on the 40th anniversaries of the American Pancreatic Association and Japan Pancreas Society.Pancreas ( 2009) 38(8): 843PMID : 19855229
• Watanabe T, Masamune A, Kikuta K, Hirota M, Kume K, Satoh K, Shimosegawa TBone marrow contributes to the population of pancreatic stellate cells in mice.Am J Physiol Gastrointest Liver Physiol ( 2009) 297(6): G1138-46PMID : 19808658
• Unno J, Satoh K, Hirota M, Kanno A, Hamada S, Ito H, Masamune A, Tsukamoto N, Motoi F, Egawa S, Unno M, Horii A, Shimosegawa TLIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells.Int J Oncol ( 2009) 35(4): 813-21PMID : 19724917
• Seo JY, Masamune A, Shimosegawa T, Kim HProtective effect of lycopene on oxidative stress-induced cell death of pancreatic acinar cells.Ann N Y Acad Sci ( 2009) 1171 570-5PMID : 19723106
• Ogihara T, Katagiri H, Yamada T, Kudo H, Imai J, Ishigaki Y, Hinokio Y, Yamagiwa Y, Ueno Y, Shimosegawa T, Oka YPeginterferon (PEG-IFN) plus ribavirin combination therapy, but neither interferon nor PGE-IFN alone, induced type 1 diabetes in a patient with chronic hepatitis C.Intern Med ( 2009) 48(16): 1387-90PMID : 19687584
• Yamaguchi H, Shimizu M, Ban S, Koyama I, Hatori T, Fujita I, Yamamoto M, Kawamura S, Kobayashi M, Ishida K, Morikawa T, Motoi F, Unno M, Kanno A, Satoh K, Shimosegawa T, Orikasa H, Watanabe T, Nishimura K, Ebihara Y, Koike N, Furukawa TIntraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.Am J Surg Pathol ( 2009) 33(8): 1164-72PMID : 19440145
• Shimosegawa T, Kanno AAutoimmune pancreatitis in Japan: overview and perspective.J Gastroenterol ( 2009) 44(6): 503-17PMID : 19377842
• Takagi Y, Masamune A, Kume K, Satoh A, Kikuta K, Watanabe T, Satoh K, Hirota M, Shimosegawa TMicrosatellite polymorphism in intron 2 of human Toll-like receptor 2 gene is associated with susceptibility to acute pancreatitis in Japan.Hum Immunol ( 2009) 70(3): 200-4PMID : 19280717
• Masamune A, Shimosegawa TSignal transduction in pancreatic stellate cells.J Gastroenterol ( 2009) 44(4): 249-60PMID : 19271115
• Kimura H, Miyashita H, Suzuki Y, Kobayashi M, Watanabe K, Sonoda H, Ohta H, Fujiwara T, Shimosegawa T, Sato YDistinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis.Blood ( 2009) 113(19): 4810-8PMID : 19204325
• Kume K, Masamune A, Takagi Y, Kikuta K, Watanabe T, Satoh K, Satoh A, Hirota M, Hamada S, Shimosegawa TA loss-of-function p.G191R variant in the anionic trypsinogen (PRSS2) gene in Japanese patients with pancreatic disorders.Gut ( 2009) 58(6): 820-4PMID : 19052022
• Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Hamada S, Shimosegawa TFibrinogen induces cytokine and collagen production in pancreatic stellate cells.Gut ( 2009) 58(4): 550-9PMID : 19052021
• Hamada S, Satoh K, Hirota M, Fujibuchi W, Kanno A, Umino J, Ito H, Satoh A, Kikuta K, Kume K, Masamune A, Shimosegawa TExpression of the calcium-binding protein S100P is regulated by bone morphogenetic protein in pancreatic duct epithelial cell lines.Cancer Sci ( 2009) 100(1): 103-10PMID : 19018761
• Suzuki N, Masamune A, Kikuta K, Watanabe T, Satoh K, Shimosegawa TEllagic acid inhibits pancreatic fibrosis in male Wistar Bonn/Kobori rats.Dig Dis Sci ( 2009) 54(4): 802-10PMID : 18651219

2008年(10件)

• Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Shimosegawa THypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer.Am J Physiol Gastrointest Liver Physiol ( 2008) 295(4): G709-17PMID : 18669622
• Shinozaki M, Fukudo S, Hongo M, Shimosegawa T, Sasaki D, Matsueda K, Harasawa S, Miura S, Mine T, Kaneko H, Arakawa T, Haruma K, Torii A, Azuma T, Miwa H, Fukunaga M, Handa M, Kitamori S, Miwa THigh prevalence of irritable bowel syndrome in medical outpatients in Japan.J Clin Gastroenterol ( 2008) 42(9): 1010-6PMID : 18607295
• Otsuki M, Chung JB, Okazaki K, Kim MH, Kamisawa T, Kawa S, Park SW, Shimosegawa T, Lee K, Ito T, Nishimori I, Notohara K, Naruse S, Ko SB, Kihara YAsian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis.J Gastroenterol ( 2008) 43(6): 403-8PMID : 18600383
• Masamune A, Kikuta K, Watanabe T, Satoh K, Satoh A, Shimosegawa TPancreatic stellate cells express Toll-like receptors.J Gastroenterol ( 2008) 43(5): 352-62PMID : 18592153
• Satoh K, Kanno A, Hamada S, Hirota M, Umino J, Masamune A, Egawa S, Motoi F, Unno M, Shimosegawa TExpression of Sonic hedgehog signaling pathway correlates with the tumorigenesis of intraductal papillary mucinous neoplasm of the pancreas.Oncol Rep ( 2008) 19(5): 1185-90PMID : 18425375
• Kanno A, Satoh K, Masamune A, Hirota M, Kimura K, Umino J, Hamada S, Satoh A, Egawa S, Motoi F, Unno M, Shimosegawa TPeriostin, secreted from stromal cells, has biphasic effect on cell migration and correlates with the epithelial to mesenchymal transition of human pancreatic cancer cells.Int J Cancer ( 2008) 122(12): 2707-18PMID : 18381746
• Satoh K, Hamada S, Kimura K, Kanno A, Hirota M, Umino J, Fujibuchi W, Masamune A, Tanaka N, Miura K, Egawa S, Motoi F, Unno M, Vonderhaar BK, Shimosegawa TUp-regulation of MSX2 enhances the malignant phenotype and is associated with twist 1 expression in human pancreatic cancer cells.Am J Pathol ( 2008) 172(4): 926-39PMID : 18349132
• Shimosegawa T, Kume K, Masamune ASPINK1, ADH2, and ALDH2 gene variants and alcoholic chronic pancreatitis in Japan.J Gastroenterol Hepatol ( 2008) 23 Suppl 1 S82-6PMID : 18336671
• Masamune A, Watanabe T, Kikuta K, Satoh K, Shimosegawa TNADPH oxidase plays a crucial role in the activation of pancreatic stellate cells.Am J Physiol Gastrointest Liver Physiol ( 2008) 294(1): G99-G108PMID : 17962358
• Shibata C, Funayama Y, Fukushima K, Ueno T, Kohyama A, Satoh K, Shimosegawa T, Yamagiwa T, Sasaki IThe glucagon provocative test for the diagnosis and treatment of Zollinger-Ellison syndrome.J Gastrointest Surg ( 2008) 12(2): 344-9PMID : 17929104

肝臓グループ

2025年(9件)

• Onuki M, Inoue J, Doi K, Ninomiya M, Sano A, Tsuruoka M, Sato K, Sawahashi S, Ouchi K, Watanabe K, McNiven MA, Masamune AThe interferon-inducible MxB large GTPase attenuates hepatitis B virus replication by activating the RIG-I innate immunity signaling pathway.Sci Rep ( 2025) 15(1): 44008PMID : 41407770
• Ninomiya M, Tsuruoka M, Inoue J, Hiraoka A, Sano A, Sato K, Onuki M, Sawahashi S, Ouchi K, Watanabe K, Kuroda H, Oikawa T, Abe T, Fujita M, Abe K, Katsumi T, Sato W, Igarashi G, Iino C, Tanabe N, Numao H, Ohira H, Ueno Y, Masamune AA New Model to Predict Survival Time in Patients With Hepatocellular Carcinoma With BCLC Advanced Stage.Cancer Med ( 2025) 14(20): e71299PMID : 41090669
• Tsuruoka M, Ninomiya M, Inoue J, Sato K, Ouchi K, Watanabe K, Doi K, Sasazaki T, Masamune AGiant hepatic hemangioma in a Japanese adult patient reduced by sirolimus therapy.Clin J Gastroenterol ( 2025) 18(5): 918-924PMID : 40748519
• Sato K, Inoue J, Ninomiya M, Sano A, Tsuruoka M, Onuki M, Sawahashi S, Ouchi K, Doi K, Watanabe K, Masamune AIdentification of low-molecular compounds that inhibit envelope formation of hepatitis B virus.Sci Rep ( 2025) 15(1): 24344PMID : 40624334
• Sato K, Inoue J, Akahane T, Kobayashi T, Ninomiya M, Sano A, Tsuruoka M, Onuki M, Sawahashi S, Ouchi K, Doi K, Watanabe K, Niitsuma H, Masamune AComparison of hepatitis B virus genotype B and C patients in Japan in terms of family history and maternal age at birth.Hepatol Res ( 2025) 55(5): 773-779PMID : 40317570
• Kobayashi T, Inoue J, Tanaka Y, Yamakawa M, Kurihara M, Handa T, Kondo Y, Saitou A, Shiraki M, Kojima Y, Ohyauchi M, Masamune AHypozincemia Is Associated With Increased Tyrosine Levels, Low Handgrip Strength, Increased Incidence of HCC, and Liver Disease Progression-A Cross-Sectional Study.JGH Open ( 2025) 9(3): e70124PMID : 40109879
• Inoue J, Minami S, Abe K, Kida M, Haga H, Iino C, Numao H, Kuroda H, Ninomiya M, Tsuruoka M, Sato K, Onuki M, Sawahashi S, Ouchi K, Watanabe K, Akahane T, Kobayashi T, Ohira H, Ueno Y, Masamune AValidation Study of Scores Predicting Hepatocellular Carcinoma Risk in Chronic Hepatitis B Patients Treated With Nucleos(t)ide Analogues.J Viral Hepat ( 2025) 32(4): e70021PMID : 40052685
• Inoue J, Akahane T, Miyazaki Y, Ninomiya M, Sano A, Tsuruoka M, Sato K, Onuki M, Sawahashi S, Ouchi K, Masamune ALong-read deep sequencing analysis of hepatitis B virus quasispecies in two elderly cases of interspousal transmission.J Infect Chemother ( 2025) 31(1): 102521PMID : 39270848
• Sano A, Sasaki M, Inoue J, Kakazu E, Ninomiya M, Tsuruoka M, Sato K, Onuki M, Sawahashi S, Ouchi K, Doi K, Katori Y, Masamune AType 2 Diabetes Mellitus Is a Risk Factor for Skeletal Muscle Loss in the Course of Dietary Treatment for Patients with Metabolic Dysfunction-associated Steatotic Liver Disease.Intern Med ( 2025) 64(5): 631-641PMID : 39048367

2024年(10件)

• Mino M, Kakazu E, Sano A, Tsuruoka M, Matsubara H, Kakisaka K, Kogure T, Sekine K, Aoki Y, Imamura M, Matsuda M, Yamazoe T, Mori T, Yoshio S, Inoue J, Masamune A, Kanto TComprehensive analysis of peripheral blood free amino acids in MASLD: the impact of glycine-serine-threonine metabolism.Amino Acids ( 2024) 57(1): 3PMID : 39718621
• Yamauchi M, Maekawa M, Sato T, Sato Y, Kumondai M, Tsuruoka M, Inoue J, Masamune A, Mano NLiquid Chromatography/Tandem Mass Spectrometry-Based Simultaneous Analysis of 32 Bile Acids in Plasma and Conventional Biomarker-Integrated Diagnostic Screening Model Development for Hepatocellular Carcinoma.Metabolites ( 2024) 14(9):PMID : 39330520
• Doi K, Inoue J, Ninomiya M, Sano A, Tsuruoka M, Sato K, Onuki M, Sawahashi S, Ouchi K, Masamune AThree consecutive cases of acute liver failure in young women due to acetaminophen overdose: insights into Japanese social issues and transplantation landscape.Clin J Gastroenterol ( 2024) 17(5): 948-954PMID : 39060756
• Tsuruoka M, Ninomiya M, Inoue J, Iwata T, Sano A, Sato K, Onuki M, Sawahashi S, Masamune AChanges in Mutations of Cell-Free DNA and Liver Tumor Tissue in Patients with Advanced Hepatocellular Carcinoma before and after Introduction of Lenvatinib.Oncology ( 2024) 102(12): 1072-1083PMID : 39047713
• Sano A, Inoue J, Kakazu E, Ninomiya M, Tsuruoka M, Sato K, Onuki M, Sawahashi S, Ouchi K, Masamune AAssociation of Omega-3 Polyunsaturated Fatty Acids with Sarcopenia in Liver Cirrhosis Patients with Hepatocellular Carcinoma.J Clin Transl Hepatol ( 2024) 12(7): 613-624PMID : 38993515
• Kanda T, Li TC, Takahashi M, Nagashima S, Primadharsini PP, Kunita S, Sasaki-Tanaka R, Inoue J, Tsuchiya A, Nakamoto S, Abe R, Fujiwara K, Yokosuka O, Suzuki R, Ishii K, Yotsuyanagi H, Okamoto HRecent advances in hepatitis E virus research and the Japanese clinical practice guidelines for hepatitis E virus infection.Hepatol Res ( 2024) PMID : 38874115
• Enomoto H, Akuta N, Hikita H, Suda G, Inoue J, Tamaki N, Ito K, Akahane T, Kawaoka T, Morishita A, Ogawa E, Tateishi R, Yoshiji HEtiological changes of liver cirrhosis and hepatocellular carcinoma-complicated liver cirrhosis in Japan: Updated nationwide survey from 2018 to 2021.Hepatol Res ( 2024) PMID : 38638067
• Mino M, Sano A, Kakazu E, Matsubara H, Kakisaka K, Kogure T, Sekine K, Aoki Y, Imamura M, Matsuda M, Yamazoe T, Mori T, Yoshio S, Inoue J, Masamune A, Kanto TDifferences in branched-chain amino acid to tyrosine ratio (BTR) among etiologies of chronic liver disease progression compared to healthy adults.J Gastroenterol ( 2024) PMID : 38530472
• Ouchi K, Okamoto H, Inoue J, Kobayashi S, Nagai H, Okamoto D, Manaka T, Nozawa Y, Masamune AAcute Liver Injury and Bilateral Pulmonary Artery Thrombosis Due to Hypereosinophilic Syndrome.Intern Med ( 2024) 63(17): 2415-2420PMID : 38296476
• Kanda T, Sasaki-Tanaka R, Ishii K, Suzuki R, Inoue J, Tsuchiya A, Nakamoto S, Abe R, Fujiwara K, Yokosuka O, Li TC, Kunita S, Yotsuyanagi H, Okamoto HRecent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan.Hepatol Res ( 2024) 54(1): 4-23PMID : 37906585

2023年(9件)

• Ninomiya M, Tsuruoka M, Inoue J, Hiraoka A, Iwata T, Sano A, Sato K, Onuki M, Sawahashi S, Kuroda H, Oikawa T, Fujita M, Abe K, Katsumi T, Sato W, Igarashi G, Iino C, Endo T, Tanabe N, Numao H, Iijima K, Matsumoto T, Ohira H, Ueno Y, Masamune AA new model to estimate duration of survival in patients with hepatocellular carcinoma with BCLC intermediate stage.Sci Rep ( 2023) 13(1): 20739PMID : 38007597
• Shirota S, Shirai T, Mori K, Inoue J, Sato H, Ishii T, Fujii HComment on: A case of vanishing bile duct syndrome during treatment of microscopic polyangiitis with avacopan.Rheumatology (Oxford) ( 2023) PMID : 37878792
• Jiang C, Saiki Y, Hirota S, Iwata K, Wang X, Ito Y, Murakami K, Imura T, Inoue J, Masamune A, Hirayama A, Goto M, Furukawa TAblation of dual specificity phosphatase 6 protects against non-alcoholic fatty liver disease via CYP4A and MAPK.Am J Pathol ( 2023) PMID : 37741451
• Tsuruoka M, Inoue J, Ninomiya M, Iwata T, Sano A, Sato K, Onuki M, Sawahashi S, Masamune A[Achieving diversity in the medical field:a survey of female physicians and medical staff in the Department of Gastroenterology].Nihon Shokakibyo Gakkai Zasshi ( 2023) 120(9): 746-754PMID : 37690830
• Inoue J, Akahane T, Kobayashi T, Kimura O, Sato K, Ninomiya M, Iwata T, Takai S, Kisara N, Sato T, Nagasaki F, Miura M, Nakamura T, Umetsu T, Sano A, Tsuruoka M, Onuki M, Sawahashi S, Niitsuma H, Masamune AUsefulness of FIB-4 index and ALT at 1 year of nucleos(t)ide analog treatment for prediction of hepatocellular carcinoma in chronic hepatitis B patients.Hepatol Res ( 2023) PMID : 37621201
• Sato K, Inoue J, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Onuki M, Sawahashi S, Ouchi K, Masamune AEffectiveness of tacrolimus in a case of immune checkpoint inhibitor-induced hepatotoxicity that was refractory to steroids and mycophenolate mofetil.Clin J Gastroenterol ( 2023) PMID : 37480423
• Mino M, Kakazu E, Sano A, Katsuyama H, Hakoshima M, Yanai H, Aoki Y, Imamura M, Yamazoe T, Mori T, Yoshio S, Inoue J, Masamune A, Kanto TEffects of sodium glucose cotransporter 2 inhibitors and pioglitazone on FIB-4 index in metabolic-associated fatty liver disease.Hepatol Res ( 2023) 53(7): 618-628PMID : 36905232
• Tsuruoka M, Inoue J, Ouchi K, Uno K, Itami H, Ninomiya M, Iwata T, Sano A, Sato K, Onuki M, Sawahashi S, Koike T, Masamune ADuodenal Variceal Rupture during Atezolizumab and Bevacizumab Treatment for Hepatocellular Carcinoma.Intern Med ( 2023) 62(10): 1467-1472PMID : 36198602
• Machida T, Obara T, Ishikuro M, Murakami K, Ueno F, Noda A, Onuma T, Matsuzaki F, Inoue J, Kuriyama S, Mano NLiver steatosis and fibrosis markers' association with cardiovascular and renal damage in Japanese adults: the TMM BirThree cohort study.Ann Hepatol ( 2023) 28(1): 100761PMID : 36179796

2022年(7件)

• Sato K, Inoue J, Akahane T, Kobayashi T, Takai S, Nakamura T, Sato T, Kimura O, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Onuki M, Sawahashi S, Niitsuma H, Masamune ASwitching to Tenofovir Alafenamide Fumarate in Chronic Hepatitis B Patients Who Had Detectable HBV DNA during Treatment with Entecavir.Tohoku J Exp Med ( 2022) PMID : 36244758
• Sato K, Inoue J, Akahane T, Kobayashi T, Sato S, Kisara N, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Onuki M, Masamune ASwitching to tenofovir alafenamide versus continued therapy in chronic hepatitis B patients who were treated with entecavir: A prospective, multicenter, randomized controlled study.Medicine (Baltimore) ( 2022) 101(39): e30630PMID : 36181074
• Sakamoto K, Ito K, Yotsuyanagi H, Yatsuhashi H, Tanaka Y, Hige S, Takikawa Y, Ueno Y, Yamamoto K, Imazeki F, Inoue J, Kurosaki M, Umemura T, Toyoda H, Mita E, Michitaka K, Maeshiro T, Yamada N, Suetsugu A, Kawanaka M, Seko Y, Matsuura K, Okumura A, Fukuzawa Y, Sugiyama M, Mizokami M, Yoneda MTrends of hepatitis B virus genotype distribution in chronic hepatitis B patients in Japan.J Gastroenterol ( 2022) PMID : 36173513
• Kuroda H, Oikawa T, Ninomiya M, Fujita M, Abe K, Okumoto K, Katsumi T, Sato W, Igarashi G, Iino C, Endo T, Tanabe N, Numao H, Fukuda S, Iijima K, Masamune A, Ohira H, Ueno Y, Takikawa YObjective Response by mRECIST to Initial Lenvatinib Therapy Is an Independent Factor Contributing to Deep Response in Hepatocellular Carcinoma Treated with Lenvatinib-Transcatheter Arterial Chemoembolization Sequential Therapy.Liver Cancer ( 2022) 11(4): 383-396PMID : 35978602
• Saito A, Kikuchi M, Matsumoto Y, Sugawara E, Takao G, Inomata H, Takahashi A, Sato Y, Kumondai M, Sato Y, Sato T, Ninomiya M, Inoue J, Maekawa M, Mano NEvaluation of a Capillary Microsampling Device for Analyzing Plasma Lenvatinib Concentration in Patients with Hepatocellular Carcinoma.Ther Drug Monit ( 2022) PMID : 35863065
• Inoue J, Kobayashi T, Akahane T, Kimura O, Sato K, Ninomiya M, Iwata T, Takai S, Kisara N, Sato T, Nagasaki F, Miura M, Nakamura T, Umetsu T, Sano A, Tsuruoka M, Onuki M, Niitsuma H, Masamune A, Therme Study GroupNon-Achievement of Alanine Aminotransferase Normalization Associated with the Risk of Hepatocellular Carcinoma during Nucleos(t)ide Analogue Therapies: A Multicenter Retrospective Study.J Clin Med ( 2022) 11(9):PMID : 35566481
• Machida T, Obara T, Miyazaki M, Inoue J, Mano NTrends in drug prescriptions for type 2 diabetes, hypertension, and dyslipidemia among adults with non-alcoholic fatty liver disease.Ann Hepatol ( 2022) 100699PMID : 35278680

2021年(9件)

• Ninomiya M, Inoue J, Krueger EW, Chen J, Cao H, Masamune A, McNiven MAThe Exosome-Associated Tetraspanin CD63 Contributes to the Efficient Assembly and Infectivity of the Hepatitis B Virus.Hepatol Commun ( 2021) 5(7): 1238-1251PMID : 34278172
• Inoue J, Sato K, Ninomiya M, Masamune AEnvelope Proteins of Hepatitis B Virus: Molecular Biology and Involvement in Carcinogenesis.Viruses ( 2021) 13(6):PMID : 34208172
• Sato K, Inoue J, Kakazu E, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Masamune AReactivation of hepatitis C virus with severe hepatitis flare during steroid administration for interstitial pneumonia.Clin J Gastroenterol ( 2021) 14(4): 1221-1226PMID : 33983567
• Sano A, Tsuge S, Kakazu E, Iwata T, Ninomiya M, Tsuruoka M, Inoue J, Masamune APlasma free amino acids are associated with sarcopenia in the course of hepatocellular carcinoma recurrence.Nutrition ( 2021) 84 111007PMID : 33745507
• Sano A, Kakazu E, Hamada S, Inoue J, Ninomiya M, Iwata T, Tsuruoka M, Sato K, Masamune ASteatotic hepatocytes release mature VLDL via methionine and tyrosine metabolism in a Keap1-Nrf2 dependent manner.Hepatology ( 2021) PMID : 33724516
• Tsuruoka M, Inoue J, Onishi Y, Ninomiya M, Kakazu E, Iwata T, Sano A, Sato K, Harigae H, Masamune AHepatitis B Virus Reactivation with Discontinuation of Nucleoside Analogue in Patients Who Received Allogeneic Hematopoietic Stem Cell Transplantation.Case Rep Gastroenterol ( 2021) 15(1): 178-187PMID : 33708067
• Onodera K, Onishi Y, Inoue J, Tanaka Y, Yonha L, Ichikawa S, Fukuhara N, Yokoyama H, Murai K, Masamune A, Harigae HSecond direct-acting antiviral therapy for hepatitis C virus infection after umbilical cord blood transplantation: A case report.J Infect Chemother ( 2021) 27(8): 1230-1233PMID : 33589371
• Hidaka I, Enomoto M, Sato S, Suetsugu A, Matono T, Ito K, Ogawa K, Inoue J, Horino M, Kondo Y, Sakaida I, Korenaga MEstablishing Efficient Systems through Electronic Medical Records to Promote Intra-hospital Referrals of Hepatitis Virus Carriers to Hepatology Specialists: A Multicenter Questionnaire-based Survey of 1,281 Healthcare Professionals.Intern Med ( 2021) 60(3): 337-343PMID : 33518608
• Inoue J, Akahane T, Kobayashi T, Obara N, Umetsu T, Kakazu E, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Sato K, Masamune ASwitching to tenofovir disoproxil fumarate in entecavir-treated chronic hepatitis B patients: A pilot randomized controlled study.Biomed Rep ( 2021) 14(2): 20PMID : 33335726

2020年(7件)

• Shoji T, Kanamori M, Inoue J, Saito R, Osada Y, Shimoda Y, Chonan M, Uenohara H, Masamune A, Tominaga THepatitis B virus reactivation during temozolomide administration for malignant glioma.Int J Clin Oncol ( 2020) PMID : 33118116
• Itakura J, Kurosaki M, Kakizaki S, Amano K, Nakayama N, Inoue J, Endo T, Marusawa H, Hasebe C, Joko K, Wada S, Akahane T, Koushima Y, Ogawa C, Kanto T, Mizokami M, Izumi NFeatures of resistance-associated substitutions after failure of multiple direct-acting antiviral regimens for hepatitis C.JHEP Rep ( 2020) 2(5): 100138PMID : 32817930
• Iwata T, Inoue J, Kakazu E, Ninomiya M, Sano A, Tsuruoka M, Kume K, Masamune ARapid enlargement of a hepatic hilar cyst leading to bile duct obstruction after acute exacerbation of chronic hepatitis B.Clin J Gastroenterol ( 2020) PMID : 32729100
• Tsuruoka M, Inoue J, Kakazu E, Ninomiya M, Iwata T, Sano A, Masamune AMethotrexate-associated Lymphoproliferative Disorder in the Liver Resembling Hepatocellular Carcinoma Treated with Transarterial Chemoembolization.Intern Med ( 2020) PMID : 32522926
• Obara N, Inoue J, Endo H, Kakazu E, Ninomiya M, Iwata T, Sano A, Tsuruoka M, Masamune ASpontaneous reactivation of hepatitis B virus with S gene mutations in an elderly patient with diabetic nephropathy.Clin J Gastroenterol ( 2020) PMID : 32519312
• Yagi M, Matsumoto K, Komori A, Abe M, Hashimoto N, Inao M, Namisaki T, Kawata K, Ninomiya M, Fujii H, Takahashi A, Kang JH, Takamura M, Arakawa M, Joshita S, Sato K, Itakura J, Nomura T, Kakisaka K, Kaneko A, Tamura Y, Miura R, Aiso M, Arizumi T, Asaoka Y, Kikuchi K, Takikawa Y, Masaki T, Umemura T, Honda A, Ohira H, Kawada N, Yoshiji H, Mochida S, Takikawa H, Tanaka AA validation study of the Ursodeoxycholic Acid Response Score in Japanese patients with primary biliary cholangitis.Liver Int ( 2020) PMID : 32438508
• Nakamura T, Inoue J, Ninomiya M, Kakazu E, Iwata T, Takai S, Sano A, Kogure T, Shimosegawa T, Masamune AEffect of viral DNA methylation on expression of hepatitis B virus proteins depends on the virus genotype.Virus Genes ( 2020) PMID : 32361814

2019年(8件)

• Kondo Y, Kogure T, Ninomiya M, Fukuda R, Monma N, Ikeo K, Tanaka YThe reduction of miR146b-5p in monocytes and T cells could contribute to the immunopathogenesis of hepatitis C virus infection.Sci Rep ( 2019) 9(1): 13393PMID : 31527804
• Inoue J, Akahane T, Nakayama H, Kimura O, Kobayashi T, Kisara N, Sato T, Morosawa T, Izuma M, Kakazu E, Ninomiya M, Iwata T, Takai S, Nakamura T, Sano A, Niitsuma H, Masamune AComparison of hepatitis B virus genotypes B and C among chronically hepatitis B virus-infected patients who received nucleos(t)ide analogs: A multicenter retrospective study.Hepatol Res ( 2019) 49(11): 1263-1274PMID : 31254482
• Inoue J, Ninomiya M, Umetsu T, Nakamura T, Kogure T, Kakazu E, Iwata T, Takai S, Sano A, Fukuda M, Watashi K, Isogawa M, Tanaka Y, Shimosegawa T, McNiven MA, Masamune ASmall Interfering RNA Screening for the Small GTPase Rab Proteins Identifies Rab5B as a Major Regulator of Hepatitis B Virus Production.J Virol ( 2019) 93(15): e00621-19PMID : 31118260
• Inoue J, Nakamura T, Masamune ARoles of Hepatitis B Virus Mutations in the Viral Reactivation after Immunosuppression Therapies.Viruses ( 2019) 11(5): E457PMID : 31109119
• Sano A, Inoue J, Kakazu E, Ninomiya M, Iwata T, Morosawa T, Takai S, Nakamura T, Masamune AAcute-onset Autoimmune Hepatitis in a Patient with Selective Immunoglobulin M Deficiency.Intern Med ( 2019) 58(15): 2185-2190PMID : 30996186
• Kakazu E, Sano A, Morosawa T, Inoue J, Ninomiya M, Iwata T, Nakamura T, Takai S, Sawada S, Katagiri H, Shimosegawa T, Masamune ABranched chain amino acids are associated with the heterogeneity of the area of lipid droplets in hepatocytes of patients with non-alcoholic fatty liver disease.Hepatol Res ( 2019) 49(8): 860-871PMID : 30972908
• Suda G, Hasebe C, Abe M, Kurosaki M, Itakura J, Izumi N, Uchida Y, Mochida S, Haga H, Ueno Y, Abe K, Takahashi A, Ohira H, Tsukuda Y, Furuya K, Baba M, Yamamoto Y, Kobayashi T, Inoue J, Terasita K, Ohara M, Kawagishi N, Izumi T, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto NSafety and efficacy of glecaprevir and pibrentasvir in Japanese hemodialysis patients with genotype 2 hepatitis C virus infection.J Gastroenterol ( 2019) 54(7): 641-649PMID : 30778716
• Honda A, Tanaka A, Kaneko T, Komori A, Abe M, Inao M, Namisaki T, Hashimoto N, Kawata K, Takahashi A, Ninomiya M, Kang JH, Arakawa M, Yamagiwa S, Joshita S, Umemura T, Sato K, Kaneko A, Kikuchi K, Itakura J, Nomura T, Kakisaka K, Fujii H, Kawada N, Takikawa Y, Masaki T, Ohira H, Mochida S, Yoshiji H, Iimuro S, Matsuzaki Y, Takikawa HBezafibrate Improves GLOBE and UK-PBC Scores and Long-Term Outcomes in Patients With Primary Biliary Cholangitis.Hepatology ( 2019) 70(6): 2035-2046PMID : 30737815

2018年(7件)

• Fukushima M, Dasgupta D, Mauer AS, Kakazu E, Nakao K, Malhi HStAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.J Biol Chem ( 2018) 293(39): 15277-15289PMID : 30139741
• Umetsu T, Inoue J, Kogure T, Kakazu E, Ninomiya M, Iwata T, Takai S, Nakamura T, Sano A, Shimosegawa TInhibitory effect of silibinin on hepatitis B virus entry.Biochem Biophys Rep ( 2018) 14 20-25PMID : 29872730
• Honma M, Sawada S, Ueno Y, Murakami K, Yamada T, Gao J, Kodama S, Izumi T, Takahashi K, Tsukita S, Uno K, Imai J, Kakazu E, Kondo Y, Mizuno K, Kawagishi N, Shimosegawa T, Katagiri HSelective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers.Int J Obes (Lond) ( 2018) 42(9): 1544-1555PMID : 29717275
• Fujisaka Y, Iwata T, Tamai K, Nakamura M, Mochizuki M, Shibuya R, Yamaguchi K, Shimosegawa T, Satoh KLong non-coding RNA HOTAIR up-regulates chemokine (C-C motif) ligand 2 and promotes proliferation of macrophages and myeloid-derived suppressor cells in hepatocellular carcinoma cell lines.Oncol Lett ( 2018) 15(1): 509-514PMID : 29387231
• Sano A, Kakazu E, Morosawa T, Inoue J, Kogure T, Ninomiya M, Iwata T, Umetsu T, Nakamura T, Takai S, Shimosegawa TThe profiling of plasma free amino acids and the relationship between serum albumin and plasma-branched chain amino acids in chronic liver disease: a single-center retrospective study.J Gastroenterol ( 2018) 53(8): 978-988PMID : 29380062
• Inoue J, Ninomiya M, Shimosegawa T, McNiven MACellular Membrane Trafficking Machineries Used by the Hepatitis Viruses.Hepatology ( 2018) 68(2): 751-762PMID : 29331069
• Takai S, Inoue J, Kogure T, Kakazu E, Ninomiya M, Iwata T, Umetsu T, Nakamura T, Sano A, Shimosegawa TAcute-onset Autoimmune Hepatitis in a Young Woman with Type 1 Diabetes Mellitus.Intern Med ( 2018) 57(11): 1591-1596PMID : 29321432

2017年(5件)

• Kogure T, Inoue J, Kakazu E, Ninomiya M, Shimosegawa TGastroesophageal Variceal Bleeding Successfully Controlled by Partial Splenic Embolization.Intern Med ( 2017) 56(11): 1339-1343PMID : 28566595
• Matsuura K, Sawai H, Ikeo K, Ogawa S, Iio E, Isogawa M, Shimada N, Komori A, Toyoda H, Kumada T, Namisaki T, Yoshiji H, Sakamoto N, Nakagawa M, Asahina Y, Kurosaki M, Izumi N, Enomoto N, Kusakabe A, Kajiwara E, Itoh Y, Ide T, Tamori A, Matsubara M, Kawada N, Shirabe K, Tomita E, Honda M, Kaneko S, Nishina S, Suetsugu A, Hiasa Y, Watanabe H, Genda T, Sakaida I, Nishiguchi S, Takaguchi K, Tanaka E, Sugihara J, Shimada M, Kondo Y, Kawai Y, Kojima K, Nagasaki M, Tokunaga K, Tanaka YGenome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.Gastroenterology ( 2017) 152(6): 1383-1394PMID : 28163062
• Asai Y, Yamada T, Tsukita S, Takahashi K, Maekawa M, Honma M, Ikeda M, Murakami K, Munakata Y, Shirai Y, Kodama S, Sugisawa T, Chiba Y, Kondo Y, Kaneko K, Uno K, Sawada S, Imai J, Nakamura Y, Yamaguchi H, Tanaka K, Sasano H, Mano N, Ueno Y, Shimosegawa T, Katagiri HActivation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.Gastroenterology ( 2017) 152(6): 1521-1535.e8PMID : 28088462
• Inoue J, Kanno A, Wakui Y, Miura M, Kobayashi T, Morosawa T, Kogure T, Kakazu E, Ninomiya M, Fujisaka Y, Umetsu T, Takai S, Nakamura T, Shimosegawa TIdentification of Genotype 2 HCV in Serotype-1 Hepatitis C Patients Unresponsive to Daclatasvir plus Asunaprevir Treatment.Tohoku J Exp Med ( 2017) 241(1): 21-28PMID : 28049871
• Miura M, Inoue J, Tsuruoka M, Nishizawa T, Nagashima S, Takahashi M, Shimosegawa T, Okamoto HFull-length genomic sequence analysis of new subtype 3k hepatitis E virus isolates with 99.97% nucleotide identity obtained from two consecutive acute hepatitis patients in a city in northeast Japan.J Med Virol ( 2017) 89(6): 1116-1120PMID : 27922191

2016年(5件)

• Iwata T, Kondo Y, Kimura O, Morosawa T, Fujisaka Y, Umetsu T, Kogure T, Inoue J, Nakagome Y, Shimosegawa TPD-L1⁺MDSCs are increased in HCC patients and induced by soluble factor in the tumor microenvironment.Sci Rep ( 2016) 6 39296PMID : 27966626
• Katsumi T, Ninomiya M, Nishina T, Mizuno K, Tomita K, Haga H, Okumoto K, Saito T, Shimosegawa T, Ueno YMiR-139-5p is associated with inflammatory regulation through c-FOS suppression, and contributes to the progression of primary biliary cholangitis.Lab Invest ( 2016) 96(11): 1165-1177PMID : 27668889
• Ninomiya M, Kondo Y, Kimura O, Funayama R, Nagashima T, Kogure T, Morosawa T, Tanaka Y, Nakayama K, Shimosegawa TThe expression of miR-125b-5p is increased in the serum of patients with chronic hepatitis B infection and inhibits the detection of hepatitis B virus surface antigen.J Viral Hepat ( 2016) 23(5): 330-9PMID : 26924666
• Inoue J, Kondo Y, Wakui Y, Kogure T, Morosawa T, Fujisaka Y, Umetsu T, Takai S, Nakamura T, Shimosegawa TReactivation of resolved hepatitis B virus infection with immune escape mutations after long-term corticosteroid therapy.Clin J Gastroenterol ( 2016) 9(2): 93-8PMID : 26919858
• Inoue J, Kondo Y, Umetsu T, Yamamoto T, Miura M, Mano Y, Kobayashi T, Obara N, Niitsuma H, Kogure T, Nakagome Y, Kimura O, Iwata T, Morosawa T, Fujisaka Y, Shimosegawa TShifting hepatitis B virus genotypes of acute hepatitis B patients in northeast Japan.J Med Virol ( 2016) 88(1): 69-78PMID : 26113372

2015年(7件)

• Kondo Y, Kimura O, Kogure T, Ninomiya M, Umezawa R, Sugawara T, Matsushita H, Jingu K, Nakagome Y, Iwata T, Morosawa T, Fujisaka Y, Iwasaki T, Shimosegawa TRadiation Therapy Is a Reasonable Option for Improving the Prognosis in Hepatocellular Carcinoma.Tohoku J Exp Med ( 2015) 237(4): 249-57PMID : 26560989
• Shimada M, Okawa H, Kondo Y, Maejima T, Kataoka Y, Hisamichi K, Maekawa M, Matsuura M, Jin Y, Mori M, Suzuki H, Shimosegawa T, Mano NMonitoring Serum Levels of Sorafenib and Its N-Oxide Is Essential for Long-Term Sorafenib Treatment of Patients with Hepatocellular Carcinoma.Tohoku J Exp Med ( 2015) 237(3): 173-82PMID : 26477611
• Kondo Y, Kimura O, Tanaka Y, Ninomiya M, Iwata T, Kogure T, Inoue J, Sugiyama M, Morosawa T, Fujisaka Y, Shimosegawa TDifferential Expression of CX3CL1 in Hepatitis B Virus-Replicating Hepatoma Cells Can Affect the Migration Activity of CX3CR1+ Immune Cells.J Virol ( 2015) 89(14): 7016-27PMID : 25926643
• Kondo Y, Kimura O, Shimosegawa TSignificant biomarkers for the management of hepatocellular carcinoma.Clin J Gastroenterol ( 2015) 8(3): 109-15PMID : 25855582
• Inoue J, Krueger EW, Chen J, Cao H, Ninomiya M, McNiven MAHBV secretion is regulated through the activation of endocytic and autophagic compartments mediated by Rab7 stimulation.J Cell Sci ( 2015) 128(9): 1696-706PMID : 25770103
• Kondo Y, Shimosegawa TSignificant roles of regulatory T cells and myeloid derived suppressor cells in hepatitis B virus persistent infection and hepatitis B virus-related HCCs.Int J Mol Sci ( 2015) 16(2): 3307-22PMID : 25654227
• Kondo Y, Kimura O, Shimosegawa TRadiation therapy has been shown to be adaptable for various stages of hepatocellular carcinoma.World J Gastroenterol ( 2015) 21(1): 94-101PMID : 25574082

2014年(12件)

• Takahashi K, Yan IK, Kogure T, Haga H, Patel TExtracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer.FEBS Open Bio ( 2014) 4 458-67PMID : 24918061
• Kondo Y, Ninomiya M, Kimura O, Machida K, Funayama R, Nagashima T, Kobayashi K, Kakazu E, Kato T, Nakayama K, Lai MM, Shimosegawa THCV infection enhances Th17 commitment, which could affect the pathogenesis of autoimmune diseases.PLoS One ( 2014) 9(6): e98521PMID : 24905921
• Shimada M, Okawa H, Maejima T, Yanagi T, Hisamichi K, Matsuura M, Akasaka K, Tsuchiya M, Kondo Y, Shimosegawa T, Mori M, Maekawa M, Suzuki H, Mano NA quantitative HPLC-UV method for determination of serum sorafenib and sorafenib N-oxide and its application in hepatocarcinoma patients.Tohoku J Exp Med ( 2014) 233(2): 103-12PMID : 24872323
• Kimura O, Kondo Y, Kogure T, Kakazu E, Ninomiya M, Iwata T, Morosawa T, Shimosegawa TExpression of EpCAM increases in the hepatitis B related and the treatment-resistant hepatocellular carcinoma.Biomed Res Int ( 2014) 2014 172913PMID : 24696843
• Hori T, Uemoto S, Chen F, Gardner LB, Baine AM, Hata T, Kogure T, Nguyen JHOxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats.World J Hepatol ( 2014) 6(2): 72-84PMID : 24575166
• Ninomiya M, Ueno Y, Shimosegawa TApplication of deep sequence technology in hepatology.Hepatol Res ( 2014) 44(2): 141-8PMID : 23905712
• Kogure T, Kondo Y, Kakazu E, Ninomiya M, Kimura O, Shimosegawa TInvolvement of miRNA-29a in epigenetic regulation of transforming growth factor-β-induced epithelial-mesenchymal transition in hepatocellular carcinoma.Hepatol Res ( 2014) 44(8): 907-19PMID : 23789939
• Hori T, Ogura Y, Yagi S, Iida T, Taniguchi K, El Moghazy WM, Hedaya MS, Segawa H, Ogawa K, Kogure T, Uemoto SHow do transplant surgeons accomplish optimal portal venous flow during living-donor liver transplantation? Noninvasive measurement of indocyanine green elimination rate.Surg Innov ( 2014) 21(1): 43-51PMID : 23703675
• Kogure T, Kondo Y, Kakazu E, Ninomiya M, Kimura O, Kobayashi N, Shimosegawa TThree cases of adult-onset type II citrullinemia treated with different therapies: Efficacy of sodium pyruvate and low-carbohydrate diet.Hepatol Res ( 2014) 44(6): 707-12PMID : 23701493
• Ninomiya M, Kondo Y, Niihori T, Nagashima T, Kogure T, Kakazu E, Kimura O, Aoki Y, Matsubara Y, Shimosegawa TSequential analysis of amino acid substitutions with hepatitis B virus in association with nucleoside/nucleotide analog treatment detected by deep sequencing.Hepatol Res ( 2014) 44(6): 678-84PMID : 23701433
• Hori T, Uemoto S, Walden LB, Chen F, Baine AM, Hata T, Kogure T, Nguyen JHMatrix metalloproteinase-9 as a therapeutic target for the progression of fulminant liver failure with hepatic encephalopathy: A pilot study in mice.Hepatol Res ( 2014) 44(6): 651-62PMID : 23672352
• Kondo Y, Iwata T, Haga T, Kimura O, Ninomiya M, Kakazu E, Kogure T, Morosawa T, Aiba S, Shimosegawa TEradication of hepatitis C virus could improve immunological status and pyoderma gangrenosum-like lesions.Hepatol Res ( 2014) 44(2): 238-45PMID : 23551965

2013年(11件)

• Kakazu E, Kondo Y, Ninomiya M, Kimura O, Nagasaki F, Ueno Y, Shimosegawa TThe influence of pioglitazone on the plasma amino acid profile in patients with nonalcoholic steatohepatitis (NASH).Hepatol Int ( 2013) 7(2): 577-85PMID : 26201790
• Kakazu E, Kondo Y, Kogure T, Ninomiya M, Kimura O, Ueno Y, Shimosegawa TPlasma amino acids imbalance in cirrhotic patients disturbs the tricarboxylic acid cycle of dendritic cell.Sci Rep ( 2013) 3 3459PMID : 24322372
• Kondo Y, Shimosegawa TDirect effects of hepatitis C virus on the lymphoid cells.World J Gastroenterol ( 2013) 19(44): 7889-95PMID : 24307783
• Kogure T, Yan IK, Lin WL, Patel TExtracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular Cancer.Genes Cancer ( 2013) 4(7-8): 261-72PMID : 24167654
• Kogure T, Kinghorn AD, Yan I, Bolon B, Lucas DM, Grever MR, Patel TTherapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer.PLoS One ( 2013) 8(9): e76136PMID : 24086701
• Kakazu E, Kondo Y, Kogure T, Ninomiya M, Kimura O, Iwata T, Morosawa T, Iwasaki T, Shimosegawa TSupplementation of branched-chain amino acids maintains the serum albumin level in the course of hepatocellular carcinoma recurrence.Tohoku J Exp Med ( 2013) 230(4): 191-6PMID : 23892757
• Ninomiya M, Kondo Y, Funayama R, Nagashima T, Kogure T, Kakazu E, Kimura O, Ueno Y, Nakayama K, Shimosegawa TDistinct microRNAs expression profile in primary biliary cirrhosis and evaluation of miR 505-3p and miR197-3p as novel biomarkers.PLoS One ( 2013) 8(6): e66086PMID : 23776611
• Kogure T, Patel TIsolation of extracellular nanovesicle microRNA from liver cancer cells in culture.Methods Mol Biol ( 2013) 1024 11-8PMID : 23719939
• Kondo Y, Kato T, Kimura O, Iwata T, Ninomiya M, Kakazu E, Miura M, Akahane T, Miyazaki Y, Kobayashi T, Ishii M, Kisara N, Sasaki K, Nakayama H, Igarashi T, Obara N, Ueno Y, Morosawa T, Shimosegawa T1(OH) vitamin D3 supplementation improves the sensitivity of the immune-response during Peg-IFN/RBV therapy in chronic hepatitis C patients-case controlled trial.PLoS One ( 2013) 8(5): e63672PMID : 23717463
• Kondo Y, Uno K, Machida K, Terajima MPPARs and Liver Disease.PPAR Res ( 2013) 2013 896412PMID : 23476632
• Kondo Y, Ninomiya M, Kakazu E, Kimura O, Shimosegawa THepatitis B surface antigen could contribute to the immunopathogenesis of hepatitis B virus infection.ISRN Gastroenterol ( 2013) 2013 935295PMID : 23401786

2012年(10件)

• Kakazu E, Kondo Y, Shimosegawa TThe Relationship between Renal Dysfunction and Abnormalities of the Immune System in Patients with Decompensated Cirrhosis.ISRN Gastroenterol ( 2012) 2012 123826PMID : 23326675
• Kimura O, Kondo Y, Shimosegawa TPPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma.PPAR Res ( 2012) 2012 574180PMID : 23316217
• Kondo Y, Ueno Y, Shimosegawa TDouble filtration plasmapheresis could induce a favorable immune response for chronic hepatitis C therapy.Ther Apher Dial ( 2012) 16(5): 478-9PMID : 23046374
• Inoue J, Ueno Y, Kawamura K, Yamamoto T, Mano Y, Miura M, Kobayashi T, Niitsuma H, Kondo Y, Kakazu E, Ninomiya M, Kimura O, Obara N, Kawagishi N, Kinouchi Y, Shimosegawa TAssociation between S21 substitution in the core protein of hepatitis B virus and fulminant hepatitis.J Clin Virol ( 2012) 55(2): 147-52PMID : 22795596
• Kondo Y, Ueno Y, Ninomiya M, Tamai K, Tanaka Y, Inoue J, Kakazu E, Kobayashi K, Kimura O, Miura M, Yamamoto T, Kobayashi T, Igarashi T, Shimosegawa TSequential immunological analysis of HBV/HCV co-infected patients during Peg-IFN/RBV therapy.J Gastroenterol ( 2012) 47(12): 1323-35PMID : 22588246
• Kondo Y, Ueno Y, Shimosegawa TBiological significance of HCV in various kinds of lymphoid cells.Int J Microbiol ( 2012) 2012 647581PMID : 22518147
• Kogure T, Costinean S, Yan I, Braconi C, Croce C, Patel THepatic miR-29ab1 expression modulates chronic hepatic injury.J Cell Mol Med ( 2012) 16(11): 2647-54PMID : 22469499
• Ninomiya M, Ueno Y, Funayama R, Nagashima T, Nishida Y, Kondo Y, Inoue J, Kakazu E, Kimura O, Nakayama K, Shimosegawa TUse of illumina deep sequencing technology to differentiate hepatitis C virus variants.J Clin Microbiol ( 2012) 50(3): 857-66PMID : 22205816
• Tamai K, Shiina M, Tanaka N, Nakano T, Yamamoto A, Kondo Y, Kakazu E, Inoue J, Fukushima K, Sano K, Ueno Y, Shimosegawa T, Sugamura KRegulation of hepatitis C virus secretion by the Hrs-dependent exosomal pathway.Virology ( 2012) 422(2): 377-85PMID : 22138215
• Ninomiya M, Ueno Y, Shimosegawa TPBC: Animal Models of Cholangiopathies and Possible Endogenous Viral Infections.Int J Hepatol ( 2012) 2012 649290PMID : 22007316

2011年(16件)

• Kondo Y, Ueno Y, Shimosegawa TToll-like receptors signaling contributes to immunopathogenesis of HBV infection.Gastroenterol Res Pract ( 2011) 2011 810939PMID : 22190911
• Braconi C, Henry JC, Kogure T, Schmittgen T, Patel TThe role of microRNAs in human liver cancers.Semin Oncol ( 2011) 38(6): 752-63PMID : 22082761
• Park JK, Kogure T, Nuovo GJ, Jiang J, He L, Kim JH, Phelps MA, Papenfuss TL, Croce CM, Patel T, Schmittgen TDmiR-221 silencing blocks hepatocellular carcinoma and promotes survival.Cancer Res ( 2011) 71(24): 7608-16PMID : 22009537
• Kondo Y, Ueno Y, Wakui Y, Ninomiya M, Kakazu E, Inoue J, Kobayashi K, Obara N, Shimosegawa TRapid reduction of hepatitis C virus-Core protein in the peripheral blood improve the immunological response in chronic hepatitis C patients.Hepatol Res ( 2011) 41(12): 1153-68PMID : 21951312
• Inoue J, Ueno Y, Wakui Y, Fukushima K, Kondo Y, Kakazu E, Ninomiya M, Niitsuma H, Shimosegawa TEnhanced replication of hepatitis B virus with frameshift in the precore region found in fulminant hepatitis patients.J Infect Dis ( 2011) 204(7): 1017-25PMID : 21881116
• Kakazu E, Ueno Y, Kondo Y, Inoue J, Ninomiya M, Kimura O, Wakui Y, Fukushima K, Tamai K, Shimosegawa TPlasma L-cystine/L-glutamate imbalance increases tumor necrosis factor-alpha from CD14+ circulating monocytes in patients with advanced cirrhosis.PLoS One ( 2011) 6(8): e23402PMID : 21858100
• Kondo Y, Ueno Y, Shimosegawa TDysfunction of Immune Systems and Host Genetic Factors in Hepatitis C Virus Infection with Persistent Normal ALT.Hepat Res Treat ( 2011) 2011 713216PMID : 21760997
• Kogure T, Lin WL, Yan IK, Braconi C, Patel TIntercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth.Hepatology ( 2011) 54(4): 1237-48PMID : 21721029
• Fukushima K, Ueno Y, Kawagishi N, Kondo Y, Inoue J, Kakazu E, Ninomiya M, Wakui Y, Saito N, Satomi S, Shimosegawa TThe nutritional index 'CONUT' is useful for predicting long-term prognosis of patients with end-stage liver diseases.Tohoku J Exp Med ( 2011) 224(3): 215-9PMID : 21701127
• Braconi C, Kogure T, Valeri N, Huang N, Nuovo G, Costinean S, Negrini M, Miotto E, Croce CM, Patel TmicroRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer.Oncogene ( 2011) 30(47): 4750-6PMID : 21625215
• Matsuura K, Tanaka Y, Kusakabe A, Hige S, Inoue J, Komatsu M, Kuramitsu T, Hirano K, Ohno T, Hasegawa I, Kobashi H, Hino K, Hiasa Y, Nomura H, Sugauchi F, Nojiri S, Joh T, Mizokami MRecommendation of lamivudine-to-entecavir switching treatment in chronic hepatitis B responders: Randomized controlled trial.Hepatol Res ( 2011) 41(6): 505-11PMID : 21585626
• Omar HA, Chou CC, Berman-Booty LD, Ma Y, Hung JH, Wang D, Kogure T, Patel T, Terracciano L, Muthusamy N, Byrd JC, Kulp SK, Chen CSAntitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma.Hepatology ( 2011) 53(6): 1943-58PMID : 21391227
• Inoue J, Ueno Y, Shimosegawa TManagement of chronic hepatitis B patients: efficacy & limitation of nucleos(t)ide analogues.Indian J Med Res ( 2011) 133 11-3PMID : 21321415
• Braconi C, Valeri N, Kogure T, Gasparini P, Huang N, Nuovo GJ, Terracciano L, Croce CM, Patel TExpression and functional role of a transcribed noncoding RNA with an ultraconserved element in hepatocellular carcinoma.Proc Natl Acad Sci U S A ( 2011) 108(2): 786-91PMID : 21187392
• Kondo Y, Ueno Y, Kakazu E, Kobayashi K, Shiina M, Tamai K, Machida K, Inoue J, Wakui Y, Fukushima K, Obara N, Kimura O, Shimosegawa TLymphotropic HCV strain can infect human primary naïve CD4+ cells and affect their proliferation and IFN-γ secretion activity.J Gastroenterol ( 2011) 46(2): 232-41PMID : 20714907
• Inoue J, Ueno Y, Wakui Y, Niitsuma H, Fukushima K, Yamagiwa Y, Shiina M, Kondo Y, Kakazu E, Tamai K, Obara N, Iwasaki T, Shimosegawa TFour-year study of lamivudine and adefovir combination therapy in lamivudine-resistant hepatitis B patients: influence of hepatitis B virus genotype and resistance mutation pattern.J Viral Hepat ( 2011) 18(3): 206-15PMID : 20367795

2010年(7件)

• Kimura O, Takahashi T, Ishii N, Inoue Y, Ueno Y, Kogure T, Fukushima K, Shiina M, Yamagiwa Y, Kondo Y, Inoue J, Kakazu E, Iwasaki T, Kawagishi N, Shimosegawa T, Sugamura KCharacterization of the epithelial cell adhesion molecule (EpCAM)+ cell population in hepatocellular carcinoma cell lines.Cancer Sci ( 2010) 101(10): 2145-55PMID : 20707805
• Tamai K, Tanaka N, Nakano T, Kakazu E, Kondo Y, Inoue J, Shiina M, Fukushima K, Hoshino T, Sano K, Ueno Y, Shimosegawa T, Sugamura KExosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein.Biochem Biophys Res Commun ( 2010) 399(3): 384-90PMID : 20673754
• Kondo Y, Ueno Y, Kobayashi K, Kakazu E, Shiina M, Inoue J, Tamai K, Wakui Y, Tanaka Y, Ninomiya M, Obara N, Fukushima K, Ishii M, Kobayashi T, Niitsuma H, Kon S, Shimosegawa THepatitis B virus replication could enhance regulatory T cell activity by producing soluble heat shock protein 60 from hepatocytes.J Infect Dis ( 2010) 202(2): 202-13PMID : 20533879
• Obara N, Fukushima K, Ueno Y, Wakui Y, Kimura O, Tamai K, Kakazu E, Inoue J, Kondo Y, Ogawa N, Sato K, Tsuduki T, Ishida K, Shimosegawa TPossible involvement and the mechanisms of excess trans-fatty acid consumption in severe NAFLD in mice.J Hepatol ( 2010) 53(2): 326-34PMID : 20462650
• Wakui Y, Inoue J, Ueno Y, Fukushima K, Kondo Y, Kakazu E, Obara N, Kimura O, Shimosegawa TInhibitory effect on hepatitis B virus in vitro by a peroxisome proliferator-activated receptor-gamma ligand, rosiglitazone.Biochem Biophys Res Commun ( 2010) 396(2): 508-14PMID : 20430009
• Fukushima K, Ueno Y, Shimosegawa TTreatment of Primary Biliary Cirrhosis: A new challenge?Hepatol Res ( 2010) 40(1): 61-8PMID : 20156299
• Kumada H, Okanoue T, Onji M, Moriwaki H, Izumi N, Tanaka E, Chayama K, Sakisaka S, Takehara T, Oketani M, Suzuki F, Toyota J, Nomura H, Yoshioka K, Seike M, Yotsuyanagi H, Ueno YGuidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan.Hepatol Res ( 2010) 40(1): 1-7PMID : 20156295

2009年(10件)

• Kondo Y, Ueno Y, Shimosegawa TImmunopathogenesis of hepatitis B persistent infection: implications for immunotherapeutic strategies.Clin J Gastroenterol ( 2009) 2(2): 71-9PMID : 26192169
• Kakazu E, Ueno Y, Kondo Y, Fukushima K, Shiina M, Inoue J, Tamai K, Ninomiya M, Shimosegawa TBranched chain amino acids enhance the maturation and function of myeloid dendritic cells ex vivo in patients with advanced cirrhosis.Hepatology ( 2009) 50(6): 1936-45PMID : 19885880
• Inoue JFactors involved in the development of fulminant hepatitis B: Are the mutations of hepatitis B virus implicated?Hepatol Res ( 2009) 39(11): 1053-5PMID : 19878349
• Inoue J, Ueno Y, Nagasaki F, Wakui Y, Kondo Y, Fukushima K, Niitsuma H, Shimosegawa TEnhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis.Virology ( 2009) 395(2): 202-9PMID : 19850315
• Kido O, Fukushima K, Ueno Y, Inoue J, Jefferson DM, Shimosegawa TCompensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of inflammatory cholangiopathy.Lab Invest ( 2009) 89(12): 1374-86PMID : 19823170
• Inoue J, Takahashi M, Mizuo H, Suzuki K, Aikawa T, Shimosegawa T, Okamoto HNucleotide substitutions of hepatitis E virus genomes associated with fulminant hepatitis and disease severity.Tohoku J Exp Med ( 2009) 218(4): 279-84PMID : 19638731
• Kogure T, Ueno Y, Sekiguchi S, Ishida K, Igarashi T, Wakui Y, Iwasaki T, Shimosegawa TLiver cell adenoma showing sequential alteration of radiological findings suggestive of well-differentiated hepatocellular carcinoma.World J Gastroenterol ( 2009) 15(10): 1267-72PMID : 19291830
• Inoue J, Ueno Y, Nagasaki F, Akahane T, Fukushima K, Kogure T, Kondo Y, Kakazu E, Tamai K, Kido O, Nakagome Y, Ninomiya M, Obara N, Wakui Y, Takahashi M, Okamoto H, Shimosegawa TSporadic acute hepatitis E occurred constantly during the last decade in northeast Japan.J Gastroenterol ( 2009) 44(4): 329-37PMID : 19271116
• Kogure T, Ueno Y, Kimura O, Kondo Y, Inoue J, Fukushima K, Iwasaki T, Shimosegawa TA novel third generation bisphosphonate, minodronate (YM529), prevented proliferation and migration of hepatocellular carcinoma cells through inhibition of mevalonate pathway.Hepatol Res ( 2009) 39(5): 479-89PMID : 19207585
• Kondo Y, Machida K, Liu HM, Ueno Y, Kobayashi K, Wakita T, Shimosegawa T, Lai MMHepatitis C virus infection of T cells inhibits proliferation and enhances fas-mediated apoptosis by down-regulating the expression of CD44 splicing variant 6.J Infect Dis ( 2009) 199(5): 726-36PMID : 19199548

2008年(10件)

• Kogure T, Ueno Y, Fukushima K, Nagasaki F, Kondo Y, Inoue J, Matsuda Y, Kakazu E, Yamamoto T, Onodera H, Miyazaki Y, Okamoto H, Akahane T, Kobayashi T, Mano Y, Iwasaki T, Ishii M, Shimosegawa TPegylated interferon plus ribavirin for genotype Ib chronic hepatitis C in Japan.World J Gastroenterol ( 2008) 14(47): 7225-4230PMID : 19084938
• Tamai K, Toyoshima M, Tanaka N, Yamamoto N, Owada Y, Kiyonari H, Murata K, Ueno Y, Ono M, Shimosegawa T, Yaegashi N, Watanabe M, Sugamura KLoss of hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration.Am J Pathol ( 2008) 173(6): 1806-17PMID : 19008375
• Obara N, Ueno Y, Fukushima K, Nakagome Y, Kakazu E, Kimura O, Wakui Y, Kido O, Ninomiya M, Kogure T, Inoue J, Kondo Y, Shiina M, Iwasaki T, Yamamoto T, Shimosegawa TTransient elastography for measurement of liver stiffness measurement can detect early significant hepatic fibrosis in Japanese patients with viral and nonviral liver diseases.J Gastroenterol ( 2008) 43(9): 720-8PMID : 18807134
• Matsuda Y, Yamagiwa Y, Fukushima K, Ueno Y, Shimosegawa TExpression of galectin-3 involved in prognosis of patients with hepatocellular carcinoma.Hepatol Res ( 2008) 38(11): 1098-111PMID : 18684128
• Fukushima K, Ueno Y, Inoue J, Wakui Y, Obara N, Kimura O, Kido O, Nakagome Y, Kakazu E, Matsuda Y, Kogure T, Kondo Y, Nagasaki F, Yamagiwa Y, Ashino Y, Shimosegawa TA case of HIV co-infected with hepatitis B virus precore/core deletion mutant treated by entecavir.Hepatol Res ( 2008) 38(8): 842-6PMID : 18498361
• Nagasaki F, Ueno Y, Niitsuma H, Inoue J, Kogure T, Fukushima K, Kobayashi K, Shimosegawa TAnalysis of the entire nucleotide sequence of hepatitis B causing consecutive cases of fatal fulminant hepatitis in Miyagi Prefecture Japan.J Med Virol ( 2008) 80(6): 967-73PMID : 18428142
• Machida K, Kondo Y, Huang JY, Chen YC, Cheng KT, Keck Z, Foung S, Dubuisson J, Sung VM, Lai MMHepatitis C virus (HCV)-induced immunoglobulin hypermutation reduces the affinity and neutralizing activities of antibodies against HCV envelope protein.J Virol ( 2008) 82(13): 6711-20PMID : 18417597
• Inoue J, Ueno Y, Kogure T, Nagasaki F, Kimura O, Obara N, Kido O, Nakagome Y, Kakazu E, Matsuda Y, Fukushima K, Segawa H, Nakajima I, Itoyama Y, Takahashi M, Okamoto H, Shimosegawa TAnalysis of the full-length genome of hepatitis B virus in the serum and cerebrospinal fluid of a patient with acute hepatitis B and transverse myelitis.J Clin Virol ( 2008) 41(4): 301-4PMID : 18291715
• Ninomiya M, Takahashi M, Nishizawa T, Shimosegawa T, Okamoto HDevelopment of PCR assays with nested primers specific for differential detection of three human anelloviruses and early acquisition of dual or triple infection during infancy.J Clin Microbiol ( 2008) 46(2): 507-14PMID : 18094127
• Fukushima K, Ueno Y, Kanegane H, Yamagiwa Y, Inoue J, Kido O, Nagasaki F, Kogure T, Kakazu E, Nakagome Y, Matsuda Y, Obara N, Kimura O, Shimosegawa TA case of severe recurrent hepatitis with common variable immunodeficiency.Hepatol Res ( 2008) 38(4): 415-20PMID : 18021227